Comparison of Tiaprofenic Acid and Etodolac on Pain and Edema Control After Third Molar Surgery

Yıl 2010, Cilt: 3 Sayı: 4, 498 - 504, 01.01.2010

Sevil Altundağ Kahraman Kahraman Güngör

Öz

Swelling and pain as a consequence of lower third molar surgery has been extensively studied and has become a model to evaluate the efficacy of many pharmacological therapeutic approaches. The ideal agent for use after third molar surgery should alleviate pain and reduce swelling, promote healing and have no unwanted effects. Fourteen patients with bilateral symmetrically impacted mandibular third molars participated in a crossover trial to evaluate the effectiveness of postoperative swelling and pain control using tiaprofenic acid and etodolac.Immediately before and after 2 days surgery, tiaprofenic acid were given 300mg orally on one side, 300mg of etodolac were given on the other side. Results were analyzed statistically by One-way ANOVA for the differences in follow-up periods at 5% level of significance

Anahtar Kelimeler

Third molar surgery, postoperative pain, edemas

Tiaprofenik Asit ve Etodolak’ın Gömülü Üçüncü Molar Diş Cerrahisi Sonrası Ağrı ve Ödem Kontrolündeki Etkinliklerinin Karşılaştırılması

Öz

Literatürde birçok farmakolojik terapötik çalışma, gömülü alt üçüncü molar diş cerrahisini takiben oluşan ödem ve ağrı modeli üzerine kurgulanmıştır. Gömülü üçüncü molar diş cerrahisi sonrası kullanılan ideal ajan ağrıyı ve ödemi azaltmalı, iyileşmeye yardımcı olmalı ve istenmeyen yan etkileri minimum olmalıdır. Sunulan bu çalışmada, bilateral simetrik gömülü üçüncü molar dişi bulunan ondört hastada, tiaprofenik asit ve etodolak etken maddeli iki ilacın, ağrı ve ödem üzerine olan etkisi karşılaştırılmıştır. Her iki operasyon 3 hafta arayla yapılmış olup, operasyondan hemen önce bir tarafta 300 mg. tiaprofenik asit, diğer tarafta 300mg etodolak oral olarak verilmiş ve hastaların postoperatif olarak bu ilaçlara en az 2 gün devam etmeleri sağlanmıştır. 28 dental operasyonu takiben iki gün boyunca ağrı ve ödem, Vizüel Anolog Skala VAS ve postero-anterior radyografi ile değerlendirilmiş ve sonuçlar istatistiksel olarak %5 anlamlılık düzeyinde karşılaştırılmıştır

Anahtar Kelimeler

Gömülü üçüncü molar, postoperatif ağrı, ödem

Kaynakça

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