Efficacy of Pit and Fissure Sealant Containing S-PRG Filler On Inhibition of Enamel Demineralization

Yıl 2024, Cilt: 13 Sayı: 3, 461 - 471, 24.09.2024

Yasemin Akın , Ayşegül Ölmez

https://doi.org/10.54617/adoklinikbilimler.1311482

Öz

The aim of this in-vitro study was evaluating the effectiveness of an S-PRG filler containing fissure sealant (Beautisealant) to inhibit enamel demineralization and to compare it with two different fluoride-containing (Helioseal-F) and non-fluoride-based (Helioseal) conventional fissure sealants, using enamel microhardness tester.
Material and Methods: In this study 30 caries-free 3rd molar teeth were used. Helioseal, Helioseal-F or Beautisealant fissure sealant was applied to the buccal surfaces of the teeth and subjected to a 14-day pH cycle. Lingual surfaces were the control group. Sections were taken in the bucco-lingual direction and cross-sectional microhardness values were measured at different depths. The significance of the mean difference between the groups was examined by One Way Analysis of Variance, the significance of the difference between buccal and lingual surfaces at different depths within the groups by Dependent t-test (p<0.05).
Results: It was determined that BeautiSealant fissure sealant gave statistically significantly higher values than other fissure sealants at some depths (p<0.001). When Helioseal, Helioseal-F and Beautisealant were evaluated individually, no significant difference was found between the depths in any material at different depths (p=0.784, p=0.568 and p=0.039, respectively).
Conclusions: S-PRG filler containing fissure sealant is found to be the most effective in preventing demineralization.

Anahtar Kelimeler

Inhibition of demineralization, Fissure sealant, Microharness, S-PRG filler

S-PRG Doldurucu İçeren Pit ve Fissür Örtücünün Minede Demineralizasyonu Engelleme Üzerine Etkisi

Öz

Amaç: Bu çalışmada fluorid içermeyen (Helioseal), fluorid içeren (Helioseal-F) ve S-PRG doldurucu içeren (BeautiSealant) rezin esaslı fissür örtücülerin demineralizasyonu engelleme özelliklerinin kesitsel mikrosertlik cihazı kullanılarak değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntem: Bu çalışmada çürüksüz 30 adet 3. Molar diş kullanılmıştır. Dişler bukkal yüzeylerine Helioseal, Helioseal-F veya Beautisealant fissür örtücü uygulanıp 14 gün pH siklusuna tabi tutulmuştur. Lingual yüzeyleri kontrol grubu olarak kullanılmıştır. Bukko-lingual yönde kesit alınıp, farklı derinliklerde kesitsel mikrosertlik değerleri ölçülmüştür. Gruplar arasında ortalamalar yönünden farkın önemliliği Tek Yönlü Varyans Analizi, gruplar içinde farklı derinliklerdeki bukkal ve lingual yüzeyler arasındaki farkın önemliliği Bağımlı t-testiyle incelenmiştir (p<0.05).
Bulgular: BeautiSealant fissür örtücünün bazı derinliklerde diğer fissür örtücülere göre istatistiksel olarak anlamlı düzeyde daha yüksek değerler verdiği tespit edilmiştir (p<0.001). Helioseal, Helioseal-F ve Beautisealant kendi içlerinde değerlendirildiklerinde farklı derinliklerde, hiçbir materyalde derinlikler arasında önemli bir fark bulunmamıştır (sırasıyla p=0.784, p=0.568 ve p=0.039).
Sonuç: Demineralizasyonu engellemede en etkin fissür örtücü materyalin S-PRG doldurucu içeren Beautisealant fissür örtücü olduğu gözlenmiştir.

Anahtar Kelimeler

Demineralizasyonu engelleme, Fissür örtücü, Mikrosertlik, S-PRG doldurucu

Kaynakça

• Wright JT, Crall JJ, Fontana M, Gillette EJ, Nový BB, Dhar V, et al. Evidence based clinical practice guideline for the use of pit-and-fissure sealants: a report of the American Dental Association and the American Academy of Pediatric Dentistry. J Am Dent Assoc 2016;147:672-82
• Papageorgiou SN, Dimitraki D, Kotsanos N, Bekes K, van Waws H. Performance of pit and fissure sealants according to tooth characteristics : a systematic review and meta- analysis. J Dent 2017;66:8–17
• Lam PP, Sardana D, Lo EC, Yiu CK. Fissure sealant in a nutshell. Evidence-based meta-evaluation of sealants’ effectiveness in caries prevention and arrest. J Evid Based Dent Pract 2021;21:1-33.
• Paglia L, Ferrazzano G, Beretta M. The Role of pit and fissure sealants in the prevention of dental caries. Bekes K, editor. Pit and fissure sealants. Switzerland: Springer; 2018. s. 35–50.
• de Souza Penha KJ, de Oliveira Roma FRV, dos Santos MJ, do Couto GAS, Firoozmand LM. In vitro and in vivo performance of self-conditioning sealants with pre-reacted glass for caries prevention. J Mech Behav Biomed Mater 2022;133:1-7.
• Ibrahim MS, Alabbas MS, Asomaly KU, AlMansour AA, Aljouie AA, Alzahrani MM, et al. Flexural strength, elastic modulus and remineralizing abilities of bioactive resin-based dental sealants. Polymers(Basel) 2021;14:1-13.
• Kashbour W, Gupta P, Worthington HV, Boyers D. Pits and fissure sealants versus fluoride varnishes for preventing dental decay in the permenant teethof children and adolescents. Cochrane Databese Syst Rev 2020;11:1-75.
• Kühnisch J, Mansmann U, Heinrich-Weltzien R, Hickel R. Longevity of materials for pit and fissure sealing--results from a meta-analysis. Dent Mater 2012;28:298-303.
• Dionysopoulos D, Sfeikos T, Tolidis K. Fluoride release and recharging ability of new dental sealants. Eur Arch Paediatr Dent 2016;17:45–51.
• Khalili Sadrabad Z, Safari E, Alavi M, Shadkar MM, Hosseini Naghavi SH. Effect of a fluoride-releasing fissure sealant and a conventional fissure sealant on inhibition of primary carious lesions with or without exposure to fluoride-containing toothpaste. J Dent Res Dent Clin Dent Prospect 2019;13:147–52.
• Zawaideh FI, Owais AI, Kawaja W. Ability of Pit and Fissure Sealant-containing Amorphous Calcium Phosphate to inhibit Enamel Demineralization. Int J Clin Pediatr Dent 2016;9:10-14.
• Alsaffar A, Tantbirojn D, Versluis A, Beiraghi S. Protective effect of pit and fissure sealants on demineralization of adjacent enamel. Pediatr Dent 2011;33:491-5.
• Salar DV, Garcia-Godoy F, Flaitz CM, Hicks MJ. Potential inhibition of demineralization in vitro by fluoride-releasing sealants. J Am Dent Assoc 2007;138: 502-6.
• Shimazu K, Ogata K, Karibe H. Evaluation of the ion-releasing and recharging abilities of a resin-based fissure sealant containing S-PRG filler. Dent Mater J 2011;30:923-7.
• Wang Y, Kaga M, Kajiwara D, Minamikawa H, Kakuda S, Hashimoto M, et al. Ion release and buffering capacity of S-PRG filler-containing pit and fissure sealant in lactic acid. Nano Biomedicine 2011;3:275-81.
• Kakuda S, Sidhu SK, Sano H. Buffering or non-buffering; an action of pit-and-fissure sealants. J Dent 2015;43:1285-9.
• Tantbirojn D, Douglas WH, Versluis A. Inhibitivive effect of resin-modified glass ionomer cement on remote enamel artificial caries. Caries Res 1997;31:275-80
• Hu W, Featherstone JD. Prevention of enamel demineralization: an in-vitro study using light-cured filled sealant. Am J Orthod Dentofacial Orthop 2005;128:592-600.
• Gomez J, Pretty IA, Santarpia RP, Cantore B, Rege A, Petrou I, et al. Quantitative light-induced fluorescence to measure enamel remineralization in vitro. Caries Res 2014;48:223-7.
• Shimazu K, Ogata K, Karibe H. Caries-preventive effect of fissure sealant containing surface reaction-type pre-reacted glass ionomer filler and bonded by self-etching primer. J Clin Pediatr Dent 2012;36:343-7.
• Kaga M, Kakuda S, Ida Y, Toshima H, Hashimoto M, Endo K, et al. Inhibition of enamel demineralization by buffering effect of S-PRG filler-containing dental sealant. Eur J Oral Sci 2014;122:78-83.
• Ibrahim MS, Balhaddad AA, Garcia IM, Collares FM,Weir MD, Xu HHK, et al. pH-responsive calcium and phosphate-ion releasing antibacterial sealants on carious enamel lesions in vitro. J Dent 2020;97:1-7.
• Yu OY, Zhao IS, Mei ML, Lo ECM, Chu CH. A review of the common models used in mechanistic studies on demineralization-remineralization for cariology research. Dent J(Basel) 2017;5:1-8.
• Ushimura K, Nakamura K, Matsuda Y, Minamikawa H, Abe S, Yawaka Y. Assessment of the inhibitory effects of fisure sealants on the demineralization of primary teeth using an automatic pH-cycling system. Dent Mater J 2016;35:316-24.
• Ogawa Y, Sayed M, Hiraishi N, Al-Haj Husain N, Tagami J, Özcan M, et al. Effect of surface pre-reacted glass ionomer containing dental sealant on the inhibition of enamel demineralization. J Func Biomater 2022;13:1-11
• Aoun A, Darwiche F, Al Hayek S, Doumit J. The fluoride debate: the pros and cons of fluoridation. Prev Nutr Food Sci 2018;23:171-180.
• Vatanatham K, Trairatvorakul C, Tantbirojn D. Effect of fluoride- and nonfluoride-containing resin sealants on mineral loss of incipient artificial carious lesion. J Clin Pediatr Dent 2006;30:320-4.
• Turkistani A, Bakhsh TA. Progression of enamel demineralisation around fissure sealants: optical coherence tomography study. Oral Health Prev Dent 2021;19:707-12.
• Penha KJS, Roma FRVO, Filho EMM, Ribeiro CCC, Firoozmand LM. Bioactive self-etching sealant on newly erupted molars: A split-mouth clinical trial. J Dent 2021;115:1-5