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Farklı Çok Modlu Adezivlerin Üç Aşındırma Modunda Sınıf V Kompozit Restorasyonların Mikrosızıntısına Etkisi

Yıl 2025, Cilt: 14 Sayı: 3, 177 - 188, 29.09.2025
https://doi.org/10.54617/adoklinikbilimler.1568236

Öz

Amaç: Bu in vitro çalışmanın amacı, farklı çok modlu adezivlerin üç asitleme modunda Sınıf V kompozit restorasyonların oklüzal ve gingival mikrosızıntısı üzerindeki etkilerini değerlendirmektir. Materyal ve Yöntem: Yüz yirmi insan moları rastgele dört gruba (G2-Bond Universal [GBU], Clearfil Tri-S Bond Universal [CTU], OptiBond Universal [OBU] ve Tokuyama Universal Bond [TUB]) ve ardından üç asitleme alt grubuna (total asitleme, kendinden asitli ve selektif asitleme) (n = 10) ayrıldı. Standart Sınf V kaviteler hazırlandı ve mikrohibrit bir kompozit rezin ile restore edildi. Tüm dişler, 5–55°C'de 30 saniye boyunca 10,000 kez termal siklusa maruz bırakıldı ve ardından 24 saat boyunca % 0,5 bazik fuksin çözeltisinde bekletildi. Dişler bukkolingual olarak kesildikten sonra, boya penetrasyonu ışık mikroskobu altında değerlendirildi. Ayrıca taramalı elektron mikroskobu analizi yapıldı. İstatistiksel değerlendirme için Kruskal-Wallis ve Mann-Whitney U testleri kullanıldı (p = 0,05). Sonuçlar: GBU, CTU, OBU ve TUB, sırasıyla kendinden asitli, selektif asitleme, total asitleme ve kendinden asitli modlarında en az mikrosızıntı skorunu göstermiştir. Kendinden asitli modunda, oklüzal kenarda GBU anlamlı derecede en az, CTU en çok mikrosızıntı gösterirken (p < 0,05), gingival kenarda adezivler arasında fark yoktu. Total asitleme modunda, GBU gingival kenarda en çok mikrosızıntı gösterirken (p < 0,05), oklüzal kenarda adezivler arasında anlamlı bir fark çıkmadı. Sonuç: Sınıf V kompozit restorasyonların oklüzal veya gingival mikrosızıntıları, adezivler ve asitleme modlarına bağlı olarak değişiklik göstermektedir.

Kaynakça

  • 1. Zotti F, Generali L, Campanella V, Saleh MHA, Salgarello S, Bertacci A, et al. Microleakage of direct restorations—Comparison between bulk-fill and traditional composite resins: Systematic review and meta-analysis. Eur J Dent 2021;15:755-67.
  • 2. Vieira S, Silva EJNL, Souza EM, De-Deus G, Belladonna FG, Lopes RT, et al. In vitro techniques for microleakage evaluation of coronary restorative materials: A scoping and mapping review. J Funct Biomater 2025;16:210.
  • 3. Atilan Yavuz S, Arslan S, Yazici AR, Yılmaz Atalı P, Tarçın B. Impact of acid and laser etching of enamel on microleakage in different adhesive systems. Lasers Med Sci 2024;39:181.
  • 4. Ren Z, Wang R, Zhu M. Comparative evaluation of bonding performance between universal and self-etch adhesives: In vitro study. Heliyon 2024;10:e30842.
  • 5. Alomran WK, Farooq I, Alrahlah A, Naseem M, Vohra F, Abduljabbar T. Evolution of dental resin adhesives—A comprehensive review. J Funct Biomater 2025;16:104.
  • 6. Van Meerbeek B, De Munck J, Yoshida Y, Inoue S, Vargas M, Vijay P, et al. Adhesion to enamel and dentin: current status and future challenges. Oper Dent 2003;28:215-35.
  • 7. Breschi L. Buonocore Memorial Lecture 2023: Changing operative mindsets with universal adhesives and cements. Oper Dent 2025;50:12-32.
  • 8. Tavares FVB, Machado AC, Soares LES, Soares CJ, Faria- E-Silva AL. Influence of adhesive systems containing different functional monomers on the longevity of bond strength at different dentin depths. Int J Adhes Adhes 2024;132:103723.
  • 9. Jäggi M, Lussi A, Büchel J, Eick S, Sculean A, Al-Ahmad A. Shear bond strength of universal adhesives to human enamel and dentin. J Esthet Restor Dent 2024;36:804-12.
  • 10. Demir İ. Süt ve daimi dişlerde kullanılan dentin adezivlerin universal özelliklerinin mikrosızıntı açısından değerlendirilmesi [thesis]. Ankara: Hacettepe University; 2013.
  • 11. Atalay C, Uslu A, Yazici AR. Does laser etching have an effect on application mode of a universal adhesive?—A microleakage and scanning electron microscopy evaluation. Microsc Res Tech 2021;84:125-32.
  • 12. Yalniz AM, Uzun İ, Arslan S, Öztürk C. Comparison of microleakage of Class V restoration with self-etch and selectiveetch adhesive systems: an in vitro study. Int J Prosthodont Restor Dent 2019;9:51-5.
  • 13. Furtado PRP, Oliveira LR, Rocha GM, Melo RM, Souza JCM, Zhang Y, et al. Synthesis and characterization of the dental adhesive monomer 10-MDP. Dent Mater 2024;40:2000-7.
  • 14. Khabadze Z, Ugurlu M, Korkmaz YN, Avcu E, Aydemir S. MDP-10 as the most important functional monomer of the last generation self-etching adhesive systems. J Int Dent Med Res 2024;17:1-8.
  • 15. Da Rosa WLO, Piva E, da Silva AF. Bond strength of universal adhesives: A systematic review and meta-analysis. J Dent 2015;43:765-76.
  • 16. Abdelkhalek E, Hamama HH, Mahmoud SH. HEMA-free versus HEMA-containing adhesive systems: A systematic review. Syst Rev 2025;14:17.
  • 17. de Groot AC, Rustemeyer T. 2‐Hydroxyethyl methacrylate (HEMA): A clinical review of contact allergy and allergic contact dermatitis. Contact Dermatitis 2024;90:1-16.
  • 18. Tsujimoto A, Barkmeier WW, Takamizawa T, Latta MA, Miyazaki M. Bond durability of two-step HEMA-free universal adhesive. J Funct Biomater 2022;13:134.
  • 19. Ahmet H, Betül ÜM. Effect of different MMP inhibitors on the bond strength and durability of an etch-and-rinse and a self-etch adhesive. ADO Journal of Clinical Sciences 2024;13:453-460.
  • 20. Hidari T, Shimizu Y, Takahashi M, Ikeda M, Foxton RM, Tagami J. Role of the functional monomer 10-methacryloyloxydecyl dihydrogen phosphate in dentin bond durability of universal adhesives in etch-&-rinse mode. Dent Mater J 2020;39:616-23.
  • 21. Elkaffas AA, Hamama HH, Mahmoud SH. Do universal adhesives promote bonding to dentin? A systematic review and meta-analysis. Restor Dent Endod 2018;43:e29.
  • 22. Deniz ŞT, Oglakci B, Dalkılıç EE. Farklı üniversal adeziv sistemler ile hemen dentin kapama işleminin kendinden bağlanabilen yapıştırma simanının bağlanma dayanımı üzerine etkisi. Acta Odontol Turc 2022;39:64-8.
  • 23. do Nascimento Foly JCS, Silva EJNL, Belladonna FG, De- Deus G, Souza EM, Lopes RT. Bonding performance of universal adhesive systems to enamel–Effects of the acidic composition. Dent Mater 2025;41:272-82.
  • 24. Madrigal EL, Piva E, Correr AB, Schneider LF, Moraes RR. The effect of curing mode of dual-cure resin cements on bonding performance of universal adhesives to enamel, dentin and various restorative materials. Dent Mater J 2021;40:446-54.
  • 25. Özkanoğlu S, Akin G. Dentin bond strength and microleakage comparison of three different universal adhesives. Cumhuriyet Dent J 2021;24:10-20.
  • 26. Van Meerbeek B, Yoshihara K, Van Landuyt K, Yoshida Y, Peumans M. From Buonocore’s pioneering acid-etch technique toself-adhering restoratives. J Adhes Dent 2020;22:7-34.
  • 27. Araújo-Neto VG, Silva EJNL, Belladonna FG, De-Deus G, Souza EM, Lopes RT. Effect of multi-layer applications of selfetch universal bonding agents on the adhesion of resin composite to enamel. Odontology 2025;113:252-60.

The Effect of Different Multimode Adhesives On Microleakage of Class V Composite Restorations in Three Etching Modes

Yıl 2025, Cilt: 14 Sayı: 3, 177 - 188, 29.09.2025
https://doi.org/10.54617/adoklinikbilimler.1568236

Öz

Objective: The aim of this in vitro study was to evaluate the effects of different multimode adhesives in three etching modes on occlusal and gingival microleakage of Class V composite restorations. Materials & Methods: One hundred and twenty human molars were randomly assigned to four groups (G2-Bond Universal [GBU], Clearfil Tri-S Bond Universal [CTU], OptiBond Universal [OBU], and Tokuyama Universal Bond [TUB]), and then three etching subgroups (total etch, self etch, and selective etch) (n = 10). Standard Class V cavities were prepared and restored with a microhybrid resin composite. All teeth were exposed to a 30-second thermal cycle for 10000 times at 5–55°C and then kept in 0.5% basic fuchsine solution for 24 hours. After the teeth were buccolingually cut, dye penetration was evaluated under a light microscope. Scanning electron microscopy analysis were also performed. Kruskal–Wallis and Mann–Whitney U tests were used for statistical evaluation (p  0.05). Results: GBU, CTU, OBU, and TUB showed the least microleakage score with self etch, selective etch, total etch and self etch modes, respectively. In self etch mode, GBU had the least and CTU had the most microleakage on occlusal margin (p < 0.05), while there was no difference among adhesives on gingival margin. In total etch mode, GBU had the most microleakage on gingival margin (p < 0.05), while there was no difference on occlusal margin among adhesives. Conclusion: Occlusal or gingival microleakages of Class V composite restorations vary depending on the adhesives and etching modes.

Etik Beyan

This study was approved by the Ethics Committee of the Mugla Sitki Kocman University under protocol number 230038/68-07/10/2023. Patients who were indicated for tooth extraction for orthodontic or periodontal treatment at Mugla Sitki Kocman University were informed about the study. After written and signed consent forms were obtained from the volunteer participants, the extracted teeth were stored for use in the study.

Teşekkür

The authors would like to acknowledge Nevin Guler Dincer for statistical analysing.

Kaynakça

  • 1. Zotti F, Generali L, Campanella V, Saleh MHA, Salgarello S, Bertacci A, et al. Microleakage of direct restorations—Comparison between bulk-fill and traditional composite resins: Systematic review and meta-analysis. Eur J Dent 2021;15:755-67.
  • 2. Vieira S, Silva EJNL, Souza EM, De-Deus G, Belladonna FG, Lopes RT, et al. In vitro techniques for microleakage evaluation of coronary restorative materials: A scoping and mapping review. J Funct Biomater 2025;16:210.
  • 3. Atilan Yavuz S, Arslan S, Yazici AR, Yılmaz Atalı P, Tarçın B. Impact of acid and laser etching of enamel on microleakage in different adhesive systems. Lasers Med Sci 2024;39:181.
  • 4. Ren Z, Wang R, Zhu M. Comparative evaluation of bonding performance between universal and self-etch adhesives: In vitro study. Heliyon 2024;10:e30842.
  • 5. Alomran WK, Farooq I, Alrahlah A, Naseem M, Vohra F, Abduljabbar T. Evolution of dental resin adhesives—A comprehensive review. J Funct Biomater 2025;16:104.
  • 6. Van Meerbeek B, De Munck J, Yoshida Y, Inoue S, Vargas M, Vijay P, et al. Adhesion to enamel and dentin: current status and future challenges. Oper Dent 2003;28:215-35.
  • 7. Breschi L. Buonocore Memorial Lecture 2023: Changing operative mindsets with universal adhesives and cements. Oper Dent 2025;50:12-32.
  • 8. Tavares FVB, Machado AC, Soares LES, Soares CJ, Faria- E-Silva AL. Influence of adhesive systems containing different functional monomers on the longevity of bond strength at different dentin depths. Int J Adhes Adhes 2024;132:103723.
  • 9. Jäggi M, Lussi A, Büchel J, Eick S, Sculean A, Al-Ahmad A. Shear bond strength of universal adhesives to human enamel and dentin. J Esthet Restor Dent 2024;36:804-12.
  • 10. Demir İ. Süt ve daimi dişlerde kullanılan dentin adezivlerin universal özelliklerinin mikrosızıntı açısından değerlendirilmesi [thesis]. Ankara: Hacettepe University; 2013.
  • 11. Atalay C, Uslu A, Yazici AR. Does laser etching have an effect on application mode of a universal adhesive?—A microleakage and scanning electron microscopy evaluation. Microsc Res Tech 2021;84:125-32.
  • 12. Yalniz AM, Uzun İ, Arslan S, Öztürk C. Comparison of microleakage of Class V restoration with self-etch and selectiveetch adhesive systems: an in vitro study. Int J Prosthodont Restor Dent 2019;9:51-5.
  • 13. Furtado PRP, Oliveira LR, Rocha GM, Melo RM, Souza JCM, Zhang Y, et al. Synthesis and characterization of the dental adhesive monomer 10-MDP. Dent Mater 2024;40:2000-7.
  • 14. Khabadze Z, Ugurlu M, Korkmaz YN, Avcu E, Aydemir S. MDP-10 as the most important functional monomer of the last generation self-etching adhesive systems. J Int Dent Med Res 2024;17:1-8.
  • 15. Da Rosa WLO, Piva E, da Silva AF. Bond strength of universal adhesives: A systematic review and meta-analysis. J Dent 2015;43:765-76.
  • 16. Abdelkhalek E, Hamama HH, Mahmoud SH. HEMA-free versus HEMA-containing adhesive systems: A systematic review. Syst Rev 2025;14:17.
  • 17. de Groot AC, Rustemeyer T. 2‐Hydroxyethyl methacrylate (HEMA): A clinical review of contact allergy and allergic contact dermatitis. Contact Dermatitis 2024;90:1-16.
  • 18. Tsujimoto A, Barkmeier WW, Takamizawa T, Latta MA, Miyazaki M. Bond durability of two-step HEMA-free universal adhesive. J Funct Biomater 2022;13:134.
  • 19. Ahmet H, Betül ÜM. Effect of different MMP inhibitors on the bond strength and durability of an etch-and-rinse and a self-etch adhesive. ADO Journal of Clinical Sciences 2024;13:453-460.
  • 20. Hidari T, Shimizu Y, Takahashi M, Ikeda M, Foxton RM, Tagami J. Role of the functional monomer 10-methacryloyloxydecyl dihydrogen phosphate in dentin bond durability of universal adhesives in etch-&-rinse mode. Dent Mater J 2020;39:616-23.
  • 21. Elkaffas AA, Hamama HH, Mahmoud SH. Do universal adhesives promote bonding to dentin? A systematic review and meta-analysis. Restor Dent Endod 2018;43:e29.
  • 22. Deniz ŞT, Oglakci B, Dalkılıç EE. Farklı üniversal adeziv sistemler ile hemen dentin kapama işleminin kendinden bağlanabilen yapıştırma simanının bağlanma dayanımı üzerine etkisi. Acta Odontol Turc 2022;39:64-8.
  • 23. do Nascimento Foly JCS, Silva EJNL, Belladonna FG, De- Deus G, Souza EM, Lopes RT. Bonding performance of universal adhesive systems to enamel–Effects of the acidic composition. Dent Mater 2025;41:272-82.
  • 24. Madrigal EL, Piva E, Correr AB, Schneider LF, Moraes RR. The effect of curing mode of dual-cure resin cements on bonding performance of universal adhesives to enamel, dentin and various restorative materials. Dent Mater J 2021;40:446-54.
  • 25. Özkanoğlu S, Akin G. Dentin bond strength and microleakage comparison of three different universal adhesives. Cumhuriyet Dent J 2021;24:10-20.
  • 26. Van Meerbeek B, Yoshihara K, Van Landuyt K, Yoshida Y, Peumans M. From Buonocore’s pioneering acid-etch technique toself-adhering restoratives. J Adhes Dent 2020;22:7-34.
  • 27. Araújo-Neto VG, Silva EJNL, Belladonna FG, De-Deus G, Souza EM, Lopes RT. Effect of multi-layer applications of selfetch universal bonding agents on the adhesion of resin composite to enamel. Odontology 2025;113:252-60.
Toplam 27 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Restoratif Diş Tedavisi
Bölüm Research Article
Yazarlar

Fatma Yılmaz 0000-0003-1954-6444

Sevgi Kurşun Bu kişi benim 0009-0001-9106-7619

Zeliha Öztürk Bu kişi benim 0000-0001-8445-7697

Yayımlanma Tarihi 29 Eylül 2025
Gönderilme Tarihi 17 Ekim 2024
Kabul Tarihi 22 Temmuz 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 14 Sayı: 3

Kaynak Göster

Vancouver Yılmaz F, Kurşun S, Öztürk Z. The Effect of Different Multimode Adhesives On Microleakage of Class V Composite Restorations in Three Etching Modes. ADO Klinik Bilimler Dergisi. 2025;14(3):177-88.