Evaluation of morbidity and mortality in preterm newborns with anemia

Öz

AIM: Anemia may cause negative clinical results to preterm newborns. But there are no enough studies to evaluate this problem. In this study, we aimed to evaluate the clinical results of very low birth weight (VLBW: <1500 g) preterm newborns with anemia. MATERIAL AND METHODS: In our study, preterm infants with <1500 g in our unit were included and the data were recorded retrospectively. Preterms who had cord hemoglobin (Hb) of <13 g/dL were enrolled into anemia group and preterms who had Hb of ≥13 g/dL were enrolled into the control group. Patients with and without anemia were compared in terms of demographic and clinical characteristics. RESULTS: According to umbilical cord Hb level, 22 preterm infants were included in the anemia group and 162 preterm infants were included in the group without anemia. A total of 184 infants were included in the study. In our results, the incidence of anemia at birth in VLBW infants were 11.95% (22/184). The first erythrocyte transfusion time (12.91±5.22 days) in the anemia group was significantly shorter than the group without anemia (17.68±9.34 days) (p=0.032). Severe intracranial hemorrhage (13.63%) and necrotizing enterocolitis (18.18%) among anemia group were found to be significantly higher than without anemia group (4.32%, 2.46%, respectively) (p=0.045, p=0.033, respectively). CONCLUSION: It should not be forgotten that some morbidities will increase if preterm infants, who are especially at risk for anemia at birth.

Anahtar Kelimeler

• Anemia
• morbidity
• mortality
• premature

Destekleyen Kurum

None

Proje Numarası

Yok

Etik Beyan

For this study, ethical approval was obtained from the Clinical Research Ethics Committee of Zekai Tahir Burak Women’s Health Training and Research Hospital with a decision dated 19.03.2019 and numbered 33/2019.

Teşekkür

None

Anemi ile doğan prematüre bebeklerdeki mortalite ve morbiditelerin değerlendirilmesi

Öz

AMAÇ: Prematüre bebeklerde anemi ile doğmak ciddi klinik sorunlara yol açabilir. Ancak özellikle ülkemizde bu konu üzerine yapılmış yeterince çalışma mevcut değildir. Çalışmamızda doğum sonrası anemi tespit edilen çok düşük doğum ağırlıklı (ÇDDA; <1500 g) prematüre bebeklerde klinik sonuçların değerlendirilmesi amaçlanmıştır. GEREÇ VE YÖNTEM: Çalışmamızda ünitemizde <1500 g doğan prematüre bebekler dahil edildi ve veriler retrospektif olarak kayıt edildi. Umbilikal kordondan bakılan hemoglobin (Hb) düzeyi <13 g/dL olanlar anemi grubuna ve HB düzeyi ≥13 g/dL olanlar anemi olmayan gruba dahil edildi. Anemi olan ve olmayan hastalar demografik ve klinik özellikleri açısından karşılaştırıldı. BULGULAR: Umbilikal kord Hb düzeyine göre 22 preterm bebek anemi, 162 preterm bebek anemi olmayan gruba dahil edilerek toplam 184 bebek çalışmaya alındı. Sonuçlarımızda ÇDDA bebeklerde doğumda anemi sıklığı %11,95 (22/184) olarak bulundu. Anemi olan grupta ilk eritrosit transfüzyon zamanı (12,91±5,22 gün) anemi olmayan gruba göre (17,68±9,34 gün) anlamlı olarak daha kısa bulundu (p=0,032). Anemi olan grupta ciddi İVK (%13,63) ile NEK oranları (%18,18) anemi olmayan gruba göre (sırasıyla, %4,32 ile %2,46) istatistiksel olarak anlamlı yüksek bulundu (sırasıyla, p=0,045, p=0,033) SONUÇ: Doğumda anemi açısından özellikle riskli olan preterm bebeklerin doğumda anemik olması durumunda bazı morbiditelerin artacağı unutulmamalıdır.

Anahtar Kelimeler

• Anemi
• morbidite
• mortalite
• prematüre

Destekleyen Kurum

Yok

Proje Numarası

Yok

Etik Beyan

Bu çalışma için Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi Klinik Araştırmalar Etik Kurulu'ndan 19.03.2019 tarih ve 33/2019 sayılı kararla etik onay alındı.

Teşekkür

Yok

Kaynakça

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