AMALGAM RESTORASYONLARININ TÜKÜRÜK CİVA KONSANTRASYONU VE TOTAL ANTİOKSİDAN SEVİYESİ ÜZERİNE ETKİSİNİN İNCELENMESİ

Öz

Bu çalışmanın amacı amalgam dolgusu bulunan ve bulunmayan bireyleri tükürük civa(Hg) seviyeleri ve total antioksidan aktiviteleri (TAA) arasındaki ilişkiyi incelemektir.

Çalışmaya 35 amalgam dolgulu , 13 amalgam dolgusu toplam 48 birey katıldı.Amalgam dolgulu bireylerin ağızlarından ölçü alındı ve restorasyonların yüzey alanları hesaplandı.Tüm bireylerde uyarılmamış tükürük örnekleri toplanarak , tükürük Hg ve TAA düzeyleri belirlendi.

Ortalama tükürük Hg düzeyleri amalgam dolgulu bireylerde 21.41±26.07µg/l ,amalgam dolgusu bulunmayan bireylerde 5.88±2.57µg /l olarak tespit edildi.Tükürük Hg konsantrasyonlarınınamalgam dolgularının sayısıyla pozitif korelasyon gösterdiği  ve dental amalgam olmayan bireylerde istatistiksel olarak daha düşük olduğu belirlendi. (p<0.001)

Amalgam dolguların toplam yüzey alanları veokluzal yüzey alanları ortalamaları ise sırayla 193.83±85.74 mm² ve 153.90±64.87 mm²  olarak tespit edildi.İstatistiksel olarak restorasyonların toplam alanları ile tükürük Hg seviyesi arasında bir korelasyon bulunmamasına karşın ( p>0.05), restorasyonların yüzey alanları ile tükürük Hg seviyesi arasında  pozitif bir ilişki bulundu (p<0.05).

Ortalama TAA seviyeleri ise amalgam dolgulu bireylerde 0.61±0.39 mmol/l, amalgam dolgusuz grupta ise 0,49±0.13 mmol/l idi.

Gerek amalgam dolgu sayısının ve gerekse amalgam restorasyonlarının  toplam ve okluzal alanlarının tükürük TAA konsantrasyonları ile bir korelasyon göstrmediği saptandı( p>0.05).

Bu çalışmanın sonuçları amalgam dolguların tükürükteki Hg’nin başlıca kaynaklarından biri olduğunu ve bu restorasyonların okluzal yüzey alanlarının tükürük Hg düzeyi üzerinde etkili bir unsur olmasına karşın. Bu etkinin tükürüğün TAA durumu üzerinde önemli olmadığını gösterdi.

 

Anahtar Kelimeler

• tükürük,civa

THE EFFECTS OF AMALGAM RESTORATIONS ON SALIVARY MERCURY CONCENTRATIONS AND TOTAL ANTIOXIDANT ACTIVITY

Öz

The aim of the present study was to examine the relationship between mercury (Hg) levels and Total Antioksidant Activity (TAA) in saliva of subjects having amalgam restorations and having not such fillings.

A total of 48 subjects participated in this study , 35 whom hadamalgam restorations and the 13 had no dental amalgams. In the amalgam group silicon impressions were taken and the total surface and occlusal surface areas of filings were calculated. Unsitimulated saliva samples of all subjects were collected and the levels of Hg and TAA were determined.

The mean Hg concentrations of saliva determined as 21.41±26.07µg/l in subjects with amalgam restorations, and were 5.88±2.57µg /l in subjects without amalgams. Saliva Hg concentrations were found to be positively correlated with the number of amalgam fillings and were statistically lower in the group without dental amalgams . (p<0.001). the mean total and occlusal surface areas of the amalgam fillings were determined as 193.83±85.74 mm² and 153.90±64.87 mm2 , respectively. Statically although there were no correlation between the total surface area of the restorations and salivary Hg levels ( p>0.05),   a positive relationship were found between the occlusal surface area of the amalgam fillings and Hg levels of saliva (p<0.05).

The mean TAA levels were 0.61±0.39 mmol/l for amalgam group and 0,49±0.13 mmol/l for the non amalgam group . It was found that neither the number of amalgam fillings nor the total surface and occlusal surface area of the restorations did not correlated with the salivary TAA concentrations ( p>0.05).

The results of the study showed that although amalgam fillings were one the sources of Hg in saliva and the occlusal surface area of these restorations were an effective factor on the salivary Hg levels, These influences were not important on the TAA statusof the saliva.

Anahtar Kelimeler

• saliva,mercury

Kaynakça

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