NEUROMYELITIS OPTICA DEVELOPİNG AFTER RECURRENT TRANSVERS MYELİTİS

Öz

Neuromyelitis optica NMO or Devic’s disease, is an idiopathic immune-mediated inflammatory demyelinating disease of the central nervous system mainly affecting the optic nerve and spinal cord. The main clinical characteristics of NMO are optic neuritis and transverse myelitis TM . NMO-TM is usually severe and typically longitudinally extensive TM LETM ; extending over 3 or more vertebral segments. LETM is usually associated with neuromyelitis optica NMO , but systemic autoimmune diseases Sjögren’s syndrome SS , systemic lupus erythematosus SLE , antiphospholipid syndrome, neuroinflammatory conditions Behcet’s disease, sarcoidosis , multiple sclerosis MS , and infectious diseases should always be considered. The correct diagnosis of NMO is of paramount importance for giving appropriate therapy. NMO is different from other demyelinating diseases clinically, radiologically, pathologically and in terms of treatment approaches

Anahtar Kelimeler

• Neuromyelitis optica,transverse myelitis,optic neuritis

TEKRARLAYAN TRANSVERS MİYELİT SONRASINDA GELİŞEN NÖROMİYELİTİS OPTİKA

Öz

Nöromyelitis optika NMO veya Devic hastalığı, santral sinir sisteminde ağırlıklı olarak optik sinir ve spinal kord tutulumuna neden olan idiopatik, immün aracılı ve inflamatuar demyelinizan bir hastalıktır. NMO'nun ana klinik özellikleri optik nörit ve transvers myelittir. NMO transvers myeliti genellikle ağırdır ve 3 veya daha fazla vertebra segmenti boyunca uzanan longitüdinal olarak yaygın transvers miyelittir longitüdinal ekstensiv transvers miyelit= LETM . LETM genellikle NMO ile ilişkili olup, sistemik otoimmün hastalıklar Sjögren sendromu,sistemik lupus eritematozus, antifosfolipid sendromu , nöroinflamatuvar durumlar Behçet hastalığı, sarkoidozis , multipl skleroz ve enfeksiyöz hastalıklar da göz önünde bulundurulmalıdır

Anahtar Kelimeler

• Neuromyelitis Optica,transvers miyelit,optik nörit

Kaynakça

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