HELİCOBACTER PYLORİ ERADİKASYONU TAKİBİNDE NÖTROFİL/LENFOSİT ORANININ ÖNEMİ

Yıl 2019, Cilt: 52 Sayı: 1, 38 - 42, 14.03.2019

Murat Ferhat Ferhatoğlu , Kazım Şenol Abdulcabbar Kartal Taner Kıvılcım Ali İlker Filiz

Öz

GİRİŞ
ve AMAÇ: Üst sindirim sistemine ait birçok hastalığın
etyopatogenezinde rol oynayan helicobacter pylori insanlarda en sık görülen
kronik bakteriyel enfeksiyondur. Prevalansı sosyokültürel ve coğrafi bölgelere
göre değişkenlik gösteren bu patojen dünya nüfusunun %30-%50'sini
etkilemektedir. Yıllar içerisine artan antibiyotik kullanımı ve sanitasyon
koşullarındaki değişiklikler nedeniyle bu yaygın enfeksiyonun davranış şekli de
değişiklik göstermiştir. Bu çalışmamızda birçok merkezde kolaylıkla yapılabilen
bir tetkik olan tam kan sayımında bulunan ve enfeksiyon belirteci olabilecek
parametreler ile helicobacter pylori enfeksiyonu arasındaki ilişkiyi inceledik.

YÖNTEM
ve GEREÇLER: Bu çalışmamızda Ocak
2016- Aralık 2016 üst gastrointestinal sistem endoskopisi yapılan 2939
hastanın tam kan sayımı ve patoloji verileri retrospektif olarak inceledik.

BULGULAR: Helicobacter
pylori varlığına göre nötrofil/lenfosit oranı arasında istatistiksel olarak anlamlı
farklılık saptanmış ve helicobacter pylori (+) olguların NLR değerleri helicobacter
pylori (-) olgulara göre yüksek bulunmuştur.

TARTIŞMA ve SONUÇ: Nötrofil/lenfosit
oranının helicobacter pylori eradikasyonu tedavi sürecini takip etmek için
yararlı olabileceğini düşünmekteyiz.

Anahtar Kelimeler

Helicobacter pylori, nötrofil/lenfosit, gastrit, eradikasyon

Kaynakça

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