KOMORBİD HASTALIKLARIN VE VİTAMİN DÜZEYLERİNİN UYKU KALİTESİNE ETKİSİNİN İNCELENMESİ

Yıl 2021, Cilt: 54 Sayı: 3, 366 - 371, 01.01.2022

Murat Yılmaz İrem Deniz Karakaya Sule Aydın Türkoğlu Serpil Kuyucu

https://doi.org/10.20492/aeahtd.878635

Öz

AMAÇ: Bu çalışmanın amacı, bir uyku kliniğinde polisomnografi (PSG) yapılan hastaların komorbid hastalıkları, vitamin düzeyleri ve uyku kalitesi arasındaki ilişkiyi araştırmaktır.
GEREÇ VE YÖNTEMLER: Bolu Abant İzzet Baysal Eğitim ve Araştırma Hastanesi Uyku Kliniği'nde Ocak 2018-Aralık 2018 tarihleri arasında PSG uygulanan 54 hasta çalışmaya dahil edildi. PSG ölçümleri uygun hazırlık prosedürlerini takiben uyku kliniğinde yapıldı.
BULGULAR: Çalışma grubunun 41'i (%78,8) erkek, 11'i (%21,2) kadındı. Ortalama yaş 49.25 ± 12.77 idi. Uyku apnesi sayısı (p = 0.013), santral apne (p = 0.037), apne / hipopne indeksi (p = 0.026) ve RDI (p = 0.021) diabetes melllitus (DM) hastalarında daha yüksekti. Hipertansiyonlu (HT) hastalarda (p = 0.021) ve koroner arter hastalığı (KAH) olanlarda (p = 0.013) REM uyku süresinin kısaldığı tespit edildi. D vitamini düzeyleri ile 2. evre uyku süresi arasında pozitif yönde zayıf korelasyon vardı (p = 0.032, r = 0.309). Folat seviyeleri (p = 0.039, r = -0.305) ve B12 vitamini seviyeleri (p = 0.035, r = -0.305) arttıkça arousal indeks değerleri azaldı.
SONUÇ: HT ve KAH uyku üzerinde çok sınırlı etkiye sahiptir. Ek olarak, bu çalışmada uyku parametrelerini en fazla DM olumsuz olarak etkilemiştir. Değerlendirilen vitamin düzeylerinin de uykuyu bazı parametrelerde çok sınırlı düzeyde etkilediği bulunmuştur.

Anahtar Kelimeler

komorbidite, polisomnografi, vitamin düzeyleri

EXAMINATION OF THE EFFECT OF COMORBID DISEASES AND VITAMIN LEVELS ON SLEEP QUALITY

Öz

AIM: The aim of this study was to investigate the relationship between comorbid diseases, vitamins levels and sleep quality of patients undergoing polysomnography (PSG) in a sleep clinic.
MATERIAL AND METHODS: Fifty-four patients who underwent PSG between January 2018 and December 2018 at Bolu Abant İzzet Baysal Training and Research Hospital Sleep Clinic were included in the study. PSG measurements were performed in the sleep clinic following appropriate preparatory procedures.
RESULTS: Of the study group, 41 (78.8%) were male and 11 (21.2%) were female. The mean age was 49.25 ± 12.77 years. The number of sleep apneas (p=0.013), central apnea (p=0.037), apnea / hypopnea index (p=0.026) and RDI (p=0.021) were higher in patients with diabetes melllitus (DM). It was found that REM sleep time was shortened in patients with hypertension (HT) (p=0.021) and patients with CAD (p=0.013). There was a positive weak correlation between vitamin D levels and stage 2 sleep duration (p=0.032, r = 0.309). As folate levels (p=0.039, r =-0.305) and vitamin B12 levels (p=0.035, r=-0.305) increased, arousal index values decreased.
CONCLUSION: HT and CAD have very limited effects on sleep. In addition, DM most negatively affected sleep parameters in this study. It was also found that the evaluated vitamin levels affect sleep only very limited in some parameters.

Anahtar Kelimeler

comorbidity, polysomnography, vitamin levels

Kaynakça

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