Hipotalamik hamartoma bağlı santral puberte prekoks ve faktör 7 eksikliği birlikteliği

Yıl 2021, Cilt: 54 Sayı: 3, 501 - 504, 01.01.2022

Muhammed Burak Selver Beray Selver Eklioğlu Mehmet Atabek Hüseyin Tokgöz Ümran Çalışkan

https://doi.org/10.20492/aeahtd.893090

Öz

Hipotalamik hamartom konjenital neoplastik olmayan tümör benzeri bir lezyondur. Santral puberte prekoksun santral sinir sistemi ile ilgili yaygın görülen organik sebeplerindendir. Bu olgu hipotalamik hamartoma bağlı küçük yaşta santral puberte prekoks görülmesi ve beraberinde faktör yedi eksikliğinin eşlik etmesi nedeniyle sunulmuştur.

Anahtar Kelimeler

puberte prekoks, hipotalamik hamartom, faktör yedi eksikliği

Kaynakça

• 1-Soriano-Guillén L, Argente J. Central precocious puberty, functional and tumor-related. Best Pract Res Clin Endocrinol Metab. 2019 Jun;33(3):101262.
• 2-Aguirre RS, Eugster EA. Central precocious puberty: From genetics to treatment. Best Pract Res Clin Endocrinol Metab. 2018 Aug;32(4):343-354.
• 3- Qasim BA, Mohammed AA. Hamartoma of hypothalamus presented as precocious puberty and epilepsy in a 10-year-old girl. Int J Surg Case Rep. 2020;77:170-173. doi: 10.1016/j.ijscr.2020.10.065
• 4- Yoon DY, Kim JH. An 11-month-old girl with central precocious puberty caused by hypothalamic hamartoma. Ann Pediatr Endocrinol Metab. 2016 Dec;21(4):235-239
• 5- Judge DM, Kulin HE, Page R, Santen R, Trapukdi S. Hypothalamic hamartoma: a source of luteinizing-hormone-releasing factor in precocious puberty. N Engl J Med. 1977 Jan 6;296(1):7-10.
• 6- Striano S, Striano P, Sarappa C, Boccella P. The clinical spectrum and natural history of gelastic epilepsy-hypothalamic hamartoma syndrome. Seizure. 2005 Jun;14(4):232-9.
• 7- Nguyen D, Singh S, Zaatreh M, Novotny E, Levy S, Testa F, Spencer SS. Hypothalamic hamartomas: seven cases and review of the literature. Epilepsy Behav. 2003 Jun;4(3):246-58.
• 8- Unger F, Schröttner O, Haselsberger K, Körner E, Ploier R, Pendl G. Gamma knife radiosurgery for hypothalamic hamartomas in patients with medically intractable epilepsy and precocious puberty. Report of two cases. J Neurosurg. 2000 Apr;92(4):726-31.
• 9- Alves C, Barbosa V, Machado M. Giant hypothalamic hamartoma: case report and literature review. Childs Nerv Syst. 2013 Mar;29(3):513-6.
• 10- Kotwal N, Yanamandra U, Menon AS, Nair V. Central precocious puberty due to hypothalamic hamartoma in a six-month-old infant girl. Indian J Endocrinol Metab. 2012 Jul;16(4):627-30.
• 11- Roberts JC. Evaluation of Abnormal Bleeding in Children. Pediatr Ann. 2020 Jan 1;49(1):e36-e42.
• 12- Rodriguez V, Warad D. Pediatric Coagulation Disorders. Pediatr Rev. 2016 Jul;37(7):279-91.