The Effect of Intermittent Fasting Diet and Light-Intensity Physical Activity on Serum Irisin Levels in Elderly Individuals

Yıl 2024, , 77 - 84, 29.04.2024

Hüsniye Bilge Sertdemir , Safiye Beyza Dursun , Shaafah Namulodı , Mehmet Salih Kaya , Farhri Bayıroğlu

https://doi.org/10.46332/aemj.1331280

Öz

Purpose: The aim of this study was to evaluate the effects of exercise and intermittent fasting diet on some anthropometric measurements and circulating irisin concentration and to investigate the relationship between irisin and body fat percentage in elderly subjects.

Materials and Methods: Forty-four elderly volunteers (21 men and 23 women) with a mean age of 69±9 years were randomly divided into 4 groups; Control (n=8), Bocce group (n=12), Intermittent fasting group (n=12), Bocce and Intermittent fasting group (n=12). Those in the control group continued with their normal activities. The Bocce group played Bocce for two hours five days a week. Those in the intermittent fasting group followed a 16-hour food restriction schedule on two non-consecutive days of the week. In addition to the Bocce Game, participants in the Intermittent Fasting and Bocce groups were given a food restriction regimen. The interventions were sustained for 12 weeks.

Results: There was no significant difference in serum irisin levels between the same groups before and after treatment (p>0.05). Body fat percentage decreased significantly in all groups except the increase in the control group (p<0.05). Body weight decreased significantly in Bo and IF groups (p<0.05). Although there was a significant decrease (p<0.05) in body fat percentage in the IF group compared to the control group, the similar significant difference observed in irisin levels was probably not the result of the experimental treatment, but was probably due to the inevitable heterogeneous distribution in terms of age between the groups. There was no correlation between body fat percentage and body weight change and circulating irisin levels (r=0.116, p=0.437; r=-0.145, p=0.649, respectively).

Conclusion: Intermittent fasting and Bocce intervention resulted in a decrease in body fat percentage and weight in elderly subjects, but not in serum irisin levels. This may be due to the slower response time to irisin in elderly individuals and/or the duration and intensity of exercise.

Anahtar Kelimeler

aged, bocce game, irisin, intermittent fasting

Aralıklı Açlık ve Hafif Yoğunluklu Fiziksel Aktivitenin Yaşlı Bireylerde Serum İrisin Düzeylerine Etkisi

Öz

Amaç: Bu çalışmanın amacı, yaşlı bireylerde egzersiz ve aralıklı açlık diyetinin bazı antropometrik ölçümler ve dolaşımdaki irisin konsantrasyonu üzerindeki etkilerini değerlendirmek ve irisin ile vücut yağ yüzdesi arasındaki ilişkiyi araştırmaktı.

Araçlar ve Yöntem: Yaş ortalaması 69±9 olan 44 yaşlı gönüllü (21 erkek ve 23 kadın) rastgele 4 gruba ayrıldı; Kontrol (n=8), Bocce grubu (n=12), Aralıklı açlık grubu (n=12), Bocce ve Aralıklı açlık grubu (n=12). Kontrol grubundakiler günlük rutinlerine devam etti. Bocce grubundakiler haftanın 5 günü 2 saat boyunca Bocce Oyunu oynadı. Aralıklı açlık grubundakilere ardışık olmayan haftanın iki günü 16 saatlik besin kısıtlaması programı uygulandı. Bocce ve Aralıklı açlık grubundakilere Bocce Oyununa ilaveten besin kısıtlaması programı uygulandı. Uygulamalara 12 hafta devam edildi.

Bulgular: Uygulama öncesi ve sonrası aynı gruplar karşılaştırıldığında serum irisin değerleri arasında anlamlı bir fark bulunmadı (p>0.05). Vücut yağ yüzdesi, kontrol grubundaki artış dışında diğer tüm gruplarda anlamlı olarak azaldı (p<0.05). Vücut ağırlığı Bo ve IF gruplarında önemli ölçüde azaldı (p<0.05). Uygulama sonrası gruplar kontrol grubu ile karşılaştırıldığında, IF grubunun vücut yağ yüzdesinde anlamlı azalma (p<0.05) görülmesine rağmen, irisin seviyelerinde gözlenen benzer anlamlı farklılık muhtemelen deneysel uygulamanın sonucu olmayıp, gruplar arasındaki yaş yönünden gelişen kaçınılmaz heterojen dağılımdan kaynaklanmaktaydı. Vücut yağ yüzdesi ve vücut ağırlığı değişimi ile dolaşımdaki irisin seviyeleri arasında korelasyon bulunmadı (sırasıyla r=0.116, p=0.437; r=-0.145, p=0.649).

Sonuç: Aralıklı açlık ve Bocce müdahalesi yaşlı bireylerde vücut yağ yüzdesi ve ağırlığında azalmaya sebep olurken, serum irisin değerlerinde anlamlı bir değişikliğe yol açmadı. Bu durum, yaşlı bireylerde irisine verilen cevap süresinin daha yavaş olmasından ve/veya egzersizin süre ve yoğunluğundan kaynaklanıyor olabilir.

Anahtar Kelimeler

aralıklı açlık, bocce oyunu, irisin, yaşlı

Kaynakça

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