Small cell carcinoma of the esophagus: A case report

Öz

Primary small cell carcinomas are rare tumors of the esophagus. The incidence rate of small cell carcinoma of the esophagus ranges between 0.8–2.4% of all esophageal malignancies. Small cell carcinoma of the esophagus carries a poor prognosis. In this case report, a 38-yearold female patient is presented whose endoscopic biopsy result was small cell carcinoma.

Anahtar Kelimeler

• Small cell carcinoma, esophagus, prognosis

Özofagusun küçük hücreli karsinomu: Olgu sunumu

Öz

Özofagusun primer küçük hücreli karsinomu özofagusun en nadir görülen tümörlerindendir. Tüm özofagus kanserleri içinde insidansı %0,8- 2,4 arasındadır. Prognozu diğer özofagus tümörlerine göre daha kötüdür. Bu yazıda endoskopik biyopsi sonucu küçük hücreli karsinom gelen 38 yaşında bayan hasta sunulmuştur.

Anahtar Kelimeler

• Küçük hücreli karsinom, özofagus, prognoz

Kaynakça

1. Peters JH, DeMeester TR. Esophagus and diaphragmatic hernia. In: Schwartz SI, Shires TG, Spencer FC Editors. Principles of Surgery. 7th ed.McGraw-Hill, 1999;1081-180.
2. Klumpp T, Macdonald JS. Esophageal cancer: epidemiology and pathology. In: Ahlgreen J, Macdonald J Editors. Gastrointestinal Oncology. Philadelphia. JB Lippincott Company 1992;71-80. 3. Sayek ‹ . Temel Cerrahi. 3. Bask›. Ankara. Günefl Kitabevi 2004; 1112-23.
3. Parkin DM, Pisani P, Ferlay J. Estimates of worldwide incidence of eighteen major cancers in 1985. Int J Cancer 1993;54:594-606.
4. Ökten ‹. Gastric transposition after esophageal resection. Türkiye Klinikleri J Surg Med Sci. 2007;3:82-92.
5. Daly JM, Fry WA, Little AG, et al. Esophageal cancer: results of an American College of Surgeons Patient Care Evaluation Study. J Am Coll Surg 2000;190:562-72.
6. Beyer KL, Marshall JB, Diaz-Arias AA, Loy TS. Primary small cell carcinoma of the esophagus. Report of 11 cases and review of the literature. J Clin Gastroenterol 1991;13:135-41.
7. Mc Fadden DW, Rudnicki M, Talamini MA. Primary small cell carcinoma of the esophagus. Ann Thorac Surg 1989;47:477-80.
8. Levenson RM, Ihde DC, Matthews MJ, et al. Small cell carcinoma presenting as an extrapulmonary neoplasm: sites of origin and response tochemotherapy. J Natl Cancer Inst 1981;67:607-12.

9. Orringer MB, Marshall B, Stirling MC. Transhiatal esophagectomy for bening and malignant disease. J Thoroc Cardiovasc Surg 1993; 105:265-76.
10. Geçim E. Çeviri editörü. Schwartz S. Principles of Surgery. 7. Bask›. Ankara. Ant›p Afi 2004;1101-99 .
11. Bremner RM, DeMeester TR. Surgical Treatment of esophagus carsinoma. Gastrointestinal Clin North Am 1991;20:743-63.
12. Genç V, Akyol C, Çakmak A, et al. A Rare Tumor: Primary Small Cell Carcinoma of Esophagus. Turkiye Klinikleri J Med Sci 2009;29: 1747-50.
13. Attar BM, Levendoglu H, Rhee H. Small cell carcinoma of the esophagus. Report of three cases and review of the literature. Dig Dis Sci 1990;35:145-52.
14. Ökten ‹. Özofagus kanserleri. Güncel Gastroenteroloji 1999;3:94104.
15. Uyan›ko¤lu A, Coflkun M, Binici DN. Do¤u Anadolu Bölgesinde üst gastrointestinal sistem kanser s›k›l›¤› ve da¤›l›m›. Turk J Gastroenterol 2010; 21 (Supp 1): 190, P304.
16. Cameron JL. Current Surgical Therapy. Sixth Edition, Ergüney S, Çiçek Y. Çeviri editörleri. 6. Bask›. ‹stanbul. Avrupa T›p Kitapç›l›k 2001;1-70.
17. Bolton JS, Sardia A, Bowen JC, Ellis JK. Transhiatal and transthoracic esophagectomy, a comparative study. J Surg Oncol 1992;51: 249-53.
18. Clark A, Fallowfield LJ. Quality of measurements in patients with malignant disease. A review. JR Soc Med 1986;79:130-66.
19. Dudhat SB, Shinde SR. Transhiatal esophagectomy for squamous cell carsinoma the esophagus. Dis Esophagus 1998;11:226-30.
20. Lee RB, Miller JI. Esophagectomy for cancer. Surg Clin North Am 1997;77:1169-96.
21. Pantvaidya GH, Pramesh CS, Deshpande MS, et al. Small cellcarcinoma of the esophagus: the Tata Memorial Hospital experience. Ann Thorac Surg 2002;74:1924-7.
22. Yau KK, Siu WT, Wong DC, et al. Non-operative management of small cell carcinoma of esophagus. Dis Esophagus 2007;20:48790.
23. Madroszyk A, Egreteau J, Martin L, et al. Small-cell carcinoma of the esophagus: report of three cases and review of the literature with emphasison therapy. Ann Oncol 2001;12:1321-5.