Does body mass index have any impact on 24-hour esophageal pH monitoring results?

Öz

Background and Aims: Gastroesophageal reflux disease and obesity are increasingly important health problems. The literature on the relationship between gastroesophageal reflux disease and obesity is conflicting. The most objective method of defining gastroesophageal reflux disease is 24-hour esophageal pH monitoring, which has a high specificity. We planned this retrospective study to investigate if there is a relationship between body mass index (BMI) and pH monitoring data in patients with gastroesophageal reflux disease. Materials and Methods: Data of 207 patients who underwent 24-hour esophageal pH monitoring were analyzed. The demographic characteristics and pH monitoring records were evaluated. The correlation between body mass index and 24-hour esophageal pH monitoring parameters was investigated. The World Health Organization categories of body mass index were used to group the patients. The esophageal 24-hour pH monitoring parameters were compared between body mass index groups. Results: Of the 207 patients, 93 were male (45%), 114 were female (55%) and the mean age was 42 ± 12 (range: 18-74 years). Patients with body mass index

Anahtar Kelimeler

• Body mass index, pH-monitoring, gastroesophageal reflux disease

Özofagusun 24 saatlik pH-metre izlemine hastanın vücut kitle indeksinin etkisi var mı?

Öz

Giriş ve Amaç: Gastroözefageal reflü hastalığı ve obezite önemli sağlık problemlerindendir. Obezite ve gastroözofageal reflü hastalığı arasındaki ilişki konusunda yapılan çalışma sonuçları çelişkilidir. Özofagusun 24 saatlik pH-izlemi gastroözofageal reflü hastalığı tanısında kullanılan yüksek spesifiteye sahip en objektif tanı yöntemidir. Bu çalışmamızı, gastroözofageal reflü hastalığı nedeniyle pH-metre yapılan hastalarımızda vücut kitle indeksi ile pH-metre verileri arasında bir ilişki olup olmadığını araştırmak için retrospektif olarak planladık. Gereç ve Yöntem: Özofagusun 24 saatlik pH-metre izleminin yapıldığı 207 hasta değerlendirildi. Hastaların demografik verileri ve pH-metre kayıtları incelendi. Vücut kitle indeksi ile 24 saatlik özofageal pH ölçüm parametreleri arasında korelasyon analizi yapıldı. Ardından hastalar Dünya Sağlık Örgütü’nün vücut kitle indeksi kategorilerine göre gruplara ayrıldı ve pH-izlem parametreleri açısından gruplar arasında fark olup olmadığı araştırıldı. Bulgular: Hastaların 93 tanesi erkek (%45), 114 tanesi kadındı (%55) ve yaş ortalamaları 42 ± 12 yıldı (18-74 yaş arasında). Vücut kitle indeksi < 25 olan hasta grubu ile ≥25 olan hasta grubu karşı- laştırıldığında özofageal pH ölçüm parametrelerinden reflü sayısı, uzun reflü sayısı, pH < 4 zaman yüzdesi ve total DeMeester skoru vücut kitle indeksi ≥25 olan grupta istatiksiksel olarak anlamlı derecede fazla bulundu. Sonuç: Asit reflü sayısı, uzun asit reflü sayısı, pH < 4 fraksiyone zaman ve total pH-metre skoru normal kilolu hasta grubunda fazla kilolu ve obez hastalardan anlamlı olarak düşük bulundu

Anahtar Kelimeler

• VKİ, pH-metre, GÖRH

Kaynakça

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