Kronik hepatitli ve karaciğer sirozlu hastaların biyoelektrik impedans yöntemi ile değerlendirilmesi

Öz

Giriş ve Amaç: Bu çalışmada, kronik hepatitli, sirozlu ve sağlıklı bireyler arasında biyoelektriksel impedans analiz yöntemi ile fark olup olmadığının araştırılması amaçlanmıştır. Gereç ve Yöntem: Çalışmaya Haziran 2012-2013 tarihleri arasında Harran Üniversitesi Tıp Fakültesi, Gastroenteroloji polikliniğinde takip edilen 31 kronik hepatit B ve kronik hepatit C hastası, 35 karaciğer sirozu ve 38 sağlıklı erişkin alındı. Olgular kronik hepatit, karaciğer sirozu ve sağlıklı kontrol olarak üç gruba ayrıldı. Olguların yaş, cinsiyet, boy, kilo, hematokrit, sodyum, potasyum değerleri ve biyoelektriksel impedans analiz ölçümü sonrası elde edilen değerler kaydedildi ve istatistiksel analiz yapıldı. Bulgular: Siroz grubunun hematokrit ve sodyum değeri anlamlı olarak düşüktü (p <0.05). Vücut kapasitans değeri kronik hepatitli grupta ve siroz grubunda kontrol grubuna göre yüksekti (p <0.05). Kronik hepatitli grupta rezistans kontrol grubuna göre düşüktü (p <0.05). Vücut hücre kitlesi kronik hepatitli grupta kontrol grubuna göre yüksekti (p <0.05). Kronik hepatitli grupta bazal metabolik hız kontrol grubuna göre yüksekti (p <0.05). Kronik hepatitli grubun yağsız vücut kitlesi kontrol grubuna göre yüksekti (p <0.05). Kronik hepatitli grubun intrasellüler sıvı ve total vücut suyu kontrol grubuna göre yüksekti (p <0.05). Faz açısı kronik hepatitli grupta diğer gruplara göre yüksek olsa da istatistiksel olarak anlamlı değildi (p >0.05). Sonuç: Biyoelektriksel impedans analiz ile sirotik grupta, kontrol ve kronik hepatitli grupla karşılaştırıldığında anlamlı bir değişiklik saptanmamasına rağmen kronik hepatitli grupta saptanan değişiklikler biyoelektriksel impedans analiz açısından ilerisi için ümit vericidir.

Anahtar Kelimeler

• Kronik hepatit,biyoelektrik impedans,karaciğer biyopsisi

Evaluation of chronic hepatitis and cirrhotic patients with bioelectrical impedance analysis

Öz

Background and Aims: The aim of this study was to investigate whether there was a difference between chronic hepatitis patients, cirrhotic patients, and healthy individuals with bioelectrical impedance analysis method. Materials and Methods: Between June 2012 and June 2013, 31 chronic hepatitis B and C patients, 35 cirrhotic patients who had been followed up in the Gastroenterology outpatient clinic at Harran University Faculty of Medicine and 38 healthy individuals were included in the study. Cases were divided into three groups as chronic hepatitis, liver cirrhosis, and healthy controls. Each patient’s age, sex, height, weight, hematocrit, sodium, potassium values, and values obtained after bioelectrical impedance analysis measurements were recorded and a statistical analysis was performed. Results: The cirrhotic group’s hematocrit and blood sodium level were significantly lower (p < .05). The body capacitance value in the chronic hepatitis and cirrhosis group was higher than that in the control group (p < .05). Resistance in the chronic hepatitis B group was lower than that in the control group (p < .05). The body cell mass value in the chronic hepatitis group was higher than that in the control group (p < .05). The chronic hepatitis group’s basal metabolic rate value was higher than that of the control group (p < .05). The chronic hepatitis group’s lean body mass value was higher than that of the control group (p < .05). The chronic hepatitis group’s intracellular water and total body water values were higher than both of these were in the control group (p < .05). The phase angle was higher in the chronic hepatitis group when compared with other groups, but was not statistically significant (p > .05). Conclusion: Although this study did not find significant changes between cirrhotic patients, chronic hepatitis patients, and control groups with bioelectrical impedance analysis, detecting any changes in patients with chronic hepatitis is promising for the future regarding bioelectrical impedance analysis.

Anahtar Kelimeler

• Chronic hepatitis,bioelectrical impedance,liver biopsy

Kaynakça

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