Kronik hepatitli ve karaciğer sirozlu hastaların biyoelektrik impedans yöntemi ile değerlendirilmesi

Yıl 2018, Cilt: 17 Sayı: 3, 137 - 141, 29.12.2018

Haşim Nar İdris Kırhan , Hüseyin Taşkıran Ahmet Uyanıkoğlu , Necati Yenice

https://doi.org/10.17941/agd.498555

Öz

Giriş ve Amaç: Bu çalışmada, kronik hepatitli,
sirozlu ve sağlıklı bireyler arasında biyoelektriksel impedans analiz yöntemi
ile fark olup olmadığının araştırılması amaçlanmıştır. Gereç ve Yöntem: Çalışmaya Haziran 2012-2013 tarihleri arasında Harran Üniversitesi Tıp Fakültesi, Gastroenteroloji
polikliniğinde takip edilen 31 kronik hepatit B ve kronik hepatit C hastası, 35
karaciğer sirozu ve 38 sağlıklı erişkin alındı. Olgular kronik hepatit,
karaciğer sirozu ve sağlıklı kontrol olarak üç gruba ayrıldı. Olguların yaş,
cinsiyet, boy, kilo, hematokrit, sodyum, potasyum değerleri ve biyoelektriksel
impedans analiz ölçümü sonrası elde edilen değerler kaydedildi ve istatistiksel
analiz yapıldı. Bulgular: Siroz grubunun hematokrit ve
sodyum değeri anlamlı olarak düşüktü (p <0.05). Vücut kapasitans değeri
kronik hepatitli grupta ve siroz grubunda kontrol grubuna göre yüksekti (p <0.05).
Kronik hepatitli grupta rezistans kontrol grubuna göre düşüktü (p <0.05).
Vücut hücre kitlesi kronik hepatitli grupta kontrol grubuna göre yüksekti (p <0.05).
Kronik hepatitli grupta bazal metabolik hız kontrol grubuna göre yüksekti (p <0.05).
Kronik hepatitli grubun yağsız vücut kitlesi kontrol grubuna göre yüksekti (p <0.05).
Kronik hepatitli grubun intrasellüler sıvı ve total vücut suyu kontrol grubuna göre
yüksekti (p <0.05). Faz açısı kronik hepatitli grupta diğer gruplara göre
yüksek olsa da istatistiksel olarak anlamlı değildi (p >0.05). Sonuç: Biyoelektriksel
impedans analiz ile sirotik grupta, kontrol ve kronik hepatitli grupla
karşılaştırıldığında anlamlı bir değişiklik saptanmamasına rağmen kronik
hepatitli grupta saptanan değişiklikler biyoelektriksel impedans analiz açısından
ilerisi için ümit vericidir.

Anahtar Kelimeler

Kronik hepatit, biyoelektrik impedans, karaciğer biyopsisi

Evaluation of chronic hepatitis and cirrhotic patients with bioelectrical impedance analysis

Öz

Background and Aims: The aim of this study
was to investigate whether there was a difference between chronic hepatitis
patients, cirrhotic patients, and healthy individuals with bioelectrical
impedance analysis method. Materials and
Methods: Between June 2012 and June 2013, 31 chronic hepatitis B and C
patients, 35 cirrhotic patients who had been followed up in the Gastroenterology
outpatient clinic at Harran University Faculty of Medicine and 38 healthy
individuals were included in the study. Cases were divided into three groups as
chronic hepatitis, liver cirrhosis, and healthy controls. Each patient’s age,
sex, height, weight, hematocrit, sodium, potassium values, and values obtained
after bioelectrical impedance analysis measurements were recorded and a statistical
analysis was performed. Results: The
cirrhotic group’s hematocrit and blood sodium level were significantly lower (p < .05). The body capacitance value
in the chronic hepatitis and cirrhosis group was higher than that in the
control group (p < .05).
Resistance in the chronic hepatitis B group was lower than that in the control
group (p < .05). The body cell
mass value in the chronic hepatitis group was higher than that in the control
group (p < .05). The chronic
hepatitis group’s basal metabolic rate value was higher than that of the
control group (p < .05). The chronic
hepatitis group’s lean body mass value was higher than that of the control
group (p < .05). The chronic
hepatitis group’s intracellular water and total body water values were higher
than both of these were in the control group (p < .05). The phase angle was higher in the chronic hepatitis
group when compared with other groups, but was not statistically significant (p > .05). Conclusion: Although this study did not find significant changes
between cirrhotic patients, chronic hepatitis patients, and control groups with
bioelectrical impedance analysis, detecting any changes in patients with
chronic hepatitis is promising for the future regarding bioelectrical impedance
analysis.

Anahtar Kelimeler

Chronic hepatitis, bioelectrical impedance, liver biopsy

Kaynakça

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