Dispeptik hastalarda Helicobacter pylori ile duodenumun dağınık beyaz noktasal lezyonları arasındaki ilişkinin değerlendirilmesi

Yıl 2022, Cilt: 21 Sayı: 2, 59 - 62, 25.08.2022

Sami Evirgen

https://doi.org/10.17941/agd.1154091

Öz

Giriş ve Amaç: Rutin endoskopik değerlendirmede genellikle karşılaştığımız ve intestinal lenfanjiektazi olarak değerlendirdiğimiz duodenumun dağınık beyaz noktasal lezyonlarının çoğunlukla belirgin bir nedeni veya klinik karşılığı bilinmemektedir. Çalışmamızda dağınık beyaz noktasal lezyonların sıklığını, patolojik karşılığını ve Helicobacter pylori ile olan ilişkisini değerlendirmeyi amaçladık. Gereç ve Yöntem: İç Hastalıkları ve Gastroenteroloji Bilim Dalımız polikliniklerine başvuran ve aynı endoskopist tarafından dispeptik yakınma şikayeti ile gastroskopileri uygulanan toplam 445 hastanın endoskopi bulguları retrospektif olarak değerlendirildi. Endoskopik bulgularında dağınık beyaz noktasal lezyonlar saptanan hastaların antrum ve duodenal biyopsileri alınarak histolojik olarak incelendi. Bulgular: Tüm hastaların %60’ı kadın (n = 245) ve yaşları ortalaması 47.1 yıl idi. İncelenen endoskopik raporlarda 39 (%8.8) hastada dağınık beyaz noktasal lezyonların olduğu saptandı. Dağınık beyaz noktasal lezyonlar saptanan hastaların biyopsilerinde 10 hastada (%26.3) intestinal lenfanjiektazi, 21 hastada (%55.2) kronik nonspesifik duodenit ve 7 hastada (%18.5) Giardia enfeksiyonu saptandı. Dağınık beyaz noktasal lezyonların saptandığı hastaların yarısında (n = 19) Helicobacter pylori pozitif olarak saptandı (p = 0.695). Helicobacter pylori sıklığı patolojik olarak intestinal lenfanjiektazi saptanmış grupta da istatiksel olarak farklı bulunmadı. Sonuç: Dispeptik yakınmalar ile gelen hastaların gastroskopilerinde dağınık beyaz noktasal lezyonların sıklığı %8.8 olarak bulundu. Bu hastaların ancak dörtte birinde patoloji ile konfirme intestinal lenfanjiektazi görülmektedir. Dağınık beyaz noktasal lezyonlar ve intestinal lenfanjiektazi saptanması ile Helicobacter pylori pozitifliği arasında bir ilişki saptanmamıştır.
Dispepsi, duodenal dağınık beyaz noktasal lezyonlar, Helicobacter pylori

Anahtar Kelimeler

Dispepsi, duodenal dağınık beyaz noktasal lezyonlar, Helicobacter pylori

Evaluation of the relationship between Helicobacter pylori and duodenal scattered white spots lesions in dyspeptic patients

Öz

Background and Aims: Duodenal scattered white spot lesions, which we usually encounter and evaluate as intestinal lymphangiectasia in routine endoscopic evaluation, are mostly unknown for a cause or clinical equivalent. In our study, we aimed to evaluate the frequency of duodenal scattered white spot lesions, their pathological findings and their relationship with Helicobacter pylori. Materials and Methods: A total of 445 patients admitted to Department of Internal Medicine and Gastroenterology and underwent gastroscopy by the same endoscopist who have dyspeptic complaints. The endoscopy findings of all patients were evaluated retrospectively. Antrum and duodenal biopsies were taken of patients with endoscopic findings of duodenal scattered white spot lesions and histologically examined. Results: Two-thirds of the patients were female (60%) and the mean age was 47.1 years. The examined endoscopic reports revealed that 39 (8.8%) patients had duodenal scattered white spot lesions. The biopsies of the patients with duodenal scattered white spot lesions revealed intestinal lymphangiectasia in 10 patients (26.3%), chronic nonspecific duodenitis in 21 patients (55.2%), and Giardia infection in 7 patients (18.5%). There were 19 (n = 19) patients with Helicobacter pylori was found to be positive (p = 0.695). The frequency of Helicobacter pylori was also not found to be statistically different in the pathologically intestinal lymphangiectasia group. Conclusion: The frequency of duodenal scattered white spot lesions in gastroscopies of patients with dyspeptic complaints was found to be 8.8%. However, the confirmation of intestinal lymphangiectasia with pathology is observed in only a quarter of these patients. The detection of duodenal scattered white spot lesions and intestinal lymphangiectasia, there is no correlation between Helicobacter pylori positivity.
Dyspepsia, duodenal scattered white spots lesions, Helicobacter pylori

Anahtar Kelimeler

Dyspepsia, duodenal scattered white spots lesions, Helicobacter pylori

Kaynakça

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