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Vitamin D, Vitamin B12, Folate, Iron and Creatine Kinase in Multiple Sclerotic Patients Who Smoke

Cilt: 2 Sayı: 1 30 Haziran 2021
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Vitamin D, Vitamin B12, Folate, Iron and Creatine Kinase in Multiple Sclerotic Patients Who Smoke

Abstract

It was aimed to investigate how vitamin D, B12, Folate, Iron and Creatine Kinase levels may change in patients with multiple sclerosis who smoke. For this purpose, the importance of vitamin D, B12, folate and iron in Multiple Sclerosis patients will be emphasized, and the contribution of the changes in the amount of these substances to the pathogenesis of the disease will be discussed. Multiple Sclerosis is a multi-factor autoimmune disease with a long and costly treatment process that seriously reduces the quality of life. Smoking, an important pathogen, is a preventable cause of death. Vitamin D is an important vitamin hormone that regulates calcium metabolism. Vitamin B12 and Folate are essential molecules for cognitive functions as well as nucleotide metabolism. Iron, which creates anemia in its deficiency and toxic effect by accumulating in excess, is one of the essential elements for human health. Creatine kinase is an enzyme found in many tissues that provides a practical way of energy reserve and utilization. As a result, we think that smoking may contribute negatively to the formation of Multiple Sclerosis and the disease process, with its effect of both initiating and increasing inflammation and reducing anti-inflammatory.

Keywords

Kaynakça

  1. [1] Kaminska J, Koper OM, Piechal K, Kemona H. Multiple sclerosis - etiology and diagnostic potential. Postepy Hig Med Dosw. 2017. 30;71(0):551-563.
  2. [2] Marabita F., Almgren M., Sjöholm L.K., Kular L., Liu Y., James T., Kiss N. B., Feinberg A.P., Olsson T., Kockum I., Alfredsson L., Ekström T.J., and Maja Jagodic. Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship. Sci Rep. 2017; 7: 14589.
  3. [3] Riccio P. and Rossano R. Diet, Gut Microbiota, and Vitamins D + A in Multiple Sclerosis. Neurotherapeutics. 2018;15(1):75-91.
  4. [4] Bardak N. Relationship Between Vitamin D and Multiple Sclerosis. Turkiye Klinikleri J Health Sci. 2018; 3(1): 66-70.
  5. [5] Wingerchuk D.M. Environmental Factors in Multiple Sclerosis: Epstein‐Barr Virus, Vitamin D, and Cigarette Smoking. Mount Sinai Journal of Medicine. 2011. 78;2: 221-230.
  6. [6] Pierrot-Deseilligny C, Souberbielle JC. Vitamin D and multiple sclerosis: An update. Mult Scler Relat Disord. 2017; 14:35-45.
  7. [7] Jiang CQ, Y H Chan, L Xu, Y L Jin, T Zhu, W S Zhang, K K Cheng, and T H Lam. Smoking and serum vitamin D in older Chinese people: cross-sectional analysis based on the Guangzhou Biobank Cohort Study. BMJ Open. 2016. 23;6(6).
  8. [8] Nele H., Korf H., Mathyssen C., Everaerts S., Smidt E.D., Dooms C., Yserbyt J., Gysemans C., Ramirez G.G., Mathieu C. and Janssens W. 1,25-Dihydroxyvitamin D Modulates Antibacterial and Inflammatory Response in Human Cigarette Smoke-Exposed Macrophages PLoS One. 2016; 11(8).

Ayrıntılar

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Naim Uzun *
Türkiye

Yayımlanma Tarihi

30 Haziran 2021

Gönderilme Tarihi

4 Haziran 2021

Kabul Tarihi

29 Haziran 2021

Yayımlandığı Sayı

Yıl 2021 Cilt: 2 Sayı: 1

Kaynak Göster

EndNote
Uzun N (01 Haziran 2021) Vitamin D, Vitamin B12, Folate, Iron and Creatine Kinase in Multiple Sclerotic Patients Who Smoke. Anatolian Journal of Biology 2 1 12–16.