Fleksible ve Rijid Sistoskopinin Hayat Kalitesi, Ağrı Skoru ve Alt Üriner Sistem Semptomları Üzerine Etkisi: Prospektif Randomize Bir Çalışma

Öz

Amaç: Fleksible ve rijid sistoskopinin; hayat kalitesi, ağrı skorlaması ve alt üriner sistem semptomları üzerine etkilerini karşılaştırmak. Gereç ve Yöntemler: Mesane tümörü öyküsü olan 168 hasta, prospektif olarak fleksible ve rijid sistoskopi kollarına randomize edildi. Yaşam kalitesi değerlendirmesi için, sistoskopi öncesinde ve bir hafta sonrasında kanser spesifik bir modül kullanıldı. Beklenen ve yaşanan ağrı, işlem öncesinde ve hemen sonrasında görsel bir analog skala ile kaydedildi. Alt üriner sistem semptomları, prosedürden önce ve prosedürden 2,7 ve 30 gün sonra Uluslararası Prostat Semptom Skoru ile değerlendirildi. Bulgular: Çalışmaya katılan 168 hastadan, 140’ı uygun bulunarak değerlendirildi. Sırasıyla, 69 ve 71 hasta fleksible ve rijid kollardandı. İşlem sonrası yaşanan ortalama ağrı skorları, fleksible kol için rijid kola kıyasla anlamlı derecede düşüktü sırasıyla, 2,57 ± 1,83 ve 4,48 ± 2,18, p

Anahtar Kelimeler

• Hayat kalitesi, Fleksible sistoskopi, Ağrı, Alt üriner sistem semptomları

The Effect of Flexible and Rigid Cystoscopy on Quality of Life, Pain Perception and Lower Urinary Tract Symptoms: A Prospective Randomized Study

Abstract

Objective: To compare the effects of flexible and rigid cystoscopy on quality of life, pain perception and lower urinary tract symptoms.Material and Methods: A total of 168 patients with bladder tumor history were prospectively randomized to flexible and rigid cystoscopy arms. For the quality of life assessment, a cancer specific module was administered just before and one week after cystoscopy. The expected and experienced pain was recorded by a visual analogue scale before and immediately after the procedure. Lower urinary tract symptoms were assessed using the International Prostate Symptom Score before and 2, 7 and 30 days after the procedure. Results: Of the 168 patients, 140 were eligible for the study and responded to the questionnaires. Of these, 69 and 71 patients were from the flexible and rigid arms, respectively. The mean visual analogue scale scores after the procedure were significantly lower for the flexible arm compared to the rigid arm 2.57±1.83 and 4.48±2.18, respectively, p

Keywords

• Quality of life, Flexible cystoscopy, Pain, Lower urinary tract symptoms

Kaynakça

1. Waters WB. Invasive bladder cancer - Where do we go from here? Editorial. J Urol 1996; 155: 1910-11.
2. Powell PH, Manohar V, Ramsden PD, Hall RR. A flexible cystoscope. Br J Urol 1984;56(6):622-4.
3. Seklehner S,Engelhardt P.F, Remzi M,Fajkovic H, Saratlija-Novakovic Z, Skopek M, Librenjak D. Anxiety and depression analyses of patients undergoing diagnostic cystoscopy. Quality of Life Research 2016; 25(9):2307-14.
4. Muezzinoglu T, Ceylan Y, Temeltas G, Lekili M, Buyuksu C. Evaluation of pain caused by urethrocystoscopy in patients with superficial bladder cancer: A perspective of quality of life. Onkologie 2005;28(5):260-4. Epub 2005 Apr 29.
5. Chen YT, Hsiao PJ, Wong WY, Wang CC, Yang SS, Hsieh CH. Randomized double-blind comparison of lidocaine gel and plain lubricating gel in relieving pain during flexible cystoscopy. J Endourol 2005;19(2):163-6.
6. McFarlane N, Denstedt J, Ganapathy S, Razvi H. Randomized trial of 10 ml and 20 ml of 2% intraurethral lidocaine gel and placebo in men undergoing flexible cystoscopy. J Endourol 2001;15(5):541-4.
7. Stav K, Leibovici D, Goren E, Livshitz A, Siegel YI, Lindner A, Zisman A. Adverse effects of cystoscopy and its impact on patients’ quality of life and sexual performance. Isr Med Assoc J 2004;6(8):474-8.
8. Krajewski W, Kościelska-Kasprzak K, Rymaszewska J, Zdrojowy R. How different cystoscopy methods influence patient sexual satisfaction, anxiety, and depression levels: a randomized prospective trial. Quality of Life Research, 2017; 26(3), 625-634.

9. Choong S,Whitfield HN, Meganathan V, Nathan MS, Razack A, Gleeson M. A prospective, randomized, double-blind study comparing lignocaine gel and plain lubricating gel in relieving pain during flexible cystoscopy. Br J Urol 1997;80(1):69-71.
10. Kobayashi T, Nishizawa K, Mitsumori K,Ogura K. Instillation of anesthetic gel is no longer necessary in the era of flexible cystoscopy: A crossover Study. J Endourol 2004;18(5):483-6.
11. Palit V, Ashurst HN, Biyani CS, Elmasray Y, Puri R, Shah T. Is using lignocaine gel prior to flexible cystoscopy justified? A randomized prospective study. Urol Int 2003;71(4):389-92.
12. Üçer O, Temeltaş G, Yüksel MB, Gümüş B, Müezzinoğlu T. Comparison of pain, quality of life, lower urinary tract symptoms and sexual function between flexible and rigid cystoscopy in follow-up male patients with non muscle invasive bladder cancer: A randomized controlled cross section single blind study. 32nd Annual EAU Congress, 24-28 March 2017, London, United Kingdom. European Urology Supplements 2017;16(3), e1159
13. Moseholm E, Rydahl-Hansen S, Overgaard D, Wengel HS, Frederiksen R, Brandt M, Lindhardt BØ. Health- related quality of life, anxiety and depression in the diagnostic phase of suspected cancer, and the influence of diagnosis. Health and Quality of Life Outcomes. 2016; 14(1): 80.
14. Ellis G, Pridgeon S, Lamb BW, Awsare NS, Osaghae S, Smith SG, Green JSA. Psychological distress in out-patients undergoing flexible cystoscopy for the investigation of bladder cancer. Journal of Clinical Urology 2015; 8(3):196-201.
15. Gilbert SM, Dunn RL, Hollenbeck BK, Montie JE, Lee CT, Wood DP, Wei JT. Development and validation of the Bladder Cancer Index: A comprehensive, disease specific measure of health related quality of life in patients with localized bladder cancer. Journal of Urology 2010; 183(5):1764-70.