Skar Tedavisinde Güncel Bir Yaklaşım: Nanofat Greft

Öz

Amaç: Vücuttaki skarlar, hastalar için estetik bir problem oluşturmanın yanısıra, özgüveni sarsarak sosyal hayatta iletişimi bozan ciddi durumlara da sebep olabilmektedir. Çalışmamızda yakın zamanda Tonnard tarafından tarif edilen 'nanofat greftin', yağ enjeksiyonu ile kombine kullanılmasının skar tedavisindeki etkisini araştırdık.Gereç ve Yöntemler: Çalışmamıza 20-42 yaş arasında yüzünde veya vücudunda skar nedeni ile Kasım 2016-Ocak 2018 arasında başvuran 7 hasta dahil edildi. 5 hastada skar yüzde, bir hastada göğüs ön yüz ve 1 hastada karında yerleşmişti. Bütün skar hastalarında deplase olan alanlara subkutan mikrofat enjeksiyonu uygulandı. Takiben bütün skar yüzeyini kaplayacak şekilde intradermal olarak nanofat enjeksiyonu yapıldı. Hastalar tedaviden 6 ay sonra deri kalitesinde artma ve skarda düzelme açısından doktor ve hasta tarafından değerlendirilmiştir.Bulgular: Tedaviden 6 ay sonra cilt kalitesinde artma, yüzey düzensizliği ve renk eşitsizliğinde azalma, genel görünümde düzelme açısından hasta ve doktor tarafından değerlendirildi. Bu çalışmaya göre tedavi sonunda hastaların ortalama tedavi yüzdeleri hasta değerlendirmesine göre %54,6- %78,5, doktor değerlendirmesine göre % 43,8- 67,8 arasındadır.Sonuç: Nanofat greft, zengin kök hücre içeriği, kolay hazırlanma ve kullanma kolaylığı avantajları göz önüne alındığında skar tedavisinde diğer yöntemlere ek olarak veya yalnız başına tercih edilebilecek bir yöntemdir. Ancak skar üzerine etkisini daha iyi analiz edebilmek için kontrollü randomize çalışmalara ihtiyaç duyulmaktadır

Anahtar Kelimeler

• Nanofat, Skar, Yağ enjeksiyonu, Yağ grefti

A Current Approach to Scar Treatment: Nanofat Graft

Abstract

Objective: Face and body scars can cause serious aesthetic and psychological problems that disturb the patients' self-confidence and their communication in social life. We investigated the effect of 'nanofat graft' which recently described by Tonnard, on scar treatment in combination with fat injection in this study.Material and Methods: Seven patients were included between the ages of 20-42 years who referred because of scar on their face or body between November 2016 and January 2018. The scar was located in the face in five patiens, in the front of the chest in one patient, and in the lower abdomen in one patient. Subcutaneous fat injections were performed to atrophic scar areas in all patients. Subsequently, nanofat injection was performed intradermally to cover the entire scar surface. Patients were evaluated by the patient and the physician for improvement of the sacrring and skin quality after 6 months of treatment.Results: Skin quality, surface irregularity, color inequality and overall appearance were evaluated by the patient and the physican. At the end of the treatment, the mean improvement percentages of the scars were 54.6% -78.5% according to the patient evaluation and 43.8-67.8% according to the physican evaluation.Conclusion: Nanofat graft which has certain advantages, such as rich stem cell content and ease of preparation and use, can be preferred alone or in combination with other methods of scar treatment. However, controlled randomized trials are needed to better analyze the effect of nanofat on the scar

Keywords

• Nanofat, Scar, Fat injection, Fat graft

Kaynakça

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