Sol Ana Koroner Hastalığı Prevalansının Kronik Böbrek Yetersizliği Olan ve Olmayan Hastalarda Karşılaştırılması: Eğilim Skor Eşleştirme Analizi

Öz

Amaç: Bu çalışmada kronik böbrek hastalığına KBH sahip hastalarda sol ana koroner LMCA hastalığının prevalansını ve bu prevalansın normal böbrek fonksiyonuna sahip hastalardan farklı olup olmadığını saptamayı amaçladık.Gereç ve Yöntemler: Koroner anjiyografi uygulanmış 502 ardışık stabil koroner arter hastası tarandı. 423 hasta son değerlendirmeye dahil edildi. LMCA hastalığının prevalansı KBH olan veya olmayan hasta gruplarında karşılaştırıldı. Eğilim skor analizi yöntemi ile 102 kronik böbrek yetersizliği hastası 102 normal böbrek fonksiyonuna sahip hasta ile eşleştirildi ve LMCA hastalığının sıklığı bu iki grupta karşılaştırıldı. Bulgular: Ortanca yaş 61,08±10,23 idi. KBH grubunda erkek cinsiyet ve diyabet anlamlı olarak daha fazla, sigara kullanımı ise anlamlı olarak daha azdı. Ortalama Gensini skoru KBH grubunda anlamlı olarak daha fazlaydı 58,66±33,77 vs. 57,62±28,69, p:0,002 . LMCA’da herhangi bir lezyon veya kritik lezyon varlığı iki grupta benzerdi. Birebir eğilim skor analizi yöntemi ile 102 KBH hastası 102 normal böbrek fonksiyonuna sahip hasta ile eşleştirildi. LMCA hastalığı sıklığı bu iki grupta yine benzer bulundu sırasıyla %21 vs %17,6, p:0,481 .Sonuç: KBH’ye sahip hastalarda kritik LMCA hastalık prevalansı normal böbrek fonksiyonuna sahip hastalardakinden farklı değildir. Bu benzerlik eğilim skor analizi sonrası da değişmemiştir

Anahtar Kelimeler

• Sol ana koroner hastalığı, Kronik böbrek hastalığı, Eğilim skor eşleştirme analizi

Comparison of Left Main Coronary Disease Prevalance in Patients with or without Chronic Kidney Disease: A Propensity Score Match Analysis

Abstract

Objective: In our study we sought to determine the prevalence of critical left main coronary artery LMCA disease in chronic kidney disease CKD and to compare it with the prevalence in patients with normal kidney function.Material and Methods: 502 consecutive patients with stable angina pectoris who underwent coronary angiography were screened. 423 patients were included in the final analysis. Prevalence of LMCA disease was compared between patients with or without CKD. 102 patients with CKD were matched with 102 patients without CKD using propensity score matching and the prevalence of LMCA disease was compared between these groups. Results: Mean age was 61.08±10.23. Male gender and diabetes were significantly higher whereas smoking was significantly lower in patients with CKD. Mean Gensini score was higher in patients with CKD 58.66±33.77 vs. 57.62±28.69, p:0.002 . Presence of any lesion or significant stenosis in LMCA did not differ between the groups. 102 patients with CKD matched with 102 patients with normal kidney function after 1:1 propensity score analysis. Prevalence of critical LMCA disease did not differ between matched CKD and non CKD groups 21% vs 17.6% respectively, p: 0.481 .Conclusion: In patients with CKD, the prevalence of a critical LMCA lesion was not different from the patients with normal kidney function. The similarity of the prevalence persisted after propensity score matching

Keywords

• Left main coronary disease, Chronic kidney disease, Propensity score match analysis

Kaynakça

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