Polikistik Over Sendromlu Hastalarda Tükürük Analizi ve DMFT İndeksleri

Öz

Amaç: Polikistik over sendromlu PKOS hastaların çeşitli parametreler dahilinde yapılan tükürük analizlerinin ve DMF-T indeks değerlerinin bu hastalıkla ilişkisini saptamaktır.Gereç ve Yöntemler: PKOS tanısı konulmuş 20 hastadan ve sağlıklı 20 bireyden tükürük örnekleri alındı. Tükürük pH’sı, tükürük akış hızı, kıvamı, tükürükteki Streptokokus Mutans St. Mutans varlığı aynı zamanda dişlerdeki DMF-T indeksleri değerlendirildi. Elde edilen sonuçların PKOS ile ilişkisi araştırıldı.Bulgular: PKOS’lu hasta grubunun DMF-T değerleri ve tükürük viskozitesi kontrol grubuna göre anlamlı olarak yüksekti p0.05 . PKOS grubunda DMF-T indeks değerleri ile St. Mutans, istirahat tükürük akış hızı ve pH’sı arasında anlamlı ilişki bulundu p

Anahtar Kelimeler

• Polikistik Over Sendromu, Tükürük, pH, St. Mutans

Saliva Analysis and DMFT Indexes in Patients with Polycystic Ovary Syndrome

Öz

Objective: To determine the relationship of various salivary analysis parameters and the DMF-T index in polycystic ovary syndrome PCOS .Material and Methods: Saliva samples were obtained from 20 patients with PCOS and 20 samples from healthy individuals. The pH, flow rate, viscosity of saliva and the level of Streptococcus mutans St. mutans were evaluated. The effects of PCOS on these features of saliva and the DMF-T index were observed and recorded.Results: The viscosity of saliva and DMF-T values were significantly higher for patients with PCOS compared to the control group p0.05 . In the PCOS group, a significant correlation was found between the DMF-T index values and the St. mutans and resting saliva flow rate/pH values p

Anahtar Kelimeler

• Polycystic ovary syndrome, Salivary, pH, St. Mutans

Kaynakça

1. Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 2004; 89:2745-9.
2. Group REASPCW. Revised 2003 consensus on diagnostic criteria and long‐term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 2004; 19:41-7.
3. Talbott EO, Guzick DS, Sutton-Tyrrell K, McHugh-Pemu KP, Zborowski JV, Remsberg KE, Kuller LH. Evidence for association between polycystic ovary syndrome and premature carotid atherosclerosis in middle-aged women. Arterioscler Thromb Vasc Biol 2000; 20:2414-21.
4. Kobaly K, Vellanki P, Sisk RK, Armstrong L, Lee JY, Lee J, Hayes MG, Urbanek M, Legro RS, Dunaif A. Parent- of-origin effects on glucose homeostasis in polycystic ovary syndrome. J Clin Endocrinol Metab 2014; 99:2961-6.
5. Salehi M, Bravo-Vera R, Sheikh A, Gouller A, Poretsky L. Pathogenesis of polycystic ovary syndrome: what is the role of obesity? Metabolism 2004; 53:358-76.
6. Dunaif A. Book CB. Clinical Research in Diabetes and Obesity. In: Draznin, Boris, Rizza, Robert eds. Contemporary Biomedicine. 2 th ed. Berlin: Springer, 1997:249-74.
7. Manfredi M, McCullough M, Vescovi P, Al‐Kaarawi Z, Porter S. Update on diabetes mellitus and related oral diseases. Oral Dis 2004; 10:187-200.
8. Hall GY, Hall JE. Tıbbi Fizyoloji, 13. Baskı. Ankara; Güneş Kitabevi, 1996.

9. Wong DT. Salivary Diagnostics: Amazing as it might seem, doctors can detect and monitor diseases using molecules found in a sample of spit. Am Sci 2008; 96:37-43.
10. Emekli N, Yarat A, Akbay Tunalı T, Öztürk Koç L, Alturfan EI. Tükürük Biyokimyası. İçinde: Tükürük Histolojisi, Fizyolojisi, Mikrobiyolojisi ve Biyokimyası. İstanbul: Nobel Tıp Kitabevleri, 2008.
11. Aktaş A, Giray B, Aktaş G. Tükürük (Salya); Özellikleri ve görevleri tanı açısından değeri. ADO J Clin Sci 2009; 3:361-7.
12. Whiley R, Beighton D. Current classification of the oral streptococci. Oral Microbiol Immunol 1998; 13:195-216.
13. Bowen W, Koo H. Biology of Streptococcus mutans-derived glucosyltransferases: role in extracellular matrix formation of cariogenic biofilms. Caries Res 2011; 45:69-86.
14. Bloemendal E, de Vet HC, Bouter LM. The value of bitewing radiographs in epidemiological caries research: a systematic review of the literature. J Dent 2004; 32:255- 64.
15. Mital P, Amit RD, Mital P, Hooja N, Priyanka. Dental caries and gingivitis in pregnant women. Sch J App Med Sci 2013; 1:718-23.
16. Legro RS, Gnatuk CL, Kunselman AR, Dunaif A. Changes in glucose tolerance over time in women with polycystic ovary syndrome: A controlled study. J Clin Endocrinol Metab 2005; 90:3236-42.
17. Mukherjee S, Maitra A. Molecular and genetic factors contributing to insulin resistance in polycystic ovary syndrome. Indian J Med Res 2010; 131:743-61.
18. Harwood K, Vuguin P, Di Martino-Nardi J. Current approaches to the diagnosis and treatment of polycystic ovarian syndrome in youth. Horm Res Paediatr 2007; 68: 209-17.
19. Tong H, Rudolf M, Muyombwe T, Duggal M, Balmer R. An investigation into the dental health of children with obesity: an analysis of dental erosion and caries status. Eur Arch Paediatr Dent 2014; 15:203-10.
20. Lamster IB, Lalla E, Borgnakke WS, Taylor GW. The relationship between oral health and diabetes mellitus. J Am Dent Assoc 2008; 139:19S-24S.
21. Tozoğlu Ü, Bilge OM. Tip 2 Diyabetli hastalarda Dmf İndeksi, Periodontal İndeks, tükürük akişi ve tükürük Ph’sinin değerlendirilmesi. Atatürk Üniv Diş Hek Fak Derg 2009:145-50.
22. Percy CA, Gibbs T, Potter L, Boardman S. Nurse-led peer support group: Experiences of women with polycystic ovary syndrome. J Adv Nurs 2009; 65:2046-55.
23. Garad R, Teede HJ, Moran L. An evidence-based guideline for Polycystic Ovary Syndrome. Aust Nurs J 2011; 19:30.
24. Gürbüz Ö, Altınbaş K, Kurt E. Psikiyatrik hastalarda ağız sağlığı. Psikiyatride Guncel Yaklasimlar 2011; 3:628-46.
25. Lindquist B, Emilson C. Distribution and prevalence of mutans streptococci in the human dentition. J Dent Res 1990; 69:1160-6.