Fetal Left Acheiria in Levetiracetam Use During Pregnancy: A Case Report

Öz

Abstract: Epilepsy is one of the common chronic disorders seen in women of reproductive age. There are serious maternal and fetal risks of having an epileptic seizure, so it is necessary to continue treatment during pregnancy. Congenital malformation (CM) rates increase especially with first-generation antiepileptic use. Levetiracetam (LEV) is a second generation antiepileptic with relatively few teratogenic side effects. Although there are publications about CM in pregnant women using LEV, no malformation specific to this drug has been reported. We report a case using LEV during pregnancy and left hand absent (acheiria) in the fetus. Keywords: Congenital malformation, Fetal acheiria, Levetiracetam, Antiepileptic drug

Anahtar Kelimeler

• Congenital malformation
• Fetal acheiria
• Levetiracetam
• Antiepileptic drug

Levetirasetam Kullanan Gebede Fetal Sol El Yokluğu: Olgu Sunumu

Öz

Öz: Epilepsi, üreme çağındaki kadınlarda görülen yaygın kronik hastalıklardan biridir. Epileptik nöbet geçirmenin ciddi maternal ve fetal riskleri vardır, bu nedenle gebelikte tedaviye devam etmek gerekir. Konjenital malformasyon (KM) oranları özellikle birinci kuşak antiepileptik kullanımı ile artmaktadır. Levetirasetam (LEV) ise ikinci kuşak antiepileptik olup, teratojenik yan etkileri daha azdır. LEV kullanan gebede KM ile ilgili yayınlar olmasına rağmen, bu ilaca özgü herhangi bir malformasyon bildirilmemiştir. Biz gebeliği boyunca LEV kullanan ve fetüste sol el yokluğu (acheiria) izlenen bir vakayı bildirmekteyiz. Anahtar Kelimeler:Konjenital malformasyon, Fetal el yokluğu, Levetirasetam, Antiepileptik ilaç

Anahtar Kelimeler

• Konjenital malformasyon
• Fetal el yokluğu
• Levetirasetam
• Antiepileptik ilaç

Kaynakça

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