Sinonazal Kitlelerde On Yıllık Retrospektif Histopatolojik Sonuçlarımız

Öz

Amaç: Sinonazal kitle nedeniyle biyopsi alınan veya opere edilen hastaların patoloji sonuçlarını retrospektif olarak yaş, cinsiyet dağılını ve kitlenin tek taraflı mı yoksa iki taraflı mı olduğunu incelemeyi ve bulgularımızı güncel literatür ile karşılaştırmayı ve tartışmayı hedefledik. Yöntem ve Gereçler: Ocak 2014 ile Aralık 2023 tarihleri 362 hastanın histopatolojik sonuçları retrospektif olarak incelendi. Tüm histopatolojik tanılar benign, malign ve neoplastik olmayan olarak 3 gruba ayrıldı. Tek taraflı tutulumlu olgular ile çift taraflı tutulumlu olguların dağılım oranları, yaş ve cinsiyetleri değerlendirildi. Bulgular: Olguların ortalama yaşı 45,9 idi. Çalışmaya dahil edilen hastaların 214’ü (%59) erkek, 148’i (%4) kadındı. En sık görülen histopatolojik tanı 235 vaka ve %65 oranla nazal polipti. Histopataolojik tanılar 298 hastada %82,5 nonneoplastik, 61 (%16.7) hastada benign, ve 3 (%0,8) hastada malign olarak dağılmaktaydı. Tüm hastaların %53,6'sında iki taraflı tutulum vardı. Sonuç: Sinonazal kitlelerin dağılımı açısından literatürde benzer planlanmış çalışmalarla yakın sonuçlar elde ettik. En sık görülen histopatolojik tanı nazal polipti. Çoğu sinonazal kitle benign veya nonneoplastik olarak belirlense de malign kitleler de akılda tutulmalıdır.

Anahtar Kelimeler

• nazal polipozis
• Histopatoloji
• İntranazal kitle
• Antrokoanal polip
• İnverted papillom

Our Ten-Years Retrospective Histopathological Results in Sinonasal Masses

Öz

Objective: We aimed to examine retrospectively the age, gender or whether the mass was single-sided or bilateral in patients who were operated on or biopsied for a sinonasal mass and also to compare and discuss our results with current literature. Material and Methods: The histopathological results of 362 patients who were biopsied or operated due to an intranasal mass between January 2014 and December 2023 were analyzed retrospectively. Pathological results were grouped as benign, non-neoplastic, and malignant. Distribution rates, age and gender, and involvement whether unilateral or bilateral were evaluated. Results: The mean age of the cases was 45.5 years (range: 10-91) Of the patients included in the study, 214 (59%) were male and 148 (4%) were female. Nasal polyp cases prevail among all histopathological lesions with a case number of 235 and a percentage of 65%. 298 out of 362 patients (82.5%) had a non-neoplastic lesion, benign lesions constitute 61 (16.7%) of all histopathological results, and 3 (0.8%) account for a malignant tumor. 53.6% of all patients had bilateral involvement. Conclusion: We obtained approximately the same results with similarly conducted studies in the literature in terms of the distribution of the sinonasal masses. The most frequent histopathological diagnosis was nasal polyp. Most sinonasal masses are recorded to be benign or nonneoplastic however malignancy should also be kept in mind.

Anahtar Kelimeler

• Nasal polyposis
• Histopathology
• Intranasal mass
• Antrochonal polyp
• Inverted papilloma

Kaynakça

1. 1. Zafar U, Khan N, Afroz N, Hasan SA. Clinicopathological study of non- neoplastic lesions of nasal cavity and paranasal sinuses. Indian J Pathol Microbiol 2008; 51(1):26-9.
2. 2. Som PM, Brandwein-Gensler MS, Kassel EE, Genden EM. Tumors and tumor-like conditions of the sinonasal cavities. In: Som PM, Curtin HD, editors. Head and neck imaging. 5. St Louis: Elsevier 2011:253-410.
3. 3. Newton JR, Ah-See KW. A review of nasal polyposis. Ther Clin Risk Manag 2008; 4(2):507-12.
4. 4. Cingi C, Demirbas D, Ural A. Nasal polyposis: an overview of differential diagnosis and treatment. Recent Pat Inflamm Allergy Drug Discov 2011; 5(3): 241-52.
5. 5. Habeşoğlu TE, Habeşoğlu M, Toros ZS, Naiboğlu B, Sürmeli M, Egeli E. Tek taraflı sinonazal polipoid kitlelerde histopatoloji ve neoplastik hastalık için risk faktörleri. Göztepe Tıp Dergisi 2010; 25(2):78-81.
6. 6. Agarwal M, Policeni B. Sinonasal Neoplasms. Semin Roentgenol 2019; 54(3):244-57.
7. 7. Loevner LA, Sonners AI. Imaging of neoplasms of the paranasal sinuses. Neuroimaging Clin N Am 2004; 14(4):625-46.
8. 8. Stevens WW, Schleimer RP, Kern RC. Chronic Rhinosinusitis with Nasal Polyps. J Allergy Clin Immunol Pract 2016; 4(4):565-72.

9. 9. Yaman H, Yilmaz S, Karali E, Guclu E, Ozturk O. Evaluation and management of antrochoanal polyps. Clin Exp Otorhinolaryngol 2010; 3(2):110-4.
10. 10. Gupta R, Moupachi SS, Poorey VK. Sinonasal masses: a retrospective analysis. Indian J Otolaryngol Head Neck Surg 2013; 65(1):52-6.
11. 11. Iziki O, Rouadi S, Abada RL, Roubal M, Mahtar M. Bilateral antrochoanal polyp: report of a new case and systematic review of the literature. J Surg Case Rep 2019; (3):rjz074.
12. 12. Yilmaz YF, Titiz A, Ozcan M, Tezer MS, Ozlugedik S, Unal A. Bilateral antrochoanal polyps in an adult: a case report. B-ENT 2007; 3(2):97-9.
13. 13. Basu SK, Bandyopadhyay SN, Bora H. Bilateral antrochoanal polyps. J Laryngol Otol 2001; 115(7):561-2.
14. 14. Bugter O, Monserez DA, van Zijl FVWJ, Baatenburg de Jong RJ, Hardillo JA. Surgical management of inverted papilloma; a single-center analysis of 247 patients with long follow-up. J Otolaryngol Head Neck Surg 2017; 46(1):67.
15. 15. Katori H, Nozawa A, Tsukuda M. Histopathological parameters of recurrence and malignant transformation in sinonasal inverted papilloma. Acta Otolaryngol 2006; 126(2):214-8.
16. 16. Bist SS, Varshney S, Baunthiyal V, Bhagat S, Kusum A. Clinico-pathological profile of sinonasal masses: An experience in tertiary care hospital of Uttarakhand. Natl J Maxillofac Surg 2012; 3(2):180-6.
17. 17. Kahveci OK, Duran A, Miman MC. Burun İçi Kitlelerde Histopatolojik Sonuçlarımız; 6 Yıllık Retrospektif Çalışma. J Clin Anal Med 2012; 3(3):289-92.