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Cognitive Dysfunction Among Emergency Department Patients Over the Age of 50 Years

Yıl 2021, Cilt: 7 Sayı: 2, 258 - 267, 12.07.2021
https://doi.org/10.53394/akd.958952

Öz

Objective: The aim of this study is to determine the prevalence of cognitive dysfunction among the patients over the age of 50 years who present to the emergency department.
Material and Methods: This cross-sectional study was carried out in the Emergency Department of Akdeniz University Hospital. In a 24-day period, all patients over the age of 50 years who presented to emergency department on weekdays between 08:00 and 18:00 were included in the study. Mini-Mental State Examination (MMSE) was applied to determine the cognitive dycfunction of the patients and threshold score was used as 23/24.
Results: Data of 298 patients were analysed. According to threshold score, cognitive dysfunction was detected in 53.7% of patients. Mild cognitive dycfunction (MMSE: 18-23) was detected in 47.3% of patients. MMSE scores decreaed with advancing age. A significant difference was found between education levels and MMSE scores; MMSE scores decreased as the level of education decreased. MMSE scores of female patients were detected to be significantly lower compared to male patients however significance was detected to arise from the lower education level of female patients.
Conclusion: MMSE scores are significantly affected by age and the level of education of patients over 50 years of age. In order to detect cognitive disorders in the early stage and to make appropriate referrals, it is necessary to conduct the validity and reliability study of MMSE in the emergency department setting.

Kaynakça

  • United Nations, Department of Economic and Social Affairs, Population Division (2013). World Population Ageing 2013. ST/ESA/SER.A/348.
  • Bora Başkara B, Soytutan Çağlar İ, Aygün A, Özdemir TA (Editörler). T.C. Sağlık Bakanlığı Sağlık İstatistikleri Yıllığı 2017. Ankara: T.C. Sağlık Bakanlığı; 2018.
  • Davis LE, King MK, Schultz JS. Disorders of higher cortical function. In: Davis LE, King MK, Schultz JS, eds. Fundemantals of Neurologic Disease. 1st ed. New York: Demos Medical Publishing, 2005:109-22.
  • Selekler K. Alois Alzheimer ve Alzheimer Hastalığı. Türk Geriatri Dergisi 2010; 13 (suppl 3):9-14.
  • Jonker C, Geerlings MI, Schmand B. Are memory complaints predictive for dementia? A review of clinical and population-based studies? Int J Geriatr Psychiatry 2000;15(11):983-91.
  • Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: cilinical characterization and outcome. Arch Neurol 1999; 56(3):303-8.
  • Folstein MF, Folstein S, Mc Hugh PR.”Mini Mental State”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12(3):189-98.
  • Wilber ST, Lofgren SD, Mager TG, Blanda M, Gerson LW. An evaluation of two screening tools for cognitive impairment in older emergency department patients. Acad Emerg Med. 2005; 12(7):612–6.
  • O’Connor DW, Pollitt PA, Treasure FP, Brook CP, Reiss BB: The influence of education, social class and sex on Mini-Mental State scores. Psychol Med 1989, 19(3):771-776.
  • Fabrigoule C, Lechevallier N, Crasborn L, Dartigues JF, Orgogozo JM: Inter-rater reliability of scales and tests used to measure mild cognitive impairment by general practitioners and psychologists. Curr Med Res Opin 2003, 19(7):603-8.
  • Tierney MC, Szalai JP, Dunn E, Geslani D, McDowell I: Prediction of probable Alzheimer disease in patients with symptoms suggestive of memory impairment. Arch Fam Med 2000, 9(6):527-532.
  • Güngen C, Ertan T, Eker E, Yaşar R, Ergin F. Standardize Mini Mental Test’in Türk toplumunda hafif demans tanısında geçerlik ve güvenilirliği. Türk Psikiyatri Dergisi 2002; 13(4):273-81.
  • Sanders AB. The elder patient. In: Tintinalli JE, Kelen GD, Stapczynski JS, eds. Emergency Medicine: A Comprehensive Study Guide. 6th ed. New York: McGraw-Hill Co, 2004:1896-900.
  • The accuracy of the MMSE in detecting cognitive impairment when administered by general practitioners: a prospective observational study. Pezzotti P, Scalmana S, Mastromattei A, Di Lallo D; Progetto Alzheimer Working Group. BMC Fam Pract 2008;9:29.
  • Naughton BJ, Moran MB, Kadah H, Heman-Ackah Y, Longano J. Delirium and other cognitive impairment in older adults in an emergency department. Ann Emerg Med 1995; 25(6):813-7.
  • Gerson LW, Counsell SR, Fontanarosa PB, Smucker WD. Case finding of cognitive impairment in elderly emergency department patients. Ann Emerg Med 1994;23(4):813-7.
  • Hustey FM, Meldon SW. The prevalence and documentation of impaired mental status in elderly emergency patients. Acad Emerg Med 2002; 39(3):248-53.
  • Lobo A, Launer LJ, Fratiglioni L, Andersen K, Di Carlo A, Breteler MM, Copeland JR, Dartigues JF, Jagger C, Martinez-Lage J, Soininen H, Hofman A.. Prevalence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology 2000; 54(11 Suppl 5):S4-9.
  • Çuhadar D, Sertbaş G, Tutkun H. Huzurevinde Yaşayan Yaşlıların Bilişsel İşlev ve Günlük Yaşam Etkinliği Düzeyleri Arasındaki İlişki. Anadolu Psikiyatri Dergisi 2006;7(4):232-9.
  • Karaman Y. Hafif Kognitif Etkilenme Erken Dönem Alzheimer Hastalığı Mıdır? Türk Geriatri Dergisi 2006;9(4):240-9.
  • Crum RM, Anthony JC, Bassett SS, Folstein MF. Population-based norms for the Mini-Mental State Examination by age and educational level. JAMA 1993; 269(18):2386-91.
  • Petersen RC, Doody R, Kurz A, Mohs RC, Morris JC, Rabins PV, Ritchie K, Rossor M, Thal L, Winblad B. Current concepts in mild cognitive impairment. Arch Neurol 2001; 58(12):1985-92.
  • Tierney MC, Szalai JP, Snow WG, Fisher RH, Nores A, Nadon G, Dunn E, St George-Hyslop PH. Prediction of probable Alzheimer’s disease in memory-impaired patients: A prospective longitudinal study. Neurology 1996;46(3):661-5.
  • Geslani DM, Tierney MC, Herrmann N, Szalai JP. Mild cognitive impairment: an operational definition and its conversion rate to Alzheimer’s disease. Dement Geriatr Cogn Disord 2005; 19(5-6):383-9.
  • Yaluğ İ, Alemdar M. Hafif Bilişsel Bozukluk. Türkiye’de Psikiyatri 2006; 8(2):108-14.
  • Maral I, Aslan S, İlhan MN, Yıldırım A, Candansayar S, Bumin MA. Depresyon Yaygınlığı ve Risk Etkenleri: Huzurevinde ve Evde Yaşayan Yaşlılarda Karşılaştırmalı Bir Çalışma. Türk Psikiyatri Dergisi 2001; 12(4):251-60.
  • Evans DA, Funkenstein HH, Albert MS, Scherr PA, Cook NR, Chown MJ, Hebert LE, Hennekens CH, Taylor JO. Prevalence of Alzheimer’s disease in a community population of older persons. Higher than previously reported. JAMA 1989; 262(18):2551-6.
  • Chandra V, Ganguli M, Pandav R, Johnston J, Belle S, DeKosky ST. Prevalence of Alzheimer’s disease and other dementias in rural India: the Indo-US study. Neurology 1998; 51(4):1000-8.
  • Visser PJ, Verhey FR. Mild cognitive impairment as predictor for Alzheimer’s disease in clinical practice: effect of age and diagnostic criteria. Psychol Med 2008; 38(1):113-22.
  • Edland SD, Rocca WA, Petersen RC, Cha RH, Kokmen E. Dementia and Alzheimer disease incidence rates do not vary by sex in Rochester. Minn. Arch Neurol 2002;59(10):1589-93.
  • Bachman DL, Wolf PA, Linn RT, Knoefel JE, Cobb JL, Belanger AJ, White LR, D’Agostino RB. Incidence of dementia and probable Alzheimer’s disease in a general population: the Framingham Study. Neurology 1993; 43(3 Pt 1):515-9.
  • Gatz M, Mortimer JA, Fratiglioni L, Johansson B, Berg S, Andel R, Crowe M, Fiske A, Reynolds CA, Pedersen NL. Accounting for the relationship between low education and dementia: a twin study. Physiol Behav 2007; 92(1-2):232-7.
  • Filley CM, Brownell HH, Albert ML. Education provides no protection against Alzheimer’s disease. Neurology 1985; 35:1781-4.
  • Ott A, Breteler MM, van Harskamp F, Claus JJ, van der Cammen TJ, Grobbee DE, Hofman A. Prevalence of Alzheimer’s disease and vascular dementia: association with education. The Rotterdam study. BMJ 1995;310(6985):970-3.
  • Ngandu T, von Strauss E, Helkala EL, Winblad B, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M. Education and dementia: what lies behind the association? Neurology 2007; 69(14):1442-50.
  • Siuda J, Gorrzkowska A, Opala G, Ochudło S. Vascular risk factors and intensity of cognitive dysfunction in MCI. J Neurol Sci 2007; 257(1-2):202-5.
  • Biessels GJ, Staekenborg S, Brunner E, Brayne C, Scheltens P. Risk of dementia in diabetes mellitus: a systematic review. Lancet Neurol 2006; 5(2):64-74.
  • Cherubini A, Lowenthal DT, Paran E, Mecocci P, Williams LS, Senin U. Hypertension and cognitive function in the elderly. Am J Ther 2007; 14(6):533-54.
  • Seliger SL, Siscovick DS, Stehman-Breen CO, Gillen DL, Fitzpatrick A, Bleyer A, Kuller LH. Moderate renal impairment and risk of dementia among older adults: the Cardiovascular Health Cognition Study. J Am Soc Nephrol 2004; 15(7):1904-11.
  • Kurella M, Chertow GM, Fried LF, Cummings SR, Harris T, Simonsick E, Satterfield S, Ayonayon H, Yaffe K. Chronic kidney disease and cognitive impairment in the elderly: the health, aging, and body composition study. J Am Soc Nephrol 2005; 16(7):2127-33.
  • Fukunishi I, Kitaoka T, Shirai T, Kino K, Kanematsu E, Sato Y. Psychiatric disorders among patients undergoing hemodialysis therapy. Nephron 2002; 91(2):344-7.
  • Paterniti S, Verdier-Taillefer MH, Dufouil C, Alpérovitch A. Depressive symptoms and cognitive decline in elderly people. Longitudinal study. Br J Psychiatry 2002;181(5):406-10.
  • Forsell Y, Palmer K, Fratiglioni L. Psychiatric symptoms/syndromes in elderly persons with mild cognitive impairment. Data from a cross-sectional study. Acta Neurol Scand 2003; 107 (Suppl 179):25-8.
  • Kimmel PL, Cukor D, Cohen SD, Peterson RA. Depression in end-stage renal disease patients: a critical review. Adv Chronic Kidney Dis 2007; 14(4):328-34.
  • Pamuk GE, Harmandar F, Ermantaş N, Harmandar O, Turgut B, Demir M, Vural O. EORTC QLQ-C30 assessment in Turkish patients with hematological malignancies: association with anxiety and depression. Ann Hematol 2008; 87(4):305-10.
  • Dyer AH, Briggs R, Nabeel S, O’Neill D, Kennelly SP. The Abbreviated Mental Test 4 for cognitive screening of older adults presenting to the Emergency Department. Eur J Emerg Med 2017; 24:417-22.
  • Carpenter CR, DesPain B, Keeling TN, Shah M, Rothenberger M. The Six-Item Screener and AD8 for the detection of cognitive impairment in geriatric emergency department patients. Ann Emerg Med. 2011; 57(6):653-61.
  • Carpenter CR1, Banerjee J, Keyes D, Eagles D, Schnitker L, Barbic D, Fowler S, LaMantia MA. Accuracy of Dementia Screening Instruments in Emergency Medicine: A Diagnostic Meta-analysis. Acad Emerg Med 2019;26(2):226-45.

Acil Servise Başvuran 50 Yaş ve Üzeri Hastalarda Bilişsel Fonksiyon Bozukluğu

Yıl 2021, Cilt: 7 Sayı: 2, 258 - 267, 12.07.2021
https://doi.org/10.53394/akd.958952

Öz

Amaç: Bu çalışmanın amacı acil servise başvuran 50 yaş ve üzeri hasta grubunda bilişsel fonksiyon bozukluğunun sıklığını saptamaktır.
Gereç ve Yöntemler: Bu kesitsel çalışma Akdeniz Üniversitesi Hastanesi Acil Servisi’nde yapıldı. 24 günlük bir dönem içinde, hafta içi günlerde 08:00 - 18:00 saatleri arasında acil servise başvuran 50 yaş ve üzerindeki tüm hastalar çalışmaya dâhil edildi. Hastaların bilişsel fonksiyon bozukluğunun tespit edilmesi için Mini-Mental Durum Testi (MMDT) uygulandı ve eşik skor 23/24 olarak kullanıldı.
Bulgular: Toplam 298 hastanın verileri analiz edildi. Eşik skora göre hastaların %53,7’sinde bilişsel fonksiyon bozukluğu olduğu saptandı. Hafif bilişsel bozukluk (MMDT: 18-23) hastaların %47,3’ünde tespit edildi. İlerleyen yaşla birlikte MMDT skorlarının azaldığı belirlendi. Eğitim düzeyleri ile MMDT skorları arasında anlamlı bir farklılık bulundu; eğitim düzeyi azaldıkça MMDT skorlarının azaldığı belirlendi. Kadın hastaların MMDT skorlarının erkek hastalara oranla anlamlı şekilde düşük olduğu tespit edildi, ancak anlamlılığın kadın hastaların eğitim düzeyinin düşük olmasından kaynaklandığı saptandı.
Sonuç: MMDT skorları 50 yaş üstü hastalarda, yaş ve eğitim düzeyinden belirgin şekilde etkilenmektedir. Bilişsel bozuklukların erken dönemde tespit edilebilmesi ve uygun yönlendirmelerin yapılması için MMDT’nin acil servis koşullarındaki geçerlik ve güvenilirlik çalışmasının yapılması gerekmektedir.

Kaynakça

  • United Nations, Department of Economic and Social Affairs, Population Division (2013). World Population Ageing 2013. ST/ESA/SER.A/348.
  • Bora Başkara B, Soytutan Çağlar İ, Aygün A, Özdemir TA (Editörler). T.C. Sağlık Bakanlığı Sağlık İstatistikleri Yıllığı 2017. Ankara: T.C. Sağlık Bakanlığı; 2018.
  • Davis LE, King MK, Schultz JS. Disorders of higher cortical function. In: Davis LE, King MK, Schultz JS, eds. Fundemantals of Neurologic Disease. 1st ed. New York: Demos Medical Publishing, 2005:109-22.
  • Selekler K. Alois Alzheimer ve Alzheimer Hastalığı. Türk Geriatri Dergisi 2010; 13 (suppl 3):9-14.
  • Jonker C, Geerlings MI, Schmand B. Are memory complaints predictive for dementia? A review of clinical and population-based studies? Int J Geriatr Psychiatry 2000;15(11):983-91.
  • Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: cilinical characterization and outcome. Arch Neurol 1999; 56(3):303-8.
  • Folstein MF, Folstein S, Mc Hugh PR.”Mini Mental State”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12(3):189-98.
  • Wilber ST, Lofgren SD, Mager TG, Blanda M, Gerson LW. An evaluation of two screening tools for cognitive impairment in older emergency department patients. Acad Emerg Med. 2005; 12(7):612–6.
  • O’Connor DW, Pollitt PA, Treasure FP, Brook CP, Reiss BB: The influence of education, social class and sex on Mini-Mental State scores. Psychol Med 1989, 19(3):771-776.
  • Fabrigoule C, Lechevallier N, Crasborn L, Dartigues JF, Orgogozo JM: Inter-rater reliability of scales and tests used to measure mild cognitive impairment by general practitioners and psychologists. Curr Med Res Opin 2003, 19(7):603-8.
  • Tierney MC, Szalai JP, Dunn E, Geslani D, McDowell I: Prediction of probable Alzheimer disease in patients with symptoms suggestive of memory impairment. Arch Fam Med 2000, 9(6):527-532.
  • Güngen C, Ertan T, Eker E, Yaşar R, Ergin F. Standardize Mini Mental Test’in Türk toplumunda hafif demans tanısında geçerlik ve güvenilirliği. Türk Psikiyatri Dergisi 2002; 13(4):273-81.
  • Sanders AB. The elder patient. In: Tintinalli JE, Kelen GD, Stapczynski JS, eds. Emergency Medicine: A Comprehensive Study Guide. 6th ed. New York: McGraw-Hill Co, 2004:1896-900.
  • The accuracy of the MMSE in detecting cognitive impairment when administered by general practitioners: a prospective observational study. Pezzotti P, Scalmana S, Mastromattei A, Di Lallo D; Progetto Alzheimer Working Group. BMC Fam Pract 2008;9:29.
  • Naughton BJ, Moran MB, Kadah H, Heman-Ackah Y, Longano J. Delirium and other cognitive impairment in older adults in an emergency department. Ann Emerg Med 1995; 25(6):813-7.
  • Gerson LW, Counsell SR, Fontanarosa PB, Smucker WD. Case finding of cognitive impairment in elderly emergency department patients. Ann Emerg Med 1994;23(4):813-7.
  • Hustey FM, Meldon SW. The prevalence and documentation of impaired mental status in elderly emergency patients. Acad Emerg Med 2002; 39(3):248-53.
  • Lobo A, Launer LJ, Fratiglioni L, Andersen K, Di Carlo A, Breteler MM, Copeland JR, Dartigues JF, Jagger C, Martinez-Lage J, Soininen H, Hofman A.. Prevalence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology 2000; 54(11 Suppl 5):S4-9.
  • Çuhadar D, Sertbaş G, Tutkun H. Huzurevinde Yaşayan Yaşlıların Bilişsel İşlev ve Günlük Yaşam Etkinliği Düzeyleri Arasındaki İlişki. Anadolu Psikiyatri Dergisi 2006;7(4):232-9.
  • Karaman Y. Hafif Kognitif Etkilenme Erken Dönem Alzheimer Hastalığı Mıdır? Türk Geriatri Dergisi 2006;9(4):240-9.
  • Crum RM, Anthony JC, Bassett SS, Folstein MF. Population-based norms for the Mini-Mental State Examination by age and educational level. JAMA 1993; 269(18):2386-91.
  • Petersen RC, Doody R, Kurz A, Mohs RC, Morris JC, Rabins PV, Ritchie K, Rossor M, Thal L, Winblad B. Current concepts in mild cognitive impairment. Arch Neurol 2001; 58(12):1985-92.
  • Tierney MC, Szalai JP, Snow WG, Fisher RH, Nores A, Nadon G, Dunn E, St George-Hyslop PH. Prediction of probable Alzheimer’s disease in memory-impaired patients: A prospective longitudinal study. Neurology 1996;46(3):661-5.
  • Geslani DM, Tierney MC, Herrmann N, Szalai JP. Mild cognitive impairment: an operational definition and its conversion rate to Alzheimer’s disease. Dement Geriatr Cogn Disord 2005; 19(5-6):383-9.
  • Yaluğ İ, Alemdar M. Hafif Bilişsel Bozukluk. Türkiye’de Psikiyatri 2006; 8(2):108-14.
  • Maral I, Aslan S, İlhan MN, Yıldırım A, Candansayar S, Bumin MA. Depresyon Yaygınlığı ve Risk Etkenleri: Huzurevinde ve Evde Yaşayan Yaşlılarda Karşılaştırmalı Bir Çalışma. Türk Psikiyatri Dergisi 2001; 12(4):251-60.
  • Evans DA, Funkenstein HH, Albert MS, Scherr PA, Cook NR, Chown MJ, Hebert LE, Hennekens CH, Taylor JO. Prevalence of Alzheimer’s disease in a community population of older persons. Higher than previously reported. JAMA 1989; 262(18):2551-6.
  • Chandra V, Ganguli M, Pandav R, Johnston J, Belle S, DeKosky ST. Prevalence of Alzheimer’s disease and other dementias in rural India: the Indo-US study. Neurology 1998; 51(4):1000-8.
  • Visser PJ, Verhey FR. Mild cognitive impairment as predictor for Alzheimer’s disease in clinical practice: effect of age and diagnostic criteria. Psychol Med 2008; 38(1):113-22.
  • Edland SD, Rocca WA, Petersen RC, Cha RH, Kokmen E. Dementia and Alzheimer disease incidence rates do not vary by sex in Rochester. Minn. Arch Neurol 2002;59(10):1589-93.
  • Bachman DL, Wolf PA, Linn RT, Knoefel JE, Cobb JL, Belanger AJ, White LR, D’Agostino RB. Incidence of dementia and probable Alzheimer’s disease in a general population: the Framingham Study. Neurology 1993; 43(3 Pt 1):515-9.
  • Gatz M, Mortimer JA, Fratiglioni L, Johansson B, Berg S, Andel R, Crowe M, Fiske A, Reynolds CA, Pedersen NL. Accounting for the relationship between low education and dementia: a twin study. Physiol Behav 2007; 92(1-2):232-7.
  • Filley CM, Brownell HH, Albert ML. Education provides no protection against Alzheimer’s disease. Neurology 1985; 35:1781-4.
  • Ott A, Breteler MM, van Harskamp F, Claus JJ, van der Cammen TJ, Grobbee DE, Hofman A. Prevalence of Alzheimer’s disease and vascular dementia: association with education. The Rotterdam study. BMJ 1995;310(6985):970-3.
  • Ngandu T, von Strauss E, Helkala EL, Winblad B, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M. Education and dementia: what lies behind the association? Neurology 2007; 69(14):1442-50.
  • Siuda J, Gorrzkowska A, Opala G, Ochudło S. Vascular risk factors and intensity of cognitive dysfunction in MCI. J Neurol Sci 2007; 257(1-2):202-5.
  • Biessels GJ, Staekenborg S, Brunner E, Brayne C, Scheltens P. Risk of dementia in diabetes mellitus: a systematic review. Lancet Neurol 2006; 5(2):64-74.
  • Cherubini A, Lowenthal DT, Paran E, Mecocci P, Williams LS, Senin U. Hypertension and cognitive function in the elderly. Am J Ther 2007; 14(6):533-54.
  • Seliger SL, Siscovick DS, Stehman-Breen CO, Gillen DL, Fitzpatrick A, Bleyer A, Kuller LH. Moderate renal impairment and risk of dementia among older adults: the Cardiovascular Health Cognition Study. J Am Soc Nephrol 2004; 15(7):1904-11.
  • Kurella M, Chertow GM, Fried LF, Cummings SR, Harris T, Simonsick E, Satterfield S, Ayonayon H, Yaffe K. Chronic kidney disease and cognitive impairment in the elderly: the health, aging, and body composition study. J Am Soc Nephrol 2005; 16(7):2127-33.
  • Fukunishi I, Kitaoka T, Shirai T, Kino K, Kanematsu E, Sato Y. Psychiatric disorders among patients undergoing hemodialysis therapy. Nephron 2002; 91(2):344-7.
  • Paterniti S, Verdier-Taillefer MH, Dufouil C, Alpérovitch A. Depressive symptoms and cognitive decline in elderly people. Longitudinal study. Br J Psychiatry 2002;181(5):406-10.
  • Forsell Y, Palmer K, Fratiglioni L. Psychiatric symptoms/syndromes in elderly persons with mild cognitive impairment. Data from a cross-sectional study. Acta Neurol Scand 2003; 107 (Suppl 179):25-8.
  • Kimmel PL, Cukor D, Cohen SD, Peterson RA. Depression in end-stage renal disease patients: a critical review. Adv Chronic Kidney Dis 2007; 14(4):328-34.
  • Pamuk GE, Harmandar F, Ermantaş N, Harmandar O, Turgut B, Demir M, Vural O. EORTC QLQ-C30 assessment in Turkish patients with hematological malignancies: association with anxiety and depression. Ann Hematol 2008; 87(4):305-10.
  • Dyer AH, Briggs R, Nabeel S, O’Neill D, Kennelly SP. The Abbreviated Mental Test 4 for cognitive screening of older adults presenting to the Emergency Department. Eur J Emerg Med 2017; 24:417-22.
  • Carpenter CR, DesPain B, Keeling TN, Shah M, Rothenberger M. The Six-Item Screener and AD8 for the detection of cognitive impairment in geriatric emergency department patients. Ann Emerg Med. 2011; 57(6):653-61.
  • Carpenter CR1, Banerjee J, Keyes D, Eagles D, Schnitker L, Barbic D, Fowler S, LaMantia MA. Accuracy of Dementia Screening Instruments in Emergency Medicine: A Diagnostic Meta-analysis. Acad Emerg Med 2019;26(2):226-45.
Toplam 48 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Klinik Tıp Bilimleri
Bölüm Araştırma Makaleleri
Yazarlar

Levent Kuşoğlu Bu kişi benim 0000-0002-4474-4998

Cem Oktay 0000-0001-7993-0566

Özlem Yiğit 0000-0002-3703-7590

Yayımlanma Tarihi 12 Temmuz 2021
Gönderilme Tarihi 21 Mayıs 2020
Yayımlandığı Sayı Yıl 2021 Cilt: 7 Sayı: 2

Kaynak Göster

APA Kuşoğlu, L., Oktay, C., & Yiğit, Ö. (2021). Acil Servise Başvuran 50 Yaş ve Üzeri Hastalarda Bilişsel Fonksiyon Bozukluğu. Akdeniz Tıp Dergisi, 7(2), 258-267. https://doi.org/10.53394/akd.958952