Pathology of Male Breast Lesions: Case Series and Literature Review

Yıl 2021, Cilt: 7 Sayı: 2, 301 - 306, 12.07.2021

Pınar Celepli , Salih Celepli , İrem Bigat Sema Hücümenoğlu

https://doi.org/10.53394/akd.959029

Öz

Objective: Breast cancer is the most common cancer that causes death in women. Male breast cancers
are rare and make up less than 1% of all breast cancers. Therefore, there are very few studies and
no specific male standard protocol has been made. The current treatment approach and prognostic
factors for male breast cancers have been removed from studies on women with breast cancer. In men,
breast cancers are detected at an advanced age and at an advanced stage. Purpose of this study is to
profile breast lesions detected in men and to evaluate cancer cases clinically and pathologically.
Material and Methods: We present our 5-year experience by retrospectively examining male
breast lesions including cases of gynecomastia and breast carcinoma.
Results: Retrospectively between January 2015-January 2020 in our hospital; we detected 43
male breast lesions, including 6 invasive carcinomas, 1 intraductal papilloma, 3 pilomatrixoma, 1
lipomatosis and 32 gynecomastia. Malignant lesions were seen in the 4-8th decades. Malignant lesions
were Grade II and Grade III. Tumour size was determined as the smallest 1.1 cm and the largest 3.0
cm. Different levels of hormone receptor expression were observed in each case.
Conclusion: Since male breast tumours can often be confused with benign diseases, they can be
ignored. Therefore, a more careful approach is required since it can be encountered with breast
tumours that reach advanced stage during diagnosis. Although most of the lesions detected in men
are benign, malignancy should be considered at the forefront in the presence of a mass in the breast
at an advanced age.

Anahtar Kelimeler

Male Breast Carcinoma, Male Breast Lesions, Hormone Profile

Erkek Meme Lezyonlarının Patolojisi: Vaka Serisi ve Literatür Tarama

Öz

Amaç: Meme kanseri, kadınlarda en sık görülen ve en sık ölüme neden olan kanserdir. Erkek meme
kanserleri nadir görülür ve tüm meme kanserlerinin %1’den azını oluşturur. Nadir olması nedeniyle
çok az çalışma vardır ve spesifik erkek standart protokolü yapılamamıştır. Erkek meme kanserleri ile
ilgili güncel tedavi yaklaşımı ve prognostik faktörler meme kanserli kadınlara yapılan çalışmalardan
çıkarılmıştır. Erkeklerde meme kanserleri daha ileri yaşta ve tanı anında ileri evrede saptanmaktadır.
Bu çalışmada amaç erkeklerde saptanan meme lezyonlarının profilini çıkarmak, kanserli olguları
klinik ve patolojik olarak değerlendirmektir.
Gereç ve Yöntemler: Bu çalışmada, jinekomasti ve meme karsinom vakalarını da içeren erkek
meme lezyonlarını retrospektif olarak inceleyerek 5 yıllık deneyimimizi sunuyoruz.
Bulgular: Hastanemiz Ocak 2015-Ocak 2020 tarihleri arasında retrospektif olarak; 6 invaziv
karsinom, 1 intraduktal papillom, 3 pilomatriksoma, 1 lipomatozis ve 32 jinekomasti olmak üzere
toplam 43 erkek meme lezyonu tespit ettik. Malign lezyonlar 4- 8. dekadlarda görüldü. Malign
lezyonlar Grade II ve Grade III olarak izlendi. Tümör boyutu en küçük 1,1cm en büyük 3,0 cm olarak
tespit edildi. Her bir vakada farklı düzeyde hormon reseptör ekspresyonu izlendi.
Sonuç: Erkek meme tümörleri sıklıkla jinekomasti gibi benign hastalıklar ile karışabildiği için, hasta
ve hekimler tarafından göz ardı edilebilir. Bu yüzden tanı konduğu anda ileri evreye ulaşan meme
tümörleri ile karşımıza çıkabildiği için daha dikkatli yaklaşım gerekmektedir. Erkeklerde tespit edilen
lezyonların çoğu benign olmasına karşın ileri yaşta memede ele gelen kitle varlığında malignite ön
planda düşünülmelidir.

Anahtar Kelimeler

Erkek Meme Karsinomu, Erkek Meme Lezyonları, Hormon Profili

Kaynakça

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