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Tip 2 Diabetes Mellituslu Hastaların Bitkisel Destek Kullanım Durumları

Yıl 2021, Cilt: 7 Sayı: 3, 377 - 384, 01.09.2021
https://doi.org/10.53394/akd.979533

Öz

Giriş/Amaç:Kronik seyri ve hastalığın yönetimindeki zorluklar nedeniyle tip 2 diyabetli bireyler tamamlayıcı ve alternatif tedavi yöntemlerine sıklıkla başvurabilmektedir. Bu çalışmada, Tip 2 diyabetli bireylerde bitkisel destek kullanım sıklığı ve bitkisel destek kullanımı ile ilişkili etmenlerin ortaya konulması amaçlanmıştır.
Gereç ve Yöntemler:Tanımlayıcı tipte planlanan araştırmaya, tip 2 diyabet tanısı almış toplam 193 yetişkin birey dahil edilmiştir. Veriler, yapılandırılmış bir anket kullanılarak yüz yüze görüşme yöntemi ile toplanmıştır.
Bulgular:Çalışmaya katılan yaklaşık her üç kişiden birinin (%30,1) diyabetin yönetimi için bitkisel desteklere başvurduğu belirlenmiştir. Bitkisel destek kullanan bireylerin sırasıyla %25,9 ve %24,1?i tarafından kullanıldığı beyan edilen tarçın ve karışım ürünler en çok tercih edilen ürünler olmuştur. Ürünlerin temin edildiği yerlerin başında aktarlar (%50,7) gelmektedir. Bireylerin önemli bir kısmı kullandıkları bitkisel desteğe ilişkin araştırma yapmadığını (%82,8) ve kullandıkları ürün hakkında doktorlarına bilgi vermediğini (%81,0) bildirmiştir. Bitkisel destek kullanan bireylerin %67,3?ünün ürünleri komşu ya da tanıdık tavsiyesi üzerine kullanmaya başladığı kaydedilmiştir. Hem bitkisel destek kullanan (%79,3) hem de kullanmayanların (%67,4) büyük çoğunluğu bitkisel ürünlere yönelik sağlık çalışanlarından bilgi almak istediklerini bildirmişlerdir.
Sonuç:Bu çalışmada diyabetik bireyler arasında bitkisel destek kullanımının yaygın olduğu ortaya konmuştur. Ürünlerin bilinçsiz kullanımını önlemek için sağlık çalışanlarının konuya ilişkin farkındalığının yüksek olmasının gerekli olduğu düşünülmektedir.

Kaynakça

  • 1. International Diabetes Federation (IDF) Diabetes Atlas, 9th edition 2019 (https://www.diabetesatlas.org/en/)
  • 2. Türkiye Endokrinoloji ve Metabolizma Derneği. Diabetes Mellitus ve Komplikasyonlarının Tanı, Tedavi ve İzlem Kılavuzu, 2019.
  • 3. Chang HYA, Wallis M, Tiralongo E. Predictors of complementary and alternative medicine use by people with type 2 diabetes. J Adv Nurs 2012; 68: 1256-66.
  • 4. Chang HY, Wallis M, Tiralongo E. Use of complementary and alternative medicine among people living with diabetes: literature review. J Adv Nurs 2007; 58: 307-19.
  • 5. Cengiz Z, Budak F. Use of complementary medicine among people with diabetes in Eastern Turkey: a descriptive study. Complement Ther Clin Pract 2019; 36: 120-4.
  • 6. Kaynak İ, Polat Ü. Diabetes mellitus'lu hastaların tamamlayıcı ve alternatif tedavileri kullanma durumları ve diyabet tutumları ile ilişkisi. Genel Tıp Dergisi 2017; 27: 56-64.
  • 7. Patade GR, Marita AR. Metformin: A journey from countryside to the bedside. J Obes Metab Res 2014; 1: 127-30.
  • 8. Bailey CJ. Metformin: historical overview. Diabetologia 2017; 60: 1566-76.
  • 9. Gupta RC, Chang D, Nammi S, Bensoussan A, Bilinski K, Roufogalis BD. Interactions between antidiabetic drugs and herbs: an overview of mechanisms of action and clinical implications. Diabetol Metab Syndr 2017; 9: 59.
  • 10. Koyu EB. Diyabette Kullanılan Bitkisel Desteklerin Etkinliği ve Güvenilirliği. Beslenme ve Diyet Dergisi 2019; 47: 110-7.
  • 11. World Health Organization (WHO). The use and interpretation of anthropometry: report of a World Health Organization Expert Committee, Geneva, Switzerland, 1995.
  • 12. Karaman E, Erkin O, Senman S, Yildirim Y. The use of herbal supplements by individuals with diabetes mellitus. J Pak Med Assoc 2018; 68: 587-94.
  • 13. Öztürk S, Gündoğdu YP, Gürsu M, Yamak M, Özkan O, Şar F, Yenigün M, Kazancıoğlu R. Use of herbal products in type 2 diabetic patients. The Medical Bulletin of Haseki 2015; 53: 214-9.
  • 14. Pınar N, Topaloğlu M, Özsan M, Özer C, Alp H. Hatay ilinde üniversite hastanesi endokrin polikliniğine başvuran diyabet hastalarının bitkisel ürün kullanımı. Konuralp Tıp Dergisi 2017; 9: 202-6.
  • 15. Welz AN, Emberger-Klein A, Menrad K. Why people use herbal medicine: insights from a focus-group study in Germany. BMC Complement Altern Med 2018; 18: 92.
  • 16. Azizi-Fini I, Adib-Hajbaghery M, Gharehboghlou Z. Herbal medicine use among patients with type 2 diabetes in Kashan, Iran, 2015. Eur J Integr Med 2016; 8: 570-5.
  • 17. Yıldırım DI, Marakoğlu K. Complementary and alternative medicine use amongst Turkish type 2 diabetic patients: a cross-sectional study. Complement Ther Med 2018; 41: 41-6.
  • 18. Selçuk Tosun A, Zincir H, Eliş E. Complementary and alternative medicine use and self-efficacy level in Turkish adults with type 2 diabetes mellitus. Cukurova Med J 2019; 44: 309-18.
  • 19. Fabian E, Töscher S, Elmadfa I, Pieber TR. Use of complementary and alternative medicine supplements in patients with diabetes mellitus. Ann Nutr Metab 2011; 58: 101-8.
  • 20. Candar A, Demirci H, Baran AK, Akpınar Y. The association between quality of life and complementary and alternative medicine use in patients with diabetes mellitus. Complement Ther Clin Pract 2018; 31: 1-6.
  • 21. Alqathama A, Alluhiabi G, Baghdadi H, Aljahani L, Khan O, Jabal S, Makkawi S, Alhomoud F. Herbal medicine from the perspective of type II diabetic patients and physicians: what is the relationship? BMC Complement Med Ther 2020; 20: 65.
  • 22. Deyno S, Eneyew K, Seyfe S, Tuyiringire N, Peter EL, Muluye RA, Tolo CU, Ogwang PE. Efficacy and safety of cinnamon in type 2 diabetes mellitus and pre-diabetes patients: a meta-analysis and meta-regression. Diabetes Res Clin Pract 2019; 156: 107815.
  • 23. Ilhan M, Demir B, Yuksel S, Çataklı SA, Yıldız RS, Karaman O, Taşan E. The use of complementary medicine in patients with diabetes. North Clin Istanb 2016; 3: 34-8.
  • 24. Kaatabi H, Bamosa AO, Badar A, Al-Elq A, Abou-Hozaifa B, Lebda F, Al-Khadra A, Al-Almaie S. Nigella sativa improves glycemic control and ameliorates oxidative stress in patients with type 2 diabetes mellitus: placebo controlled participant blinded clinical trial. PloS One 2015; 10: e0113486.
  • 25. Bamosa AO, Kaatabi H, Lebdaa FM, Elq AM, Al-Sultanb A. Effect of Nigella sativa seeds on the glycemic control of patients with type 2 diabetes mellitus. Indian J Physiol Pharmacol 2010; 54: 344-54.
  • 26. Bilal A, Masud T, Uppal AM, Naveed AK. Effects of Nigella sativa oil on some blood parameters in type 2 diabetes mellitus patients. Asian Journal of Chemistry. 2009; 21: 5373-81.
  • 27. El-Shamy KA, Mosa MMA, El-Nabarawy SK, El-Qattan GM. Effect of Nigella sativa tea in type 2-diabetic patients as regards glucose homeostasis, liver and kidney functions. J Appl Sci Res 2011; 7: 2524-34.
  • 28. Arslan E, Sayin S, Demirbas S, Cakar M, Somak NG, Yesilkaya S, Sağlam K. A case study report of acute renal failure associated with Nigella sativa in a diabetic patient. J Integr Med 2013; 11: 64-6.
  • 29. Bamosa A. Nigella sativa is a safe herbal product. J Integr Med 2014; 12: 66.
  • 30. Abunab H, Dator WL, Hawamdeh S. Effect of olive leaf extract on glucose levels in diabetes‐induced rats: a systematic review and meta‐analysis. J Diabetes 2017; 9: 947-57.
  • 31. Cam ME, Hazar-Yavuz AN, Yildiz S, Ertas B, Ayaz Adakul B, Taskin T, Alan S, Kabasakal L. The methanolic extract of Thymus praecox subsp. skorpilii var. skorpilii restores glucose homeostasis, ameliorates insulin resistance and improves pancreatic β-cell function on streptozotocin/nicotinamide-induced type 2 diabetic rats. J Ethnopharmacol 2019; 231: 29-38.
  • 32. Soliman MM, Nassan MA, Ismail TA. Origanum majoranum extract modulates gene expression, hepatic and renal changes in a rat model of type 2 diabetes. Iran J Pharm Res Suppl 2016; 15: 45-54.
  • 33. Araki R, Fujie K, Yuine N, Watabe Y, Nakata Y, Suzuki H, Isoda H, Hashimoto K. Olive leaf tea is beneficial for lipid metabolism in adults with prediabetes: an exploratory randomized controlled trial. Nutr Res 2019; 67: 60-6.
  • 34. de Bock M, Derraik JGB, Brennan CM, Biggs JB, Morgan PE, Hodgkinson SC, Hofman PL, Cutfield WS. Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: a randomized, placebo-controlled, crossover trial. PloS One 2013; 8: e57622.
  • 35. Florentin M, Liberopoulos E, Elisaf MS, Tsimihodimos V. No effect of fenugreek, bergamot and olive leaf extract on glucose homeostasis in patients with prediabetes: a randomized double-blind placebo-controlled study. Arch Med Sci Atheroscler Dis 2019; 4: 162-66.
  • 36. Bozdemir Ç. Türkiye’de yetişen kekik türleri, ekonomik önemi ve kullanım alanları. Yüzüncü Yıl Üniversitesi Tarım Bilimleri Dergisi 2019; 29: 583-94.
  • 37. Soner BC, Sahin AS, Sahin TK. A survey of Turkish hospital patients’ use of herbal medicine. Eur J Integr Med 2013; 5: 547-52.
  • 38. Martins RR, Duarte Farias A, Russel Martins R, Gouveia Oliveira A. Influence of the use of medicinal plants in medication adherence in elderly people. Int J Clin Pract 2016; 70: 254-60.
  • 39. Ezuruike U, Prieto JM. Assessment of potential herb-drug interactions among Nigerian adults with type-2 diabetes. Front Pharmacol 2016; 7: 248.
  • 40. Amaeze OU, Aderemi-Williams RI, Ayo-Vaughan MA, Ogundemuren DA, Ogunmola DS, Anyika EN. Herbal medicine use among type 2 diabetes mellitus patients in Nigeria: understanding the magnitude and predictors of use. Int J Clin Pharm 2018; 40: 580-8.
  • 41. Kamel FO, Magadmi RM, Hagras MM, Magadmi B, AlAhmad RA. Knowledge, attitude, and beliefs toward traditional herbal medicine use among diabetics in Jeddah Saudi Arabia. Complement Ther Clin Pract 2017; 29: 207-12.
  • 42. Vickers KA, Jolly KB, Greenfield SM. Herbal medicine: women's views, knowledge and interaction with doctors: a qualitative study. BMC Complement Altern Med 2006; 6: 40.

Herbal Supplement Use among Patients with Type 2 Diabetes Mellitus

Yıl 2021, Cilt: 7 Sayı: 3, 377 - 384, 01.09.2021
https://doi.org/10.53394/akd.979533

Öz

Objective:Due to its chronic course and the difficulties in the management of disease, individuals with type 2 diabetes may frequently use complementary and alternative therapies. The aim of this study was to investigate the frequency of herbal supplement use and factors associated with it in individuals with type 2 diabetes.
Methods:A total of 193 adults diagnosed with type 2 diabetes was included in this descriptive study. Data were collected with face to face interview method using a structured questionnaire.
Results:It was detected that approximately one third of people (30.1%) participating in this study used herbal supplements in diabetes management. Cinnamon and mixed products, used respectively by 25.9% and 24.1% of herbal supplement users, were the most preferred products. The products were usually purchased from herbalists (50.7%). Majority of the individuals reported that they did not make a research for the product (82.8%) and did not give information to their doctors about the product they use (81.0%). Among 67.3% of the herbal supplement user indicated that they started to use the products with the recommendation of neighbors or acquaintances. Both the majority of the herbal product users (79.3%) and non-users (67.4%) stated that they want to get information from healthcare professionals for herbal products.
Conclusion:This study revealed that the use of herbal supplements is common among individuals with type 2 diabetes. It is considered that health professionals should be aware of the issue in order to prevent misuse of the products.

Kaynakça

  • 1. International Diabetes Federation (IDF) Diabetes Atlas, 9th edition 2019 (https://www.diabetesatlas.org/en/)
  • 2. Türkiye Endokrinoloji ve Metabolizma Derneği. Diabetes Mellitus ve Komplikasyonlarının Tanı, Tedavi ve İzlem Kılavuzu, 2019.
  • 3. Chang HYA, Wallis M, Tiralongo E. Predictors of complementary and alternative medicine use by people with type 2 diabetes. J Adv Nurs 2012; 68: 1256-66.
  • 4. Chang HY, Wallis M, Tiralongo E. Use of complementary and alternative medicine among people living with diabetes: literature review. J Adv Nurs 2007; 58: 307-19.
  • 5. Cengiz Z, Budak F. Use of complementary medicine among people with diabetes in Eastern Turkey: a descriptive study. Complement Ther Clin Pract 2019; 36: 120-4.
  • 6. Kaynak İ, Polat Ü. Diabetes mellitus'lu hastaların tamamlayıcı ve alternatif tedavileri kullanma durumları ve diyabet tutumları ile ilişkisi. Genel Tıp Dergisi 2017; 27: 56-64.
  • 7. Patade GR, Marita AR. Metformin: A journey from countryside to the bedside. J Obes Metab Res 2014; 1: 127-30.
  • 8. Bailey CJ. Metformin: historical overview. Diabetologia 2017; 60: 1566-76.
  • 9. Gupta RC, Chang D, Nammi S, Bensoussan A, Bilinski K, Roufogalis BD. Interactions between antidiabetic drugs and herbs: an overview of mechanisms of action and clinical implications. Diabetol Metab Syndr 2017; 9: 59.
  • 10. Koyu EB. Diyabette Kullanılan Bitkisel Desteklerin Etkinliği ve Güvenilirliği. Beslenme ve Diyet Dergisi 2019; 47: 110-7.
  • 11. World Health Organization (WHO). The use and interpretation of anthropometry: report of a World Health Organization Expert Committee, Geneva, Switzerland, 1995.
  • 12. Karaman E, Erkin O, Senman S, Yildirim Y. The use of herbal supplements by individuals with diabetes mellitus. J Pak Med Assoc 2018; 68: 587-94.
  • 13. Öztürk S, Gündoğdu YP, Gürsu M, Yamak M, Özkan O, Şar F, Yenigün M, Kazancıoğlu R. Use of herbal products in type 2 diabetic patients. The Medical Bulletin of Haseki 2015; 53: 214-9.
  • 14. Pınar N, Topaloğlu M, Özsan M, Özer C, Alp H. Hatay ilinde üniversite hastanesi endokrin polikliniğine başvuran diyabet hastalarının bitkisel ürün kullanımı. Konuralp Tıp Dergisi 2017; 9: 202-6.
  • 15. Welz AN, Emberger-Klein A, Menrad K. Why people use herbal medicine: insights from a focus-group study in Germany. BMC Complement Altern Med 2018; 18: 92.
  • 16. Azizi-Fini I, Adib-Hajbaghery M, Gharehboghlou Z. Herbal medicine use among patients with type 2 diabetes in Kashan, Iran, 2015. Eur J Integr Med 2016; 8: 570-5.
  • 17. Yıldırım DI, Marakoğlu K. Complementary and alternative medicine use amongst Turkish type 2 diabetic patients: a cross-sectional study. Complement Ther Med 2018; 41: 41-6.
  • 18. Selçuk Tosun A, Zincir H, Eliş E. Complementary and alternative medicine use and self-efficacy level in Turkish adults with type 2 diabetes mellitus. Cukurova Med J 2019; 44: 309-18.
  • 19. Fabian E, Töscher S, Elmadfa I, Pieber TR. Use of complementary and alternative medicine supplements in patients with diabetes mellitus. Ann Nutr Metab 2011; 58: 101-8.
  • 20. Candar A, Demirci H, Baran AK, Akpınar Y. The association between quality of life and complementary and alternative medicine use in patients with diabetes mellitus. Complement Ther Clin Pract 2018; 31: 1-6.
  • 21. Alqathama A, Alluhiabi G, Baghdadi H, Aljahani L, Khan O, Jabal S, Makkawi S, Alhomoud F. Herbal medicine from the perspective of type II diabetic patients and physicians: what is the relationship? BMC Complement Med Ther 2020; 20: 65.
  • 22. Deyno S, Eneyew K, Seyfe S, Tuyiringire N, Peter EL, Muluye RA, Tolo CU, Ogwang PE. Efficacy and safety of cinnamon in type 2 diabetes mellitus and pre-diabetes patients: a meta-analysis and meta-regression. Diabetes Res Clin Pract 2019; 156: 107815.
  • 23. Ilhan M, Demir B, Yuksel S, Çataklı SA, Yıldız RS, Karaman O, Taşan E. The use of complementary medicine in patients with diabetes. North Clin Istanb 2016; 3: 34-8.
  • 24. Kaatabi H, Bamosa AO, Badar A, Al-Elq A, Abou-Hozaifa B, Lebda F, Al-Khadra A, Al-Almaie S. Nigella sativa improves glycemic control and ameliorates oxidative stress in patients with type 2 diabetes mellitus: placebo controlled participant blinded clinical trial. PloS One 2015; 10: e0113486.
  • 25. Bamosa AO, Kaatabi H, Lebdaa FM, Elq AM, Al-Sultanb A. Effect of Nigella sativa seeds on the glycemic control of patients with type 2 diabetes mellitus. Indian J Physiol Pharmacol 2010; 54: 344-54.
  • 26. Bilal A, Masud T, Uppal AM, Naveed AK. Effects of Nigella sativa oil on some blood parameters in type 2 diabetes mellitus patients. Asian Journal of Chemistry. 2009; 21: 5373-81.
  • 27. El-Shamy KA, Mosa MMA, El-Nabarawy SK, El-Qattan GM. Effect of Nigella sativa tea in type 2-diabetic patients as regards glucose homeostasis, liver and kidney functions. J Appl Sci Res 2011; 7: 2524-34.
  • 28. Arslan E, Sayin S, Demirbas S, Cakar M, Somak NG, Yesilkaya S, Sağlam K. A case study report of acute renal failure associated with Nigella sativa in a diabetic patient. J Integr Med 2013; 11: 64-6.
  • 29. Bamosa A. Nigella sativa is a safe herbal product. J Integr Med 2014; 12: 66.
  • 30. Abunab H, Dator WL, Hawamdeh S. Effect of olive leaf extract on glucose levels in diabetes‐induced rats: a systematic review and meta‐analysis. J Diabetes 2017; 9: 947-57.
  • 31. Cam ME, Hazar-Yavuz AN, Yildiz S, Ertas B, Ayaz Adakul B, Taskin T, Alan S, Kabasakal L. The methanolic extract of Thymus praecox subsp. skorpilii var. skorpilii restores glucose homeostasis, ameliorates insulin resistance and improves pancreatic β-cell function on streptozotocin/nicotinamide-induced type 2 diabetic rats. J Ethnopharmacol 2019; 231: 29-38.
  • 32. Soliman MM, Nassan MA, Ismail TA. Origanum majoranum extract modulates gene expression, hepatic and renal changes in a rat model of type 2 diabetes. Iran J Pharm Res Suppl 2016; 15: 45-54.
  • 33. Araki R, Fujie K, Yuine N, Watabe Y, Nakata Y, Suzuki H, Isoda H, Hashimoto K. Olive leaf tea is beneficial for lipid metabolism in adults with prediabetes: an exploratory randomized controlled trial. Nutr Res 2019; 67: 60-6.
  • 34. de Bock M, Derraik JGB, Brennan CM, Biggs JB, Morgan PE, Hodgkinson SC, Hofman PL, Cutfield WS. Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: a randomized, placebo-controlled, crossover trial. PloS One 2013; 8: e57622.
  • 35. Florentin M, Liberopoulos E, Elisaf MS, Tsimihodimos V. No effect of fenugreek, bergamot and olive leaf extract on glucose homeostasis in patients with prediabetes: a randomized double-blind placebo-controlled study. Arch Med Sci Atheroscler Dis 2019; 4: 162-66.
  • 36. Bozdemir Ç. Türkiye’de yetişen kekik türleri, ekonomik önemi ve kullanım alanları. Yüzüncü Yıl Üniversitesi Tarım Bilimleri Dergisi 2019; 29: 583-94.
  • 37. Soner BC, Sahin AS, Sahin TK. A survey of Turkish hospital patients’ use of herbal medicine. Eur J Integr Med 2013; 5: 547-52.
  • 38. Martins RR, Duarte Farias A, Russel Martins R, Gouveia Oliveira A. Influence of the use of medicinal plants in medication adherence in elderly people. Int J Clin Pract 2016; 70: 254-60.
  • 39. Ezuruike U, Prieto JM. Assessment of potential herb-drug interactions among Nigerian adults with type-2 diabetes. Front Pharmacol 2016; 7: 248.
  • 40. Amaeze OU, Aderemi-Williams RI, Ayo-Vaughan MA, Ogundemuren DA, Ogunmola DS, Anyika EN. Herbal medicine use among type 2 diabetes mellitus patients in Nigeria: understanding the magnitude and predictors of use. Int J Clin Pharm 2018; 40: 580-8.
  • 41. Kamel FO, Magadmi RM, Hagras MM, Magadmi B, AlAhmad RA. Knowledge, attitude, and beliefs toward traditional herbal medicine use among diabetics in Jeddah Saudi Arabia. Complement Ther Clin Pract 2017; 29: 207-12.
  • 42. Vickers KA, Jolly KB, Greenfield SM. Herbal medicine: women's views, knowledge and interaction with doctors: a qualitative study. BMC Complement Altern Med 2006; 6: 40.
Toplam 42 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Klinik Tıp Bilimleri
Bölüm Araştırma Makaleleri
Yazarlar

Ezgi Bellikci-koyu Bu kişi benim 0000-0001-5279-2394

Banu Pınar Şarer Yürekli Bu kişi benim 0000-0003-1809-2655

Nilüfer Özdemir Bu kişi benim 0000-0002-0719-988X

Zehra Büyüktuncer Bu kişi benim 0000-0002-2039-8568

Yayımlanma Tarihi 1 Eylül 2021
Gönderilme Tarihi 3 Temmuz 2020
Yayımlandığı Sayı Yıl 2021 Cilt: 7 Sayı: 3

Kaynak Göster

APA Bellikci-koyu, E., Şarer Yürekli, B. P., Özdemir, N., Büyüktuncer, Z. (2021). Tip 2 Diabetes Mellituslu Hastaların Bitkisel Destek Kullanım Durumları. Akdeniz Tıp Dergisi, 7(3), 377-384. https://doi.org/10.53394/akd.979533