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Preterm Doğum Sonrası Merkezi Kornea Kalınlık ve Büyüme Parametreleri Arasındaki İlişki

Yıl 2022, Cilt: 8 Sayı: 1, 28 - 32, 01.01.2022
https://doi.org/10.53394/akd.1037438

Öz

ÖZ
Giriş/Amaç: Prematüre doğan çocuklarda santral kornea kalınlığını ölçmek ve preterm doğumu takip eden 3 ay boyunca merkezi kornea kalınlığı ile büyüme değerleri arasındaki ilişkiyi karşılaştırmak.
Gereç ve Yöntemler: Bu ileriye dönük çalışmada preterm doğumu takiben 32 çocukta 3 ay boyunca aylık aralıklarla santral kornea kalınlığı, baş çevresi, vücut uzunluğu ve vücut ağırlığı ölçümleri yapıldı. Santral kornea kalınlığı ölçümleri ultrasonik pakimetre cihazı kullanılarak yapıldı. İlk santral kornea kalınlığı ölçümleri doğumdan sonraki 24 - 48 saat içerisinde yapıldı. Baş çevresi, vücut uzunluğu ve vücut ağırlığı ölçümleri yenidoğan uzmanı tarafından doğumdan sonraki 24 saat içinde yapıldı. Tüm ölçümler 1. Ayda, 2. Ayda ve 3. Ayda aynı şekilde gerçekleştirildi.
Bulgular: Çalışmada 18 kız (%56,2) ve 14 erkek (%43,8) bebek vardı. Ortalama doğum haftası ve ağırlığı sırasıyla 27,8 hafta ve 1042±309,9 g idi. Ortalama baş çevresi ve vücut uzunluğu sırasıyla 26,2 cm ve 36,3 cm idi. Doğumda ortalama merkezi kornea kalınlığı 666,03±92,6 µm idi. Çalışma sırasında merkezi kornea kalınlığı önemli ölçüde azaldı (p<0.001). Baş çevresi, vücut uzunluğu ve vücut ağırlığı doğumdan sonra önemli artışlar gösterdi (p<0.001 hepsi için). Birinci ay ile 2. ay arasında santral kornea kalınlığındaki değişim ile vücut uzunluğundaki değişim arasında anlamlı bir negatif korelasyon vardı.
Sonuç: Bu çalışmada, prematüre bebeklerde kornea kalınlığındaki azalmanın, yaşamın erken evrelerinde vücut uzunluğundaki değişikliklerle ters ilişkili olduğu bulunmuştur.
Anahtar Sözcükler: Vücut uzunluğu, Vücut ağırlığı, Merkezi kornea kalınlığı, Baş çevresi ölçümü, Prematüre

Kaynakça

  • 1. Autzen T, Bjørnstrøm L. Central corneal thickness in premature babies. Acta Ophthalmol (Copenh). 1991; 69(2):251-252.
  • 2. Kirwan C, O'Keefe M, Fitzsimon S. Central corneal thickness and corneal diameter in premature infants. Acta Ophthalmol Scand 2005; 83(6):751-753.
  • 3. Uva MG, Reibaldi M, Longo A, et al. Intraocular pressure and central corneal thickness in premature and full-term newborns. J AAPOS 2011; 15(4):367-369.
  • 4. Sehrawat P, Beri S, Garg R, Datta V, Shandil A. Central corneal thickness and corneal diameter in preterm and term newborns and preterm neonates at term. Indian J Ophthalmol 2019; 67(10):1575-1578.
  • 5. Bielemeyer M, Rothschild MA, Schmolling JC, Eifinger F, Banaschak S. Length, weight and head circumference as reliable signs of maturity in a modern German birth collective. Forensic Sci Int 2018; 293:17-23.
  • 6. Rushood AA, Zahrani MH, Khamis A, Rushood AA. Central corneal thickness in full-term Saudi newborns. Acta Ophthalmol 2012; 90(5):e355-e358.
  • 7. Jethani J, Shah K, Jethani M. Evaluating the change in central corneal thickness in neonates (term and preterm) in Indian population and the factors affecting it. Indian journal of ophthalmology 2015; 63(6):501-503.
  • 8. De Silva S, Parentin F, Michieletto P, Pensiero S. Corneal curvature and thickness development in premature infants. J Pediatr Ophthalmol Strabismus 2011; 48(1):25-29.
  • 9. Erginturk Acar D, Acar U, Ozdemir O, Tunay ZO. Determination of normal values of intraocular pressure and central corneal thickness in healthy premature infants-a prospective longitudinal study. J AAPOS 2016; 20(3):239-242.
  • 10. Remón L, Cristóbal JA, Castillo J, Palomar T, Palomar A, Pérez J. Central and peripheral corneal thickness in full-term newborns by ultrasonic pachymetry. Invest Ophthalmol Vis Sci 1992; 33(11):3080-3.
  • 11. Quantock AJ, Young RD. Development of the corneal stroma, and the collagen-proteoglycan associations that help define its structure and function. Dev Dyn 2008; 237(10):2607-2621.
  • 12. Latal-Hajnal B, von Siebenthal K, Kovari H, Bucher HU, Largo RH. Postnatal growth in VLBW infants: significant association with neurodevelopmental outcome. J Pediatr 2003; 143(2):163-170.
  • 13. Giannì ML, Roggero P, Liotto N, Amato O. Postnatal catch-up fat after late preterm birth. Pediatr Res 2012; 72(6):637-640.
  • 14. Roggero P, Giannì ML, Orsi A, et al. Quality of growth in exclusively breast-fed infants in the first six months of life: an Italian study. Pediatr Res 2010; 68(6):542-544.
  • 15. Nash A, Dunn M, Asztalos E, Corey M, Mulvihill-Jory B, O'Connor DL. Pattern of growth of very low birth weight preterm infants, assessed using the WHO Growth Standards, is associated with neurodevelopment. Appl Physiol Nutr Metab 2011; 36(4):562-569.
  • 16. Kıvanç SA, Akova Budak B, Olcaysü OO. Association of Birth Parameters With Corneal Thickness in Prematurely Born and Full-Term School-Aged Children. Cornea 2016; 35(5):634-7.
  • 17. Pereira-da-Silva L, Virella D, Fusch C. Nutritional Assessment in Preterm Infants: A Practical Approach in the NICU. Nutrients 2019; 11(9):1999.
  • 18. Daneault A, Prawitt J, Fabien Soulé V, Coxam V, Wittrant Y. Biological effect of hydrolyzed collagen on bone metabolism. Crit Rev Food Sci Nutr 2017; 57(9):1922-1937.
  • 19. Kirsch T, von der Mark K. Remodelling of collagen types I, II and X and calcification of human fetal cartilage. Bone Miner 1992; 18(2):107-117.

Association Between Central Corneal Thickness and Growth Parameters Following Preterm

Yıl 2022, Cilt: 8 Sayı: 1, 28 - 32, 01.01.2022
https://doi.org/10.53394/akd.1037438

Öz

ABSTRACT
Objective: To investigate central corneal thickness in prematurely born children and to evaluate the association between central corneal thickness and growth pattern during 3 months following preterm birth.
Methods: In this prospective study, central corneal thickness, head circumference, body length and body weight measurements were performed in 32 infants at monthly intervals during the first 3 months following preterm birth. Central corneal thickness measurements were performed by using an ultrasonic pachymetry. Initial central corneal thickness measurements were performed 24 – 48 hours after delivery. The head circumference, body length and body weight measurements were performed within 24 hours following birth by a neonatologist. All measurements were carried out at 1st month, 2nd month and 3rd month in the same manner.
Results: There were 18 female (56.2%) and 14 male (43.8%) infants. The mean gestational age and body weight at birth were 27.8 weeks and 1042±309.9 g, respectively. The mean head circumference and body length at birth were 26.2 cm and 36.3 cm, respectively. Mean central corneal thickness at birth was 666.03±92.6 µm. Central corneal thickness significantly decreased during the study period (p<0.001). Head circumference, body length and body weight showed significant increases following birth (p<0.001 for each). There was a significant negative correlation of central corneal thickness change with the body length change between 1st month and 2nd month (p<0.05).
Conclusion:In this study, decrease of corneal thickness in prematurely born infants was found to be inversely correlated to body length alterations in early months of life.
Key Words: Body length, Body weight, Central corneal thickness, Head circumference measurement, Premature

Kaynakça

  • 1. Autzen T, Bjørnstrøm L. Central corneal thickness in premature babies. Acta Ophthalmol (Copenh). 1991; 69(2):251-252.
  • 2. Kirwan C, O'Keefe M, Fitzsimon S. Central corneal thickness and corneal diameter in premature infants. Acta Ophthalmol Scand 2005; 83(6):751-753.
  • 3. Uva MG, Reibaldi M, Longo A, et al. Intraocular pressure and central corneal thickness in premature and full-term newborns. J AAPOS 2011; 15(4):367-369.
  • 4. Sehrawat P, Beri S, Garg R, Datta V, Shandil A. Central corneal thickness and corneal diameter in preterm and term newborns and preterm neonates at term. Indian J Ophthalmol 2019; 67(10):1575-1578.
  • 5. Bielemeyer M, Rothschild MA, Schmolling JC, Eifinger F, Banaschak S. Length, weight and head circumference as reliable signs of maturity in a modern German birth collective. Forensic Sci Int 2018; 293:17-23.
  • 6. Rushood AA, Zahrani MH, Khamis A, Rushood AA. Central corneal thickness in full-term Saudi newborns. Acta Ophthalmol 2012; 90(5):e355-e358.
  • 7. Jethani J, Shah K, Jethani M. Evaluating the change in central corneal thickness in neonates (term and preterm) in Indian population and the factors affecting it. Indian journal of ophthalmology 2015; 63(6):501-503.
  • 8. De Silva S, Parentin F, Michieletto P, Pensiero S. Corneal curvature and thickness development in premature infants. J Pediatr Ophthalmol Strabismus 2011; 48(1):25-29.
  • 9. Erginturk Acar D, Acar U, Ozdemir O, Tunay ZO. Determination of normal values of intraocular pressure and central corneal thickness in healthy premature infants-a prospective longitudinal study. J AAPOS 2016; 20(3):239-242.
  • 10. Remón L, Cristóbal JA, Castillo J, Palomar T, Palomar A, Pérez J. Central and peripheral corneal thickness in full-term newborns by ultrasonic pachymetry. Invest Ophthalmol Vis Sci 1992; 33(11):3080-3.
  • 11. Quantock AJ, Young RD. Development of the corneal stroma, and the collagen-proteoglycan associations that help define its structure and function. Dev Dyn 2008; 237(10):2607-2621.
  • 12. Latal-Hajnal B, von Siebenthal K, Kovari H, Bucher HU, Largo RH. Postnatal growth in VLBW infants: significant association with neurodevelopmental outcome. J Pediatr 2003; 143(2):163-170.
  • 13. Giannì ML, Roggero P, Liotto N, Amato O. Postnatal catch-up fat after late preterm birth. Pediatr Res 2012; 72(6):637-640.
  • 14. Roggero P, Giannì ML, Orsi A, et al. Quality of growth in exclusively breast-fed infants in the first six months of life: an Italian study. Pediatr Res 2010; 68(6):542-544.
  • 15. Nash A, Dunn M, Asztalos E, Corey M, Mulvihill-Jory B, O'Connor DL. Pattern of growth of very low birth weight preterm infants, assessed using the WHO Growth Standards, is associated with neurodevelopment. Appl Physiol Nutr Metab 2011; 36(4):562-569.
  • 16. Kıvanç SA, Akova Budak B, Olcaysü OO. Association of Birth Parameters With Corneal Thickness in Prematurely Born and Full-Term School-Aged Children. Cornea 2016; 35(5):634-7.
  • 17. Pereira-da-Silva L, Virella D, Fusch C. Nutritional Assessment in Preterm Infants: A Practical Approach in the NICU. Nutrients 2019; 11(9):1999.
  • 18. Daneault A, Prawitt J, Fabien Soulé V, Coxam V, Wittrant Y. Biological effect of hydrolyzed collagen on bone metabolism. Crit Rev Food Sci Nutr 2017; 57(9):1922-1937.
  • 19. Kirsch T, von der Mark K. Remodelling of collagen types I, II and X and calcification of human fetal cartilage. Bone Miner 1992; 18(2):107-117.
Toplam 19 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri
Bölüm Araştırma Makaleleri
Yazarlar

Gokhan Celık Bu kişi benim 0000-0003-2111-0420

Murat Gunay Bu kişi benim 0000-0002-8874-1473

Osman Kızılay Bu kişi benim 0000-0002-0948-3550

Abdulhamit Tüten Bu kişi benim 0000-0002-0024-8458

Yayımlanma Tarihi 1 Ocak 2022
Gönderilme Tarihi 28 Aralık 2020
Yayımlandığı Sayı Yıl 2022 Cilt: 8 Sayı: 1

Kaynak Göster

Vancouver Celık G, Gunay M, Kızılay O, Tüten A. Association Between Central Corneal Thickness and Growth Parameters Following Preterm. Akd Tıp D. 2022;8(1):28-32.