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İntraoperatif Sıvı Yönetiminin Değerlendirilmesi

Yıl 2022, Cilt: 8 Sayı: 1, 33 - 41, 01.01.2022
https://doi.org/10.53394/akd.1037455

Öz

ÖZ
Giriş/Amaç:Büyük cerrahi işlemlerde, hemodinamik monitörizasyon ve hastanın ihtiyacına göre sıvı tedavisinin yapılması önerilmektedir. Biz intraoperatif sıvı tedavilerini gözden geçirmeyi ve intraoperatif sıvı ilkelerine farkındalığı arttırmayı amaçladık.
Gereç ve Yöntemler:Genel anestezi uygulanan hastalar (393) çalışmaya dahil edildi. İntraoperatif sıvı uygulamaları, hastaların demografik özellikleri ve yapılmış olan operasyonun türüne göre verilmesi gereken sıvı miktarları ve türü belirlendi. Hastaların mevcut kayıtlarından verilmiş olan sıvı miktarlarına ait verilerle karşılaştırılma yapılarak sonuçlar analiz edildi.
Bulgular:Çalışmamızda hastalara verilen ortalama sıvı miktarı 2677,61 ml (11,3 ml/kg/saat) olarak bulunmuştur. IV vazopressör kullanılan hastalarda intraoperatif verilen ortalama sıvı miktarlarının kullanılmayan hastalara göre daha yüksek olduğu görüldü (3477,27 ml). ASA-3 grubu hastalar ASA1-2 grubu hastalarla kıyaslandığında, ASA-3 grubu hastalara intraoperatif dönemde verilen sıvı miktarı yüksekti (2795 ml). Cerrahi tipi ve intraoperatif verilen sıvı miktarları karşılaştırıldığında; yüksek riskli cerrahi grubunda intraoperatif verilen sıvı miktarının anlamlı olarak daha yüksek olduğunu gözlendi (3601,65 ml). Sıvı yönetiminde liberal uygulamalara yakın değerlerde olduğumuzu söyleyebiliriz. Kristaloid kullanımı klinik pratiğimizde en sık tercih ettiğimiz sıvı tipi olarak karşımıza çıkmaktadır.
Sonuç:Liberal ve restriktif sıvı rejimi kavramlarının değişkenliği, hedeflenen klinik ve fizyolojik parametrelerin standart olmaması nedeniyle kanıta dayalı kılavuz veya prosedüre özel bir sıvı tedavisi ortaya konamamıştır. Yüksek riskli hastalarda sıvı yönetimi için tek tip yaklaşım uygun olmayacaktır. Bizim çalışmamızda standart sıvı tedavisi uygulamaktayız, sonuçlarımız liberal sayılabilir. Hemodinamik monitorizasyon yöntemlerine ve hastanın sıvı gereksinimlerine dikkat edilerek replasman yapılmasının faydalı olacağını düşünmekteyiz.

Anahtar Sözcükler: Sıvı, Liberal, Restriktif, Perioperatif, Kristalloid, Kolloid

Kaynakça

  • 1.Yeager MP, Spence BC. Perioperative Fluid Management: Current consensus and controversies. Semin Dial 2006; 19: 472-9.
  • 2.Kaye AD, Riopelle JM. Intravasculer Fluid and Electrolyte Physiology. In: Miller RD. Miller’s Anesthesia (7th ed). Elsevier Churchill Livingstone: Philadelphia 2010; 1728-30.
  • 3.Holte K, Sharrock NE, Kehlet H. Pathophysiology and clinical implications of perioperative fluid excess. Br J Anaesth 2002; 89: 622-32.
  • 4.Chappel D, Jacob M, Hofmann-Kiefer K, Conzen P, Rehm M. A Rational Approach to Perioperative Fluid Management. Anesthesiology 2008; 109: 723-40.
  • 5.Nisanevich V, Felsenstein I, Almogy G, Weissman C, Einav S, Matot I. Effect of intraoperative fluid management on outcome after intraabdominal surgery. Anesthesiology 2005; 103: 25-32.
  • 6.Arkilic CF, Taguchi A, Sharma N, Ratnaraj J, Sessler DI, Read TE, Fleshman JW, Kurz A. Supplemental perioperative fluid administration increases tissue oxygen pressure. Surgery 2003; 133(1): 49-55.
  • 7.Kimberger O, Fleischmann E, Brandt S, Kugener A, Kabon B, Hiltebrand L, Krejci V, Kurz A. Supplemental oxygen, but not supplemental crystalloid fluid, increases tissue oxygen tension in healthy and anastomotic colon in pigs. Anesth Analg 2007; 105(3):773-9.
  • 8.Doherty M, Buggy D. Intraoperative fluids: how much is too much? J British Journal of Anaesthesia 2012; 109(1): 69-79.
  • 9.Gupta R, Gan TJ. Peri-operative fluid management to enhance recovery. Anaesthesia 2016; 71 Suppl 1: 40-5.
  • 10.Della Rocca G, Vetrugno L. Fluid therapy today: Where are we? Turk J Anaesth Reanim 2016; 44(5): 233-5.
  • 11.Rocca GD, Vetrugno L, Tripi G, Deana C, Barbariol F, Pompei L. Liberal or restricted fluid administration: are we ready for a proposal of a restricted intraoperative approach? Bio Medical Central Anesthesiology 2014; 14: 62.
  • 12.Nisanveich V, Feisenstein J, Almogy G, Weissman C, Einav S, Matot I. Effect of intraoperative fluid management on outcome after intraabdominal surgery. Anesthesiology 2005; 103: 25-32.
  • 13.De Aguilar-Nascimento JE, Diniz BN, do Carmo AV, Silveira EAO, Silva RM. Clinical benefits after the implementation of a protocol of restricted perioperative intravenous crystalloid fluids in major abdominal operations. World Journal of Surgery 2009; 33(5): 925-30.
  • 14.Warrillow SJ, Weinberg L, Parker F, Calzavacca P, Licari E. Perioperative fluid prescription, complications, and outcomes in major elective open gastrointestinal surgery. Anaesth Intensive Care 2010; 38: 251-65.
  • 15.Holte K, Kristensen BB, Valentiner L, Kehlet H. Liberal Versus Restrictive Fluid Management in Knee Arthroplasty: A Randomized, Double-Blind Study. Anesthesia and Analgesia 2007; 105(2): 465-74.
  • 16.Noblett SE, Snowden CP, Shenton BK, Horgan AF. Randomized clinical trial assessing the effect of Doppler-optimized fluid management on outcome after elective colorectal resection. Br J Surg 2006; 93(9): 1069–76.
  • 17.Kulemann B, Timme S, Seifert G,Holzner PA, Glatz T, Sick O, Chikhladze S, Bronsert B, Hoepner J, Werner M, Hopt VT, Marjanovic G. Intraoperative crystalloid overload leads to substantial inflammatory infiltration of intestinal anastomoses - a histomorphological analysis. Surgery 2013; 154(3): 596–603.
  • 18.Jacob M, Chappell D, Conzen P, Finsterer U, Rehm M. Blood volume is normal after pre-operative overnight fasting. Acta Anaesthesiol Scand 2008; 52: 522-9.
  • 19.Perel A. Iatrogenic hemodilution: a possible cause for avoidable blood transfusions? Critical Care 2017; 21(1): 291.
  • 20.Semler MW. Self WH, Wanderer JP, Ehrenfeld JM, Wang L, Bryn DW, Stollings JL, Kumar AB, Hughes CG, Hernandez A, Guillamondegui OD, May AK, Weavind L, Casey JD, Siew ED, Shaw AD, Rice TW. Balanced Crystalloids versus Saline in Critically Ill Adults. The New England Journal of Medicine 2018; 378: 829-39.
  • 21.Bundgaard-Nielsen M, Secher NH, Kehlet H. ‘Liberal’ vs. ‘restrictive’ perioperative fluid therapy - a critical assessment of the evidence. Acta Anaesthesiol Scand 2009; 53: 843-51.
  • 22.Brandstrup B, Tonnesen H, Beier-Holgersen R, Hjortso E, Ording H, Lindorff-Larsen K, Rasmussen RS, Lanng C, Wallin L, Iversen LH, Gramkow CS, Okholm M, Blemmer T, Svedsen PE, Rottensten HH, Thage B, Riis J, Jeppesen IS, Teilum D, Christensen AM, Graungoard B, Pott F. Effect of intravenous fluid restriction on postoperative complications: Comparison of to perioperative fluid regimens: A randomized assessor-blinded multicenter trial. Ann Surg 2003; 238: 641-8.
  • 23.MacKay G, Fearson K, McConnachie A, Serpell MG, Molloy RG, O’Dwyer PJ. Randomized clinical trial of the effect of postoperative intravenous fluid restriction on recovery after elective colorectal surgery. Br J Surg 2006; 93: 1469-74.
  • 24.Holte K, Foss NB, Anderson J, Valentiner L, Lund C, Bie P, Kehlet H. Liberal or restrictive fluid administration in fast-track colonic surgery: a randomized, double-blind study. Br J Anaesth 2007; 99(4): 500-8.
  • 25.Corcoran T, Rhodes JE, Clarke S, Myles PS, Ho KM. Perioperative fluid management strategies in major surgery: a stratified meta-analysis. Anesth Analg 2012; 114(3): 640 51.
  • 26.Cecconi M, Parsons AK, Rhodes A. What is a fluid challenge? Curr Opin Crit Care 2011; 17: 290-5.
  • 27.Miller TE, Roche AM, Mythen MMG. Fluid management and goal-directed therapy as an adjunct to Enhanced Recovery After Surgery (ERAS). Canadian Journal of Anaesthesia, Journal Canadien 2015; 62(2):158-68.

Evaluation of Intraoperative Fluid Management

Yıl 2022, Cilt: 8 Sayı: 1, 33 - 41, 01.01.2022
https://doi.org/10.53394/akd.1037455

Öz

ABSTRACT

Objective:Especially in large surgical procedures, it is recommended that the fluid treatment be performed according to the needs of the patient in the presence of hemodynamic monitoring during the operation. We aimed to review intraoperative fluid treatments and to increase awareness of intraoperative fluid management.
Methods:The patients (393) who underwent general anesthesia were included in the study. According to the information of intraoperative fluid applications, the demographic characteristics of the patients and the amount and type of fluid that should be given according to the type of operation performed were determined.
Results:In our study, the mean amount of fluid given to patients was found to be 2677.61 ml. The mean intraoperative fluid volume was higher in patients who were treated with IV vasopressors than in untreated patients (3477.27 ml). When compared with patients with ASA 1-2 group, the amount of fluid given to the patients in the ASA-3 group was high (2795 ml). Comparing the type of surgery and the amount of fluid given intraoperatively, we observed that the amount of intraoperative fluid was significantly higher in the high-risk surgical group (3601.65 ml). We can say that we are close to liberal practices as a liquid strategy. The use of balanced crystalloid with the closest content to plasma is the most preferred liquid type in our clinical practice.
Conclusion:Due to the variability of the concepts of liberal and restrictive fluid regimen and the lack of standardized targeted clinical and physiological parameters, no specific evidence-based guideline or procedure specific fluid treatment could be demonstrated. In our study, we see that fluid replacement is performed under standard fluid treatment, which still can be considered liberal. We think that it can be useful to use hemodynamic monitoring methods more frequently in patients who need them, also in selected patient groups.

Key Words: Fluid, Liberal, Restrictive, Perioperative, Crystalloid, Colloid

Kaynakça

  • 1.Yeager MP, Spence BC. Perioperative Fluid Management: Current consensus and controversies. Semin Dial 2006; 19: 472-9.
  • 2.Kaye AD, Riopelle JM. Intravasculer Fluid and Electrolyte Physiology. In: Miller RD. Miller’s Anesthesia (7th ed). Elsevier Churchill Livingstone: Philadelphia 2010; 1728-30.
  • 3.Holte K, Sharrock NE, Kehlet H. Pathophysiology and clinical implications of perioperative fluid excess. Br J Anaesth 2002; 89: 622-32.
  • 4.Chappel D, Jacob M, Hofmann-Kiefer K, Conzen P, Rehm M. A Rational Approach to Perioperative Fluid Management. Anesthesiology 2008; 109: 723-40.
  • 5.Nisanevich V, Felsenstein I, Almogy G, Weissman C, Einav S, Matot I. Effect of intraoperative fluid management on outcome after intraabdominal surgery. Anesthesiology 2005; 103: 25-32.
  • 6.Arkilic CF, Taguchi A, Sharma N, Ratnaraj J, Sessler DI, Read TE, Fleshman JW, Kurz A. Supplemental perioperative fluid administration increases tissue oxygen pressure. Surgery 2003; 133(1): 49-55.
  • 7.Kimberger O, Fleischmann E, Brandt S, Kugener A, Kabon B, Hiltebrand L, Krejci V, Kurz A. Supplemental oxygen, but not supplemental crystalloid fluid, increases tissue oxygen tension in healthy and anastomotic colon in pigs. Anesth Analg 2007; 105(3):773-9.
  • 8.Doherty M, Buggy D. Intraoperative fluids: how much is too much? J British Journal of Anaesthesia 2012; 109(1): 69-79.
  • 9.Gupta R, Gan TJ. Peri-operative fluid management to enhance recovery. Anaesthesia 2016; 71 Suppl 1: 40-5.
  • 10.Della Rocca G, Vetrugno L. Fluid therapy today: Where are we? Turk J Anaesth Reanim 2016; 44(5): 233-5.
  • 11.Rocca GD, Vetrugno L, Tripi G, Deana C, Barbariol F, Pompei L. Liberal or restricted fluid administration: are we ready for a proposal of a restricted intraoperative approach? Bio Medical Central Anesthesiology 2014; 14: 62.
  • 12.Nisanveich V, Feisenstein J, Almogy G, Weissman C, Einav S, Matot I. Effect of intraoperative fluid management on outcome after intraabdominal surgery. Anesthesiology 2005; 103: 25-32.
  • 13.De Aguilar-Nascimento JE, Diniz BN, do Carmo AV, Silveira EAO, Silva RM. Clinical benefits after the implementation of a protocol of restricted perioperative intravenous crystalloid fluids in major abdominal operations. World Journal of Surgery 2009; 33(5): 925-30.
  • 14.Warrillow SJ, Weinberg L, Parker F, Calzavacca P, Licari E. Perioperative fluid prescription, complications, and outcomes in major elective open gastrointestinal surgery. Anaesth Intensive Care 2010; 38: 251-65.
  • 15.Holte K, Kristensen BB, Valentiner L, Kehlet H. Liberal Versus Restrictive Fluid Management in Knee Arthroplasty: A Randomized, Double-Blind Study. Anesthesia and Analgesia 2007; 105(2): 465-74.
  • 16.Noblett SE, Snowden CP, Shenton BK, Horgan AF. Randomized clinical trial assessing the effect of Doppler-optimized fluid management on outcome after elective colorectal resection. Br J Surg 2006; 93(9): 1069–76.
  • 17.Kulemann B, Timme S, Seifert G,Holzner PA, Glatz T, Sick O, Chikhladze S, Bronsert B, Hoepner J, Werner M, Hopt VT, Marjanovic G. Intraoperative crystalloid overload leads to substantial inflammatory infiltration of intestinal anastomoses - a histomorphological analysis. Surgery 2013; 154(3): 596–603.
  • 18.Jacob M, Chappell D, Conzen P, Finsterer U, Rehm M. Blood volume is normal after pre-operative overnight fasting. Acta Anaesthesiol Scand 2008; 52: 522-9.
  • 19.Perel A. Iatrogenic hemodilution: a possible cause for avoidable blood transfusions? Critical Care 2017; 21(1): 291.
  • 20.Semler MW. Self WH, Wanderer JP, Ehrenfeld JM, Wang L, Bryn DW, Stollings JL, Kumar AB, Hughes CG, Hernandez A, Guillamondegui OD, May AK, Weavind L, Casey JD, Siew ED, Shaw AD, Rice TW. Balanced Crystalloids versus Saline in Critically Ill Adults. The New England Journal of Medicine 2018; 378: 829-39.
  • 21.Bundgaard-Nielsen M, Secher NH, Kehlet H. ‘Liberal’ vs. ‘restrictive’ perioperative fluid therapy - a critical assessment of the evidence. Acta Anaesthesiol Scand 2009; 53: 843-51.
  • 22.Brandstrup B, Tonnesen H, Beier-Holgersen R, Hjortso E, Ording H, Lindorff-Larsen K, Rasmussen RS, Lanng C, Wallin L, Iversen LH, Gramkow CS, Okholm M, Blemmer T, Svedsen PE, Rottensten HH, Thage B, Riis J, Jeppesen IS, Teilum D, Christensen AM, Graungoard B, Pott F. Effect of intravenous fluid restriction on postoperative complications: Comparison of to perioperative fluid regimens: A randomized assessor-blinded multicenter trial. Ann Surg 2003; 238: 641-8.
  • 23.MacKay G, Fearson K, McConnachie A, Serpell MG, Molloy RG, O’Dwyer PJ. Randomized clinical trial of the effect of postoperative intravenous fluid restriction on recovery after elective colorectal surgery. Br J Surg 2006; 93: 1469-74.
  • 24.Holte K, Foss NB, Anderson J, Valentiner L, Lund C, Bie P, Kehlet H. Liberal or restrictive fluid administration in fast-track colonic surgery: a randomized, double-blind study. Br J Anaesth 2007; 99(4): 500-8.
  • 25.Corcoran T, Rhodes JE, Clarke S, Myles PS, Ho KM. Perioperative fluid management strategies in major surgery: a stratified meta-analysis. Anesth Analg 2012; 114(3): 640 51.
  • 26.Cecconi M, Parsons AK, Rhodes A. What is a fluid challenge? Curr Opin Crit Care 2011; 17: 290-5.
  • 27.Miller TE, Roche AM, Mythen MMG. Fluid management and goal-directed therapy as an adjunct to Enhanced Recovery After Surgery (ERAS). Canadian Journal of Anaesthesia, Journal Canadien 2015; 62(2):158-68.
Toplam 27 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri
Bölüm Araştırma Makaleleri
Yazarlar

Hakan Temel Bu kişi benim 0000-0003-4135-2742

Bilge Karslı Bu kişi benim 0000-0003-4231-8300

Nurten Kayacan Bu kişi benim 0000-0003-3542-4375

Yesim Cetintas Bu kişi benim 0000-0002-1742-9204

Zekiye Bigat Bu kişi benim 0000-0002-2191-4595

Yayımlanma Tarihi 1 Ocak 2022
Gönderilme Tarihi 8 Şubat 2021
Yayımlandığı Sayı Yıl 2022 Cilt: 8 Sayı: 1

Kaynak Göster

APA Temel, H., Karslı, B., Kayacan, N., Cetintas, Y., vd. (2022). Evaluation of Intraoperative Fluid Management. Akdeniz Tıp Dergisi, 8(1), 33-41. https://doi.org/10.53394/akd.1037455