Doksisikline Bağlı Kardiyak Yan Etki Gelişen Bruselloz Olgusu

Yıl 2017, Cilt: 3 Sayı: 3, 219 - 221, 01.01.2017

Cihan Yeşil Yeşim Mecitoğlu Yağcı Özge Turhan Latife Mamıkoğlu

Öz

Tetrasiklinler birçok aerobik Gram pozitif ve Gram negatif bakteriye etkili geniş spektrumlu antibiyotiklerdir. Bu grupta yer alan doksisiklinin diğer antibiyotiklere benzer olarak birçok yan etkileri bulunmaktadır. Yazıda bruselloz tanılı hastamızın tedavi seyri sırasında doksisiklinin daha önce belirtilmeyen taşikardi ve ritim bozukluğu yan etkilerinin görüldüğü olgu sunulmuştur

Anahtar Kelimeler

Doksisiklin, Bruselloz, Yan etki

A Case of Brucellosis with Doxycycline-Related Cardiological Adverse Effects

Öz

The tetracyclines are considered to be broad-spectrum bacteriostatic antibiotics that are being used to treat infections caused by many aerobic gram-positive and gram–negative bacteria. There are some major adverse effects associated with doxycycline, which is considered a tetracycline. In this report, we submit a case where a patient with brucellosis developed tachycardia and arrhythmia, which were not previously known as adverse effects associated with doxycycline

Anahtar Kelimeler

Doxycycline, Brucellosis, Adverse effect

Kaynakça

• Klein NC, Cunha BA. Tetracyclines. Med Clin North Am 1995; 79:789-801.
• Schnappinger D, Hilen W. Tetracyclines: Antibiotic action, uptake, and resistance mechanisms Arch Microbiol 1996; 165:359-69.
• Moffa M, Brook I. Tetracyclines, Glycylcyclines, and Chloramphenicol. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. Diseases 8th ed. New York: Elsevier-Churchill Livingstone, 2015; 322-38.
• Smith K, Leyden JJ. Safety of doxycycline and minocycline: A systematic review. Clin Ther 2005; 27:1329-42.