Antalya Bölgesinde İnflamatuvar Bağırsak Hastalığının Epidemiyolojik ve Klinik Özellikleri

Yıl 2020, Cilt: 6 Sayı: 1, 32 - 41, 01.01.2020

Utku Iltar Haydar Adanır Mete Akın Dinç Dinçer

Öz

Amaç: Ülkemizde inflamatuvar bağırsak hastalığı İBH ile ilgili epidemiyolojik ve klinik veriler yetersizdir. Özellikle bölgemizle ilgili Batı Akdeniz yayınlanmış veriye rastlanmamıştır. Çalışmanın amacı Antalya bölgesinde İBH tanılı hastaların klinik, epidemiyolojik ve demografik özelliklerinin değerlendirilmesidir.Gereç ve Yöntemler: İBH tanılı toplam 136 hasta retrospektif olarak değerlendirildi. Her hasta için hasta dosyaları, hastane verileri kullanılarak tamamlanan anketler oluşturuldu.Bulgular: Çalışma sürecinde 100 ülseratif kolit ÜK %73,5 ve 36 Crohn hastalığı CH %26,5 tespit edildi. Hastaların tanı yaşları CH için 20-30 yaşlar arasında ve 50-60 yaşları arasında olmak üzere 2 pikli karakteristik dağılım gösterdi. Kadın erkek oranı CH için 1 ve ÜK için 1,4 idi. İBH nedeniyle ameliyat olan hasta sayısı CH için 14 %38,8 olup daha sıktı. Şikâyet başlangıcı ile tanı arasında geçen ortalama medyan süre CH için 12 ay ve ÜK için 2 ay olarak saptandı. Komplikasyonlar açısından değerlendirildiğinde, en sık gözlenen bağırsak dışı komplikasyon hem CH hem de ÜK için akut artropatiydi. Sonuç: Çalışma sonuçlarının büyük bölümü daha önceki çalışma sonuçları ve literatür verileri ile uyumluydu. ÜK ve CH için hasta oranları bölgesel farklılıklar gösterdi. ÜK özellikle Doğu Anadolu kökenli hastalarda anlamlı yüksekti. Kadın/erkek oranı ÜK’de daha yüksekti. Yanlış tanı oranı CH için daha yüksekti. Semptom başlangıcı ile tanı arası geçen süre CH için belirgin yüksekti

Anahtar Kelimeler

İnflamatuvar bağırsak hastalığı, Ülseratif kolit, Crohn hastalığı

Epidemiological and Clinical Characteristics of Inflammatory Bowel Disease in the Antalya Region

Öz

Objective: Epidemiological and clinical data on inflammatory bowel disease IBD are insufficient in our country. There are no published data, especially from the Western Mediterranean Region. The purpose of this study was the evaluation of the clinical, epidemiological and demographical characteristics of patients with IBD in the Antalya region.Material and Methods: A total of 136 patients with a diagnosis of IBD were evaluated retrospectively. Questionnaires were completed for each patient using data from the patient files and hospital records.Results: During the study period, 100 ulcerative colitis UC 75.5% and 36 Crohn's disease CD 26.5% patients were identified. The age of the patients with CD showed the characteristic biphasic distribution with 2 peaks between 20 and 30 and then 50 and 60 years. The female/male ratio was 1/1 in CD and 1.4/1 in UC. Surgical interventions due to disease were more common in CD 38.8% . The mean lag time between the onset of complaints and confirmation of diagnosis was 12 and 2 months for CD and UC, respectively. As for complications, the most common extra intestinal complication was found to be acute arthropathy. Conclusion: The majority of our results were consistent with previous study results and literature data. The rates of patients with UC and CD showed regional differences. UC was significantly higher in patients with an Eastern Anatolia origin. The female/male ratio was higher in UC. There was a higher prevalence of misdiagnosis for CD. The mean time between the onset of symptoms and the time of diagnosis was significantly higher for CD

Anahtar Kelimeler

Inflammatory bowel disease, Ulcerative colitis, Crohnʼs disease

Kaynakça

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