WHICH TREATMENT SHOULD BE SELECTED FOR THE OPTIMUM APPROACH TO PATIENTS WITH NON-SMALL CELL LUNG CANCER WITH DRIVER MUTATION? A CASE REPORT AND LITERATURE REVIEW

Onur Yazdan Balçık; Esin Oktay; Gizem Dönmez Yalçın

doi:10.53394/akd.996247

Olgu Sunumu

Birden Fazla Sürücü Mutasyonlu Küçük Hücre Olmayan Akciğer Kanserli Hastalarda Optimum Yaklaşım İçin Hangi Tedavi Seçilmelidir? Bir Vaka Raporu ve Literatür İncelemesi

Yıl 2023, Cilt: 9 Sayı: 2, 226 - 230, 01.05.2023

Onur Yazdan Balçık Esin Oktay Gizem Dönmez Yalçın

https://doi.org/10.53394/akd.996247

Öz

59 yaşındaki bir hastada küçük hücreli olmayan akciğer kanserinde (KHDAK) bir anaplastik lenfoma kinaz (ALK) ve c-ros onkogen 1 (ROS1) füzyonu vakasını sunuyoruz ve ko-mutasyonların tedavi etkinliğini gözden geçiriyoruz. Tedavinin seçimi ve nadir ko-mutasyonlarla etkinliği oldukça ilgi çeken bir konudur. Bu derleme, birden fazla sürücü mutasyonu olan KHDAK hastalarına optimal tedavi yaklaşımına dair ipuçları sağlayacaktır. Bununla birlikte, hangi hastaların uygun TKI veya kemoterapiden fayda görebileceğini netleştirmek için randomize çalışmalara ihtiyaç vardır.
Anahtar Kelimeler: Akciğer, Mutasyon, Alk, Ros

Anahtar Kelimeler

ALK, ROS, MUTASYON, AKCİĞER

Kaynakça

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