Klinik Araştırma
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Predictive Factors and Long Term Outcomes of Urethroplasty In Male Anterior Urethral Stricture: Single Center Study

Yıl 2025, Cilt: 11 Sayı: 3, 382 - 387, 29.09.2025
https://doi.org/10.53394/akd.1531575

Öz

Objective: The present study aimed to evaluate predictive factors affecting success rates and long term outcomes of urethroplasty due to male anterior urethral stricture.
Material and Methods: Thirty-five patients who underwent anastomotic (EAT) urethroplasty and eighteen patients who underwent buccal mucosa graft (BMG) urethroplasty were evaluated retrospectively. Age, endoscopic interventions before urethroplasty, stricture length, follow-up time and re-stricture time were compared between groups. Univariate and Cox’s multivariate analyses were calculated to determine predictive factors of success. Kaplan Meier analysis was plotted to identify the stricture free survival.
Results: Both EAT and BMG techniques have similar success rate (65.7% and 72.2%, p:0.634) and mean re-stricture time (4.18 and 3.4 months, p: 0.556) respectively. The stricture length was shown to be the prominent predictive factor for success (HR 1.6; 95% CI 0.453–12.797; p < 0.001).
Conclusions: Both urethroplasty techniques had similar success rates. The length of stricture is the most reliable factor affecting success of surgery.

Kaynakça

  • 1. Santucci RA, Joyce GF, Wise M. Male Urethral Stricture Disease. Journal of Urology 2007; 177(5):1667–74.
  • 2. Wessells H, Angermeier KW, Elliott S, Gonzalez CM, Kodama R, Peterson AC. Male Urethral Stricture: American Urological Association Guideline. Journal of Urology 2017; 197(1):182–90.
  • 3. Horiguchi A. Substitution urethroplasty using oral mucosa graft for male anterior urethral stricture disease: Current topics and reviews. Int J Urol 2017; 24(7):493-503.
  • 4. Barbagli G, Montorsi F, Balò S, Sansalone S, Loreto C, Butnaru D, Bini V, Lazzeri M. Treatments of 1242 bulbar urethral strictures: multivariable statistical analysis of results. World J Urol 2019; 37(6):1165-71.
  • 5. Kulkarni S, Barbagli G, Sansalone S, Lazzeri M. One‐sided anterior urethroplasty: a new dorsal onlay graft technique. Wiley Online Library 2009; 104(8):1150–5.
  • 6. Eltahawy EA, Virasoro R, Schlossberg SM, McCammon KA, Jordan GH. Long-Term Followup for Excision and Primary Anastomosis for Anterior Urethral Strictures. Journal of Urology 2007; 177(5):1803–6.
  • 7. Waxman SW, Morey AF. Management of urethral strictures. Lancet. 2006; 367(9520):1379-80.
  • 8. Redón-Gálvez L, Molina-Escudero R, Álvarez-Ardura M, Otaola-Arca H, Alarcón Parra RO, Páez-Borda Á. Predictors of urethral stricture recurrence after endoscopic urethrotomy. Actas Urol Esp 2016; 40(8):529-33.
  • 9. Meneghini A , Cacciola A, Cavarretta L, Abatangelo G, Ferrarrese P, Tasca A. Bulbar urethral stricture repair with buccal mucosa graft urethroplasty. Eur Urol 2001; 39(3):264-7.
  • 10. Suh JG, Choi WS, Paick JS, Kim SW. Surgical Outcome of Excision and End-to-End Anastomosis for Bulbar Urethral Stricture. Korean J Urol 2013; 54(7):442-7.
  • 11. Verla W, Waterloos M, Spinoit AF, Buelens S, De Bleser E, Oosterlinck W, Martins F, Palminteri E, Ploumidis A, Lumen N. Primary versus Redo Urethroplasty: Results from a Single-Center Comparative Analysis. Biomed Res Int 2020; 2020:7214718.
  • 12. Mundy AR. Pelvic fracture injuries of the posterior urethra. World J Urol 1999; 17(2):90–5.
  • 13. Yalçınkaya F, Kartal I. Critical analysis of urethroplasty for male anterior urethral stricture: a single-center experience. World J Urol 2020; 38(9):2313-9.
  • 14. Kessler TM, Schreiter F, Kralidis G, Heitz M, Olianas R, Fisch M. Long-term results of surgery for urethral stricture: a statistical analysis. J Urol 2003; 170(3):840-4.

Erkek Hastalardaki Ön Üretral Darlıklarda Uygulanan Üretroplastinin Başarısını Etkileyen Faktörlerin ve Uzun Dönem Sonuçların Değerlendirilmesi: Tek Merkezli Çalışma

Yıl 2025, Cilt: 11 Sayı: 3, 382 - 387, 29.09.2025
https://doi.org/10.53394/akd.1531575

Öz

Amaç: Çalışma, erkek anterior üretral darlıklarda uygulanan üretroplastinin başarı oranını saptamayı ve başarıyı etkileyen faktörleri tespit etmeyi amaçlamaktadır.
Gereç ve Yöntemler: Primer anostomoz (PA) ve bukkal mukoza grefti (BMG) teknikleri ile üretroplasti yapılan 35 ve 18 hastanın verileri geriye yönelik incelendi. Yaş, üretroplasti öncesi cerrahi girişimler, takip süresi ve rekürrens süresi ile gruplar değerlendirildi. Tek yönlü ve çok yönlü Cox’s analizleri ile başarıyı etkileyen faktörler araştırıldı. Rekürrenssiz sağ kalım süresi Kaplan Meier analizi ile tespit edildi.
Bulgular: Her iki cerrahi tekniğin de (PA ve BMG) benzer başarı oranları (%65.7 ve %72.2, p:0.634) ve ortalama rekürrens sürelerine (4.18 ve 3.4 ay, p: 0.556) sahip olduğu tespit edildi. Darlık uzunluğunun başarıyı etkileyen en belirgin faktör olduğu görüldü (HR 1.6; 95% CI 0.453–12.797; p < 0.001).
Sonuç: Çalışmamız, PA ve BMG tekniklerinin benzer başarı oranlarına sahip olduğunu ve üretroplasti başarısını etkileyen en belirgin faktörün darlık uzunluğu olduğunu ortaya koymaktadır.

Destekleyen Kurum

None

Kaynakça

  • 1. Santucci RA, Joyce GF, Wise M. Male Urethral Stricture Disease. Journal of Urology 2007; 177(5):1667–74.
  • 2. Wessells H, Angermeier KW, Elliott S, Gonzalez CM, Kodama R, Peterson AC. Male Urethral Stricture: American Urological Association Guideline. Journal of Urology 2017; 197(1):182–90.
  • 3. Horiguchi A. Substitution urethroplasty using oral mucosa graft for male anterior urethral stricture disease: Current topics and reviews. Int J Urol 2017; 24(7):493-503.
  • 4. Barbagli G, Montorsi F, Balò S, Sansalone S, Loreto C, Butnaru D, Bini V, Lazzeri M. Treatments of 1242 bulbar urethral strictures: multivariable statistical analysis of results. World J Urol 2019; 37(6):1165-71.
  • 5. Kulkarni S, Barbagli G, Sansalone S, Lazzeri M. One‐sided anterior urethroplasty: a new dorsal onlay graft technique. Wiley Online Library 2009; 104(8):1150–5.
  • 6. Eltahawy EA, Virasoro R, Schlossberg SM, McCammon KA, Jordan GH. Long-Term Followup for Excision and Primary Anastomosis for Anterior Urethral Strictures. Journal of Urology 2007; 177(5):1803–6.
  • 7. Waxman SW, Morey AF. Management of urethral strictures. Lancet. 2006; 367(9520):1379-80.
  • 8. Redón-Gálvez L, Molina-Escudero R, Álvarez-Ardura M, Otaola-Arca H, Alarcón Parra RO, Páez-Borda Á. Predictors of urethral stricture recurrence after endoscopic urethrotomy. Actas Urol Esp 2016; 40(8):529-33.
  • 9. Meneghini A , Cacciola A, Cavarretta L, Abatangelo G, Ferrarrese P, Tasca A. Bulbar urethral stricture repair with buccal mucosa graft urethroplasty. Eur Urol 2001; 39(3):264-7.
  • 10. Suh JG, Choi WS, Paick JS, Kim SW. Surgical Outcome of Excision and End-to-End Anastomosis for Bulbar Urethral Stricture. Korean J Urol 2013; 54(7):442-7.
  • 11. Verla W, Waterloos M, Spinoit AF, Buelens S, De Bleser E, Oosterlinck W, Martins F, Palminteri E, Ploumidis A, Lumen N. Primary versus Redo Urethroplasty: Results from a Single-Center Comparative Analysis. Biomed Res Int 2020; 2020:7214718.
  • 12. Mundy AR. Pelvic fracture injuries of the posterior urethra. World J Urol 1999; 17(2):90–5.
  • 13. Yalçınkaya F, Kartal I. Critical analysis of urethroplasty for male anterior urethral stricture: a single-center experience. World J Urol 2020; 38(9):2313-9.
  • 14. Kessler TM, Schreiter F, Kralidis G, Heitz M, Olianas R, Fisch M. Long-term results of surgery for urethral stricture: a statistical analysis. J Urol 2003; 170(3):840-4.
Toplam 14 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Üroloji
Bölüm Araştırma Makalesi
Yazarlar

Ahmet Ender Caylan 0000-0003-1053-915X

Oğuzhan Önal 0009-0007-2923-7828

Erken Görünüm Tarihi 22 Eylül 2025
Yayımlanma Tarihi 29 Eylül 2025
Gönderilme Tarihi 11 Ağustos 2024
Kabul Tarihi 4 Eylül 2024
Yayımlandığı Sayı Yıl 2025 Cilt: 11 Sayı: 3

Kaynak Göster

Vancouver Caylan AE, Önal O. Predictive Factors and Long Term Outcomes of Urethroplasty In Male Anterior Urethral Stricture: Single Center Study. Akd Tıp D. 2025;11(3):382-7.