Gastrointestinal sistem lenfoproliferatif lezyonlara pratik yaklaşım

Yıl 2022, Cilt: 31 Sayı: 3, 213 - 230, 30.09.2022

Tuğba Toyran

https://doi.org/10.17827/aktd.1140953

Öz

Gastrointestinal sistem, reaktif lenfoid hiperplaziden lenfomaya kadar uzanan lenfoproliferatif lezyonların primer lokalizasyon bölgesidir. Bu hastalıkların teşhisi, özellikle küçük endoskopik biyopsilerde zordur ve doğru tanıya ulaşabilmek için klinik, morfolojik, immünohistokimyasal ve moleküler verilere dayalı entegre bir yaklaşıma ihtiyaç duyulmaktadır. Bu derlemede, gastrointestinal sistemde izlenen Hodgkin dışı lenfomaların temel histolojik özellikleri ile birlikte ayırıcı tanıya giren antiteler tartışılmıştır.

Anahtar Kelimeler

Gastrointestinal sistem, Hodgkin dışı lenfomalar, B hücreli lenfoma, T hücreli lenfoma, ekstranodal lenfoma

Teşekkür

Derleme yazım süresince, desteğini her zaman hissettiğim, yardım ve katkılarıyla beni yönlendiren, benimle tecrübelerini ve vakalarını paylaşan değerli hocam Prof.Dr.Melek Ergin’e çok teşekkür ederim.

Practical approach to gastrointestinal system lymphoproliferative lesions

Öz

The gastrointestinal tract is the primary localization site of lymphoproliferative lesions ranging from reactive lymphoid hyperplasia to lymphoma. Diagnosis of these diseases is difficult, especially in small endoscopic biopsies. And integrated approach based on clinical, morphological, immunohistochemical and molecular data is needed for accurate diagnosis. In this review, the basic histological features of non-Hodgkin lymphomas in the gastrointestinal tract and the entities included in the differential diagnosis are discussed.

Anahtar Kelimeler

Gastrointestinal tract, non-Hodgkin's lymhoma, B-cell lymphoma, T-cell lymphoma, extranodal lymphoma

Kaynakça

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