Chemical Components and Antibacterial Activity of Asphalt Grass (Bituminaria bituminosa (L.) C.H.Stirt) Growing in Tekirdag Province

Yıl 2024, , 773 - 781, 20.08.2024

Hilmican Çalışkan , Muazzez Gürgan Eser

https://doi.org/10.35414/akufemubid.1417456

Öz

The aim of this study was to investigate the chemical constituents of Bituminaria bituminosa (L.) C.H.Stirt growing in Tekirdag province by GC-MS method and to determine the antibacterial activity of crude extracts. The chemical constituents of hexane, dichloromethane and methanol extracts obtained from B. bituminosa plant by Soxhlet method were investigated using GC-MS method. As a result of our research on the chemical components of B. bituminosa, thirty-four compounds were detected in hexane extract, thirty-eight compounds in dichloromethane extract and thirty-five compounds in methanol extract. The highest antibacterial effect on both Gram-positive and Gram-negative bacteria tested in the study was obtained in the hexane extract of B. bituminosa.

Anahtar Kelimeler

Bituminaria, B. bituminosa, Chemical Components, GC-MS Analysis, Antibacterial Activity

Tekirdağ İlinde Yetişen Asfalt Otu (Bituminaria bituminosa (L.) C.H.Stirt) Bitkisinin Kimyasal Bileşenleri ve Antibakteriyel Aktivitesi

Öz

Bu çalışmadaki amacımız, Tekirdağ ilinde yetişen Bituminaria bituminosa (L.) C.H.Stirt bitkisinin kimyasal bileşenlerini GC-MS yöntemi ile araştırmak ve ham ekstrelerinde antibakteriyel aktivitesini belirlemektir. B. bituminosa bitkisinden Soxhlet metodu ile elde edilen hekzan, diklorometan ve metanol ekstresinin kimyasal bileşenleri, GC-MS yöntemi kullanılarak araştırılmıştır. B. bituminosa'nın kimyasal bileşenleri üzerine yaptığımız araştırma sonucunda hekzan ekstresinde otuz dört adet, diklorometan ekstresinde otuz sekiz adet ve metanol ekstresinde otuz beş adet bileşik tespit edilmiştir. Çalışmada denenen hem Gram-pozitif hem de Gram-negatif bakteriler üzerinde en yüksek antibakteriyel etki B. bituminosa'nın hekzan ekstresinde elde edilmiştir.

Anahtar Kelimeler

Bituminaria, B. bituminosa, Kimyasal Bileşen, GC-MS Analizi, Antibakteriyel Aktivite

Kaynakça

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