Koloidal Tek Tabaka Transferine Dayalı Metalik Nano Şablonların Biyosensör Yüzeyler Olarak Hazırlanması

Yıl 2020, , 319 - 330, 20.05.2020

Numan Gözübenli

https://doi.org/10.35414/akufemubid.604735

Öz

Kat-kat (LbL) transfer tekniği, nanoyapılı malzemelerin hazırlanmasında yaygın olarak kullanılan basit, çok yönlü bir yaklaşım olarak dikkat çekmektedir. Bu süreç, polimerler, nanopartiküller, lipitler, proteinler veya organik boya molekülleri gibi bileşenlerin sırayla biriktirilmesi işlemine dayalı olup, bunların üç boyutlu kristal dizilimlerinden, serbest duran (iki boyutlu) şablonlar elde etmede kullanılan katmanların tek tek uzaklaştırılması sürecidir. Her ne kadar malzeme özelliklerinin (örn. boyut, bileşim, kalınlık, geçirgenlik, işlev, vb.) LbL transferinde hazırlanan malzemenin kendisi tarafından sağlanmasına rağmen, şablonların morfolojisi ve bileşimi de üretilen malzemelerin özelliklerinin ve dolayısıyla potansiyel uygulamaların belirlenmesinde önemli bir rol oynar. Bu çalışmada, çok çeşitli yüzeylerde tek katmanlı, fonksiyonel silika koloidal kristallerin ölçeklenebilir bir şekilde imal edilmesini sağlayan basit bir koloidal transfer teknolojisi rapor edilmiştir. Olağandışı bir yapıya sahip iki boyutlu koloidal kristal dizilimlerin ilk önce cam bir yüzey üzerine bir döner (spin)-kaplama tekniği ile kaplanması sağlanır. Koloidal kristal tabakalar üzerine dökülen bir poliüretan (PÜ) filmi, üzerleri açık partikül dizilerini çeşitli yüzeylere aktarabilmek için kullanılmaktadır. Transfer edilen tek tabakalı koloidal kristalin birim aralığı, PÜ-silika kompozit filminin çeşitli süreler boyunca metalik kaplama ile veya termal olarak işlenmesiyle kolayca ayarlanabilir. Bu çalışmada; yapısal şablon olarak transfer edilen tek tabakalı temassız koloidal kristallerin, altın kaplanmış nano kürecikler olarak periyodik dizili sensör yüzeyler olarak geliştirilebileceği kanıtlandı. Elde edilen plazmonik dizinin, optiksel biyo algılayıcılarda sıkça kullanılmakta olan benzentiyol molekülleri için yüksek seçicilikte Raman saçılma piklerine sahip olduğu gösterilmiştir.

Anahtar Kelimeler

Döner (spin) kaplama, Koloidal silika kristali, Fotonik kristal, Nanoküreler, Nanokabuklar

Destekleyen Kurum

HARRAN ÜNİVERSİTESİ

Proje Numarası

18206

Teşekkür

Bu proje, Harran Üniversitesi, BAP tarafından, Biyomoleküllerin saflaştırılmasında kullanılacak manyetik nano partiküllerin üretimi başlıklı, 18206 nolu proje ile desteklenmiştir. Ayrıca makalede destek veren Harran Üniversitesi Bölüm Mensuplarına teşekkür ederim.

Preparation of Metalic Nano-Templates Based on Transfer of Colloidal Monolayer as Biosensor Surfaces

Öz

Layer-by-layer (LbL) transfer technique stands out as a simple, versatile approach commonly used in the preparation of nanostructured materials. This process is based on the sequential deposition of components such as polymers, nanoparticles, lipids, proteins, or organic dye molecules, and the process of removing individual layers from their three-dimensional crystal arrays to obtain free-standing templates. Although the material properties (eg size, composition, thickness, permeability, function, etc.) are provided by the material itself prepared in the LbL transfer, the morphology and composition of the templates also play an important role in determining the properties of the materials produced and hence in the potential applications. In this study, a simple colloidal transfer technology, which enables the scalable production of monolayer functional silica colloidal crystals on a wide variety of surfaces, is reported. The two-dimensional colloidal crystal arrays having an unusual structure are first coated onto a glass surface by a spin-coating technique. A polyurethane (PU) film cast over the colloidal crystal layer is used to transfer uncoated particle arrays into various surfaces. The unit spacing of the transferred monolayer colloidal crystal can be easily adjusted by thermal process or with metallic coating of the PU-silica composite film for various periods of time. In this study; it has been proved that monolayer non-close colloidal crystals transferred as structural templates can be developed as highly ordered array sensor surfaces containing gold-coated nanospheres. The resulting plasmonic array has been shown to have high selectivity Raman scattering peaks for benzenthiol molecules commonly used in optical biosensors.

Anahtar Kelimeler

Spin coating, Colloidal silica crystal, Photonic crystal, Nanospheres, Nanoshells

Proje Numarası

18206

Kaynakça

• AGARWAL, S.; RAY, B.; MEHROTRA, R. SERS as an advanced tool for investigating chloroethyl nitrosourea derivatives complexation with DNA. International Journal of Biological Macromolecules, v. 81, p. 891-897, 11// 2015. ISSN 0141-8130. Disponível em: < http://www.sciencedirect.com/science/article/pii/S014181301500639X >.
• AMIRI, A. et al. Microwave-assisted direct coupling of graphene nanoplatelets with poly ethylene glycol and 4-phenylazophenol molecules for preparing stable-colloidal system. Colloids and Surfaces a-Physicochemical and Engineering Aspects, v. 487, p. 131-141, Dec 20 2015. ISSN 0927-7757. Disponível em: < <Go to ISI>://WOS:000365360000016 >.
• ASKAR, K. et al. Self-assembled self-cleaning broadband anti-reflection coatings. Colloids and Surfaces a-Physicochemical and Engineering Aspects, v. 439, p. 84-100, Dec 2013. ISSN 0927-7757. Disponível em: < <Go to ISI>://WOS:000327828700007 >.
• BARDOSOVA, M. et al. The Langmuir-Blodgett Approach to Making Colloidal Photonic Crystals from Silica Spheres. Advanced Materials, v. 22, n. 29, p. 3104-3124, 2010. ISSN 1521-4095. Disponível em: < http://dx.doi.org/10.1002/adma.200903708 >.
• BARTLETT, A. P. et al. Modified Spin-coating Technique to Achieve Directional Colloidal Crystallization. Langmuir, v. 28, n. 6, p. 3067-3070, Feb 14 2012. ISSN 0743-7463. Disponível em: < <Go to ISI>://WOS:000300138500002 >.
• BOWDEN, N. et al. Mesoscale self-assembly of hexagonal plates using lateral capillary forces: Synthesis using the "capillary bond". Journal of the American Chemical Society, v. 121, n. 23, p. 5373-5391, Jun 1999. ISSN 0002-7863. Disponível em: < <Go to ISI>://000081006000004 >.
• BREAULT-TURCOT, J.; MASSON, J.-F. Nanostructured substrates for portable and miniature SPR biosensors. Analytical and Bioanalytical Chemistry, v. 403, n. 6, p. 1477-1484, Jun 2012. ISSN 1618-2642. Disponível em: < <Go to ISI>://WOS:000304166500003 >.
• BURRS, S. L. et al. A comparative study of graphene-hydrogel hybrid bionanocomposites for biosensing. Analyst, v. 140, n. 5, p. 1466-1476, 2015. ISSN 0003-2654. Disponível em: < http://dx.doi.org/10.1039/C4AN01788A >.
• CABRERA, E. J. et al. Photonic Characteristics of Langmuir-Blodgett Self-Assembled Monolayers of Colloidal Silica Particles. Nanoscience and Nanotechnology Letters, v. 5, n. 1, p. 41-45, Jan 2013. ISSN 1941-4900. Disponível em: < <Go to ISI>://WOS:000317250200007 >.
• CHOI, D. G. et al. Colloidal lithographic nanopatterning via reactive ion etching. Journal of the American Chemical Society, v. 126, n. 22, p. 7019-7025, Jun 9 2004. ISSN 0002-7863. Disponível em: < <Go to ISI>://WOS:000221828200041 >.
• CHUNG, J. W.; BERNHARDT, R.; PYUN, J. C. Sequential analysis of multiple analytes using a surface plasmon resonance (SPR) biosensor. Journal of Immunological Methods, v. 311, n. 1-2, p. 178-188, Apr 20 2006. ISSN 0022-1759. Disponível em: < <Go to ISI>://WOS:000237527200018 >.
• DAHOUMANE, S. A. et al. Stoichiometrically controlled production of bimetallic Gold-Silver alloy colloids using micro-alga cultures. Journal of Colloid and Interface Science, v. 416, p. 67-72, Feb 15 2014. ISSN 0021-9797. Disponível em: < <Go to ISI>://WOS:000330162200010 >.
• FENOLLOSA, R.; MESEGUER, F. Non-close-packed artificial opals. Advanced Materials, v. 15, n. 15, p. 1282-+, Aug 5 2003. ISSN 0935-9648. Disponível em: < <Go to ISI>://WOS:000184798700011 >.
• GOZUBENLI, N.; YASUN, E.; BOSKIC, L. Fabrication of nanoporous film by transfer of colloidal particles and application to biomacromolecules. Applied Nanoscience, v. 8, n. 4, p. 739-750, 2018/04/01 2018. ISSN 2190-5517. Disponível em: < https://doi.org/10.1007/s13204-018-0825-6 >.
• GRZYBOWSKI, B. A.; STONE, H. A.; WHITESIDES, G. M. Dynamic self-assembly of magnetized, millimetre-sized objects rotating at a liquid-air interface. Nature, v. 405, n. 6790, p. 1033-1036, Jun 2000. ISSN 0028-0836. Disponível em: < <Go to ISI>://000087871700039 >.
• HOLTZ, J. H.; ASHER, S. A. Polymerized colloidal crystal hydrogel films as intelligent chemical sensing materials. Nature, v. 389, n. 6653, p. 829-832, 1997/10/01 1997. ISSN 1476-4687. Disponível em: < https://doi.org/10.1038/39834 >.
• HOMOLA, J. Surface plasmon resonance (SPR) biosensors and their applications in food safety and security. Frontiers in Planar Lightwave Circuit Technology Design, Simulation, and Fabrication, v. 216, p. 101-118, 2006 2006. Disponível em: < <Go to ISI>://WOS:000235996200004 >.
• HOU, Y. H. et al. Isolation of PCR-ready genomic DNA from Aspergillus niger cells with Fe3O4/SiO2 microspheres. Separation and Purification Technology, v. 116, p. 101-106, Sep 2013. ISSN 1383-5866. Disponível em: < <Go to ISI>://WOS:000323355800013 >.
• HUR, J.; WON, Y.-Y. Fabrication of high-quality non-close-packed 2D colloid crystals by template-guided Langmuir-Blodgett particle deposition. Soft Matter, v. 4, n. 6, p. 1261-1269, 2008 2008. ISSN 1744-683X. Disponível em: < <Go to ISI>://WOS:000255927700021 >.
• IMURA, Y. et al. Characterization of colloidal crystal film of polystyrene particles at the air-suspension interface. Journal of Colloid and Interface Science, v. 336, n. 2, p. 607-611, 2009. ISSN 0021-9797. Disponível em: < http://www.sciencedirect.com/science/article/pii/S0021979709004469 >.
• JAIN, S.; CWANG, C.; ADEYEYE, A. O. Magnetoresistance behavior of ferromagnetic nanorings in a ring-wire hybrid configuration. Nanotechnology, v. 19, n. 8, Feb 2008. ISSN 0957-4484. Disponível em: < <Go to ISI>://WOS:000252967400005 >.
• JANG, S. G. et al. Nanoscopic Ordered Voids and Metal Caps by Controlled Trapping of Colloidal Particles at Polymeric Film Surfaces. Advanced Materials, v. 20, n. 24, p. 4862-+, Dec 17 2008. ISSN 0935-9648. Disponível em: < <Go to ISI>://WOS:000262292200042 >.
• JIANG, H.; YU, K.; WANG, Y. Antireflective structures via spin casting of polymer latex. Optics Letters, v. 32, n. 5, p. 575-577, 2007/03/01 2007. Disponível em: < http://ol.osa.org/abstract.cfm?URI=ol-32-5-575 >.
• JIANG, P. Large-Scale Fabrication of Periodic Nanostructured Materials by Using Hexagonal Non-Close-Packed Colloidal Crystals as Templates. Langmuir, v. 22, n. 9, p. 3955-3958, 2013/12/25 2006. ISSN 0743-7463. Disponível em: < http://dx.doi.org/10.1021/la052326x >.
• JIANG, P. et al. Single-crystal colloidal multilayers of controlled thickness. Chemistry of Materials, v. 11, n. 8, p. 2132-2140, Aug 1999. ISSN 0897-4756. Disponível em: < <Go to ISI>://WOS:000082108800029 >.
• JIANG, P.; MCFARLAND, M. J. Large-Scale Fabrication of Wafer-Size Colloidal Crystals, Macroporous Polymers and Nanocomposites by Spin-Coating. Journal of the American Chemical Society, v. 126, n. 42, p. 13778-13786, 2013/12/25 2004. ISSN 0002-7863. Disponível em: < http://dx.doi.org/10.1021/ja0470923 >.
• KIM, J. J. et al. Fabrication of Size-Controllable Hexagonal Non-Close-Packed Colloidal Crystals and Binary Colloidal Crystals by Pyrolysis Combined with Plasma−Electron Coirradiation of Polystyrene Colloidal Monolayer. Langmuir, v. 27, n. 6, p. 2334-2339, 2011/03/15 2011. ISSN 0743-7463. Disponível em: < http://dx.doi.org/10.1021/la104881w >. Acesso em: 2013/07/31.
• KIM, S.-H. et al. Biofunctional colloids and their assemblies. Soft Matter, v. 6, n. 6, p. 1092-1110, 2010 2010. ISSN 1744-683X. Disponível em: < <Go to ISI>://WOS:000277833400003 >.
• LEE, C. K. et al. Characterizing the localized surface plasmon resonance behaviors of Au nanorings and tracking their diffusion in bio-tissue with optical coherence tomography. Biomedical Optics Express, v. 1, n. 4, p. 1060-1074, Nov 2010. ISSN 2156-7085. Disponível em: < <Go to ISI>://WOS:000208209300002 >.
• LI, N.; SCHWARTZ, M.; IONESCU-ZANETTI, C. PDMS Compound Adsorption in Context. Journal of Biomolecular Screening, v. 14, n. 2, p. 194-202, Feb 2009. ISSN 1087-0571. Disponível em: < <Go to ISI>://WOS:000263990000009 >.
• LI, X. et al. Modulating Two-Dimensional Non-Close-Packed Colloidal Crystal Arrays by Deformable Soft Lithography. Langmuir, v. 26, n. 4, p. 2930-2936, Feb 16 2010. ISSN 0743-7463. Disponível em: < <Go to ISI>://WOS:000274342200108 >.
• LIU, X. et al. Periodic arrays of metal nanorings and nanocrescents fabricated by a scalable colloidal templating approach. Journal of Colloid and Interface Science, v. 409, p. 52-58, 11/1/ 2013. ISSN 0021-9797.
• MALET, F. et al. Optical response of two-dimensional few-electron concentric double quantum rings: A local-spin-density-functional theory study. Physical Review B, v. 74, n. 19, Nov 2006. ISSN 1098-0121. Disponível em: < <Go to ISI>://WOS:000242409200018 >.
• MIDDLEMAN, S. The effect of induced air -flow on the spin coating of viscous liquids: Journal of Applied Physics. 62 1987.
• REN, Y.; ADEYEYE, A. O. Magnetic spin states and vortex stability control in elongated Ni(80)Fe(20) nanorings. Journal of Applied Physics, v. 105, n. 6, Mar 2009. ISSN 0021-8979. Disponível em: < <Go to ISI>://WOS:000264774000113 >.
• SRIVASTAVA, S. K.; GUPTA, B. D. A Multitapered Fiber-Optic SPR Sensor With Enhanced Sensitivity. Ieee Photonics Technology Letters, v. 23, n. 13, p. 923-925, Jul 1 2011. ISSN 1041-1135. Disponível em: < <Go to ISI>://WOS:000291678300006 >.