Saf Titanyum İmplantın Asit ve Alkali İşlemler ile Yüzey Modifikasyonu

Yıl 2015, Cilt: 15 Sayı: 3, 6 - 13, 30.12.2015

Egemen Ünal Melih Özçatal Şükrü Taktak , Atilla Evcin Yusuf Kayalı

https://doi.org/10.5578/fmbd.10294

Cited By: 3

Öz

Mevcut çalışmada, ticari saf titanyum numuneler biyouyumluluk açısından önem arz eden yüzey
pürüzlülüğünün sıvı temas açısı üzerine etkisini incelemek için değişik asit ve alkali çözeltilerine maruz
bırakılmıştır. Bu amaçla, titanyum yüzeyi 6 farklı asit ve alkali çözeltileri ile uzun süreli dağlanmıştır.
Yüzeyler mekanik profilometre, sıvı temas açısı ölçüm cihazı ve taramalı elektron mikroskobu (SEM) ile
incelenmiştir. Çalışma sonucunda, titanyum implant yüzeyindeki pürüzlülük değerinin artışı ile sıvı
temas açısının arttığı görülmüştür. Orijinal numune ile mukayese edildiğinde, 1K, 2K ve 3K kodlu
numunelerde yüzey pürüzlülüğü ve sıvı temas açısı düşmüş, 4K, 5K ve 6K kodlu numunelerde ise artma
eğilimi göstermiştir. Bu durum ilk 3 kimyasal işlemin titanyum yüzeyinde hidrofilik bir özellik
oluşturduğunun göstergesidir.

Anahtar Kelimeler

Saf titanyum, İmplant, Kimyasal modifikasyon, Sıvı temas açısı

Kaynakça

• Bagno, A., Bello, C., 2004. Surface treatments and roughness properties of Ti based biomaterials. Journal of Materials Science: Materials in Medicine, 15, 935-949.
• Bauer, S., Schmuki, P., von der Mark, K., Park, J., 2013. Engineering biocompatible implant surface: Part I: Materials and surfaces. Progress in Materials Science, 58, 261-326.
• Dearnley, P.A., 2005. A brief review of test methodologies for surface-engineered biomedical implant alloys. Surface and Coatings Technology, 198 (1-3), 483-490.
• Deligianni, D.D., Katsala, N., Ladas, S., Sotiropoulou, D., Amedee, J. and Missirlis, Y.F.,2001. Effect of surface roughness of the titanium alloy Ti6Al4V on human bone marrow cell response and on protein adsorption.Biomaterials,22 (11), 1241-1251.
• Esposito, M., Hirsch, J., Lekholm, U. and Thomsen, P., 1999. Differential diagnosis and treatment strategies for biologic complications and failing oral implants: a review of the literatüre.International Journal of Oral & Maxillofacial Implants, 14, 473-490.
• García-Alonso, M.C., Saldaña, L., Vallés, G., González- Carrasco, J.L., González-Cabrero, J., Martínez, M.E., Gil-Garaye, E. and Munuerae, L.,2003. In vitro corrosion behaviour and osteoblast response of thermally oxidised Ti6Al4V alloy. Biomaterials,24 (1), 19-26.
• Geetha, M., Singh, A.K., Asokamani, R. and Gogia, A.K., 2009. Ti based biomaterials, the ultimate choice for orthopaedic implants-A review, Progress in Materials Science, 54, 397-425.
• Gil, F.J., Padros, A., Manero, J.M., Aparicio, C., Nilsson, M. and Planell, J.A., 2002. Growth of bioactive surfaces on titanium and its alloys for orthopedic and dental implants. Materials Science and Engineering C,22, 53-60.
• Grigorescu, S., Pruna, V., Titorencu, I., Jinga, V.V., Mazare, A., Schmuki, P., Demetrescu, I., 2014. The two step nanotube formation on TiZr scaffolds for cell growth. Bioelectrochemistry. 98, 39-45.
• Guleryuz, H. and Cimenoğlu, H., 2004. Effect of thermal oxidation on corrosion and corrosion-wear behaviour of a Ti-6Al-4V alloy. Biomaterials, 25 (16), 3325-3333.
• Hallab, N.J., Bundy, K.J., O'Connor, K., Moses, R.L. and Jacobs, J.J., 2001. Evaluation of metallic and polymeric biomaterial surface energy and surface roughness characteristics for directed cell adhesion, Tissue Engineering, 2001, 7(1), 55-71.
• Hanawa, T., Asami, K., Asaoka, K., 1998. Repassivation of titanium and surface oxide film regenerated in simulated bioliquid.Journal of Biomedical Materials Research, 40(4), 530-538.
• Havıtcıoğlu, H., 2011. İmplant malzemelerinin yüzey özelliklerinin iyileştirilmesi.TOTBİD Dergisi, 10(2), 178-183.
• Huang, H.H., Ho, C.T., Lee, T.H., Lee, T.L., Liao, K.K. and Chen, F.L., 2004. Effect of surface roughness of ground Biomolecular Engineering. 21 (3-5), 93-97. initial cell adhesion,
• Jonn, B.P. and Young, K.K., 2000. Metalic Biomaterials. BiomedicalEngineering Handbook, Unit:37.
• Juodzbalys,G.,Sapragoniene,M. and Wennerrberg, A., 2003. NewAcidEtched Titanium Dental Implant Surface. Maxillofacial Journal, 5, 101-105. Baltic Dental and
• Klokkevold, P.R., Nishimura, R.D., Adachi, M. and Caputo, A., 1997. Osseointegration enhanced by chemical etching of titanium surface: atorque removal study in the rabbit. Clinical Oral Implants Research, 8(6), 442-447.
• Kokubo, T., Kushitani, H., Sakka, S., Kitsugi, T. and Yamamuro, T., 1990. Solutions able to reproduce in vivo surface-structure changes in bioactive glass- ceramic A-W.Journal of Biomedical Materials Research,24(6), 721-734.
• Komotori, J., Lee, B.J., Dong, H. and Dearnley, P.A., 2001. Corrosion response of surface engineered titanium alloys damaged by prior abrasion. Wear, 251 (1-12), 1239-1249.
• Kulkarni, M., Mazare, A., Schmuki, P., Iglič, A., 2015. Biomaterial surface modification of titanium and titanium Nanomedicine, 5, 111-136. medical applications.
• Larsson, C., Thomsen, P., Lausmaa, J., Rodahl, M., Kasemo, B. and Ericson, L.E., 1994. Bone response to surface modified titanium implants: studies on electropolished implants with different oxide thicknesses and morphology. Biomaterials,15, 1062- 1074.
• Liu, X., Chub, P.K. and Ding, C., 2004. Surface modification of titanium, titanium alloys, and related materials for biomedical applications.Materials Science and Engineering: R: Reports,47 (3-4), 49-121.
• Miwa, M., Nakajima, A., Fujishima, A.,Hashimoto, K. and Watanabe, T., 2000. Effects of the Surface Roughness on Sliding Angles of Water Droplets on Superhydrophobic Surfaces, Langmuir, 16 (13), 5754- 5760.
• Moruna, C., Espanol, M., Montufar, E., Mestres, G., Aparicio, C., Javier, G.F., Ginebra, M., 2013. Biomaterials Surface Science. Taubert, A., Mano, J.F., Rodriguez, Cabello, J.C. (eds.), Wiley-VCH Verlag, 337-374.
• Niinomi, M., 2003. Recent research and development in titanium alloys for biomedical applications and healthcare goods.Science and Technology of Advanced Materials. 4, 445-454.
• Nishiguchi, S., Fujibayashi, S., Kim, H.M., Kokubo, T. and Nakamura, T., 2003. Biology of alkali- and heat- treated titanium implants.Journal of Biomedical Materials Research Part A, 67A(1), 26-35.
• Nithyanandam, J., LalDas, S., Palanikumar, K., 2014. Surface Roughness Analysis in Turning of Titanium Alloy by Nanocoated Carbide Insert. Procedia Materials Science, 5, 2159-2168.
• Pan, J., Thierry, D. and Leygraf, C., 1996. Hydrogen peroxide toward enhanced oxide growth on titanium in PBS solution: Blue coloration and clinical relevance.Journal of Biomedical Materials Research, 30 (3), 393-402.
• Pilliar, R.M.,2003. Metals and Orthopaedic Implants-Past Successes, Challenges.Medical Device Materials, Procceedings of the Materials & Processes for Medical Device Conference, Ed. Shrivastava S., Anaheim C.A., 8-22.
• Ponsonnet, L., Reybier, K., Jaffrezic, N., Comte, V., Lagneau, C., Lissac, M. and Martelet, C., 2003. Relationship between surface properties (roughness, wettability) of titanium and titanium alloys and cell behavior.Materials Science and Engineering C, 23(4), 551–560.
• Qi, Y.M., Ma, B.H., Geng, Y.J., Deng, J.Y., Cui, C.X., 2014. Nanosurface modification of biomedical β titanium alloy for dental implant and its antibacterial property. Advanced Materials Research, 904, 142- 145.
• Ross, A.P., Webster, T.J., 2013. Anodizing color coded anodized Ti6Al4V medical devices for increasing bone cell functions. International Journal of Nanomedicine, 8, 109-117.
• Shah, A.K., Sinha, R.K., Hickok,N.J. and Tuan, R.S., 1999. High-resolution morphometric analysis of human osteoblastic cell adehesion on clinically relevant orthopedic alloys.Bone,24 (5), 499-506.
• Wälivaara, B., Aronsson, B.O., Rodahl, M., Lausmaa, J. and Tengvall, P., 1994. Titanium with different oxides: in vitro studies of protein adsorption and contact activation.Biomaterials,15 (10), 827-834.
• Wenzel, R.N., 1936. Resistance of solid surfaces to wetting by water. Industrial and engineering chemistry, 28(8), 988-994.