Koloidal Tek Tabaka Transferine Dayalı Metalik Nano Şablonların Biyosensör Yüzeyler Olarak Hazırlanması

Yıl 2020, Cilt: 20 Sayı: 2, 319 - 330, 20.05.2020

Numan Gözübenli

https://doi.org/10.35414/akufemubid.604735

Öz

Kat-kat (LbL) transfer tekniği, nanoyapılı malzemelerin hazırlanmasında yaygın olarak kullanılan basit, çok yönlü bir yaklaşım olarak dikkat çekmektedir. Bu süreç, polimerler, nanopartiküller, lipitler, proteinler veya organik boya molekülleri gibi bileşenlerin sırayla biriktirilmesi işlemine dayalı olup, bunların üç boyutlu kristal dizilimlerinden, serbest duran (iki boyutlu) şablonlar elde etmede kullanılan katmanların tek tek uzaklaştırılması sürecidir. Her ne kadar malzeme özelliklerinin (örn. boyut, bileşim, kalınlık, geçirgenlik, işlev, vb.) LbL transferinde hazırlanan malzemenin kendisi tarafından sağlanmasına rağmen, şablonların morfolojisi ve bileşimi de üretilen malzemelerin özelliklerinin ve dolayısıyla potansiyel uygulamaların belirlenmesinde önemli bir rol oynar. Bu çalışmada, çok çeşitli yüzeylerde tek katmanlı, fonksiyonel silika koloidal kristallerin ölçeklenebilir bir şekilde imal edilmesini sağlayan basit bir koloidal transfer teknolojisi rapor edilmiştir. Olağandışı bir yapıya sahip iki boyutlu koloidal kristal dizilimlerin ilk önce cam bir yüzey üzerine bir döner (spin)-kaplama tekniği ile kaplanması sağlanır. Koloidal kristal tabakalar üzerine dökülen bir poliüretan (PÜ) filmi, üzerleri açık partikül dizilerini çeşitli yüzeylere aktarabilmek için kullanılmaktadır. Transfer edilen tek tabakalı koloidal kristalin birim aralığı, PÜ-silika kompozit filminin çeşitli süreler boyunca metalik kaplama ile veya termal olarak işlenmesiyle kolayca ayarlanabilir. Bu çalışmada; yapısal şablon olarak transfer edilen tek tabakalı temassız koloidal kristallerin, altın kaplanmış nano kürecikler olarak periyodik dizili sensör yüzeyler olarak geliştirilebileceği kanıtlandı. Elde edilen plazmonik dizinin, optiksel biyo algılayıcılarda sıkça kullanılmakta olan benzentiyol molekülleri için yüksek seçicilikte Raman saçılma piklerine sahip olduğu gösterilmiştir.

Anahtar Kelimeler

Döner (spin) kaplama, Koloidal silika kristali, Fotonik kristal, Nanoküreler, Nanokabuklar

Destekleyen Kurum

HARRAN ÜNİVERSİTESİ

Proje Numarası

18206

Teşekkür

Bu proje, Harran Üniversitesi, BAP tarafından, Biyomoleküllerin saflaştırılmasında kullanılacak manyetik nano partiküllerin üretimi başlıklı, 18206 nolu proje ile desteklenmiştir. Ayrıca makalede destek veren Harran Üniversitesi Bölüm Mensuplarına teşekkür ederim.

Preparation of Metalic Nano-Templates Based on Transfer of Colloidal Monolayer as Biosensor Surfaces

Öz

Layer-by-layer (LbL) transfer technique stands out as a simple, versatile approach commonly used in the preparation of nanostructured materials. This process is based on the sequential deposition of components such as polymers, nanoparticles, lipids, proteins, or organic dye molecules, and the process of removing individual layers from their three-dimensional crystal arrays to obtain free-standing templates. Although the material properties (eg size, composition, thickness, permeability, function, etc.) are provided by the material itself prepared in the LbL transfer, the morphology and composition of the templates also play an important role in determining the properties of the materials produced and hence in the potential applications. In this study, a simple colloidal transfer technology, which enables the scalable production of monolayer functional silica colloidal crystals on a wide variety of surfaces, is reported. The two-dimensional colloidal crystal arrays having an unusual structure are first coated onto a glass surface by a spin-coating technique. A polyurethane (PU) film cast over the colloidal crystal layer is used to transfer uncoated particle arrays into various surfaces. The unit spacing of the transferred monolayer colloidal crystal can be easily adjusted by thermal process or with metallic coating of the PU-silica composite film for various periods of time. In this study; it has been proved that monolayer non-close colloidal crystals transferred as structural templates can be developed as highly ordered array sensor surfaces containing gold-coated nanospheres. The resulting plasmonic array has been shown to have high selectivity Raman scattering peaks for benzenthiol molecules commonly used in optical biosensors.

Anahtar Kelimeler

Spin coating, Colloidal silica crystal, Photonic crystal, Nanospheres, Nanoshells

Proje Numarası

18206

Kaynakça

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