Uyku Apnesi Teşhisine Yeni Bir Bakış Açısı: PSSA-g-PANI tabanlı SAW Sensörü Kullanarak İzopren Tespiti

Yıl 2022, Cilt: 22 Sayı: 1, 16 - 22, 28.02.2022

Cihat Tasaltın , Gülsen Baytemir , Nevin Taşaltın

https://doi.org/10.35414/akufemubid.931030

Öz

Obstrüktif Uyku Apne Sendromu (OSAS) tarafından tetiklenen hücresel metabolik değişiklikler, nefeste OSAS'ın biyobelirteci olarak izopren saptanarak invazif olarak tespit edilir. Uykuya dalındığında izopren seviyesi 3 ppm'nin üzerine çıkmaya başlar. Bu nedenle, normal koşullar altında solunan nefeste izopren seviyelerinin izlenmesi, uyku apnesi gibi uyku bozukluklarını tespit etmek, izlemek ve kontrol etmek için invazif olmayan bir yöntem sağlayabilir. Bu çalışmada, PSSA-g-PANI tabanlı SAW gaz sensörleri hazırlanmış ve izopren gaza karşı test edilmiştir. Sensör ölçümleri, PSSA-g-PANI tabanlı SAW tipi sensörün yüksek hassasiyetle (1-150) ppm izopren gazı algıladığını ve dolayısıyla PSSA-g-PANI tabanlı SAW tipi sensörün uyku apnesinin izlenmesini ve kontrolünü sağlayabileceğini ortaya koymaktadır.

Anahtar Kelimeler

Uyku apnesi, Sensor, Solunan nefes, Izopren

Destekleyen Kurum

Tübitak

Proje Numarası

120N816

A New Perspective towards Diagnosis of Sleep Apnea: Isoprene Detection Using PSSA-g-PANI based SAW Sensor

Öz

Cellular metabolic changes triggered by Obstructive Sleep Apnea Syndrome (OSAS) are detected invasively by detecting isoprene as a biomarker of OSAS in the breath. When falling asleep, isoprene level begins to increase above 3 ppm. Therefore, monitoring isoprene levels in exhaled breath under normal conditions may provide a non-invasive method to detect, monitor, and control sleep disorders such as sleep apnea. In this study, PSSA-g-PANI based SAW gas sensors were prepared and tested against isoprene gas. Sensor measurements reveal that PSSA-g-PANI based SAW type sensor detected (1-150) ppm isoprene gas with high sensitivity and thus PSSA-g-PANI based SAW type sensor may enable monitor and control of sleep apnea.

Anahtar Kelimeler

Sleep apnea, Sensor, Exhaled breath, Isoprene

Proje Numarası

120N816

Kaynakça

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