Araştırma Makalesi
BibTex RIS Kaynak Göster
Yıl 2020, Cilt: 35 Sayı: 1, 44 - 49, 30.06.2020
https://doi.org/10.28955/alinterizbd.740928

Öz

Kaynakça

  • Al-Saadi, N.H.M., Ahmad, N.S., Saeed, S.E., 2009. Determination of some chemical compounds and the effect of oil extract from orange peel on some pathogens. Journal of Kerbala University, 7(2):33-39.
  • Bampidis, V.A., and Robinson, P.H., 2006. Citrus by-products as ruminant feeds: a review. Animal Feed Sci Technol, 128: 175-217.
  • Bauer, K., Garbe, D., and Surburg, H.. 2001. "Common Fragrance and Flavor Materials", 4th Ed, Wiley VCH, ISBN 3-527-30364-2. 189.
  • Bölükbasi, S.C., Kaynar, Ö., Erhan, M.K., and Ürüsan, H., 2009. The effect of feeding nigella sativa oil on laying hen performance, cholesterol and some proteins ratio of egg yolk and escherichia coli count in feces. Archive für Geflügelkunde 73(3): 167-172.
  • Bölükbasi S.C., and Erhan M.K., 2007. Effect of dietary thyme (Thymus vulgaris) on laying hens performance and escherichia coli (E. Coli)_concentration in feces. International Journal Natural and Engineering Science 1(2): 55-58.
  • Bruggeman, G., Deschepper, K., and Molly, K,. 2002. Plant antibacterials suit modern production. Feed Mix Magazine 10:18.
  • Canan, İ., Gündoğdu, M., Seday, U., Oluk, C.A., Karaşahin, Z., Eroğlu, Ç.E., Yazıcı, E., Ünlü, M., 2016. Determination of antioxidant, total phenolic, total carotenoid, lycopene, ascorbic acid and sugar contents of Citrus species and mandarin hybrids. Turkish Journal of Agriculture and Forestry, 40: 894-899.
  • Chaudhary, S.C., Siddiqui, M.S., Athar, M., and Alam, M.S., 2012. d-Limonene modulates inflammation, oxidative stress and Ras-ERK pathway to inhibit murine skin tumorigenesis. Hum. Exp. Toxicol. 31:798–811. doi: 10.1177/0960327111434948.
  • Chen T.C., Fonseca C.O., Schönthal A.H. Preclinical development and clinical use of perillyl alcohol for chemoprevention and cancer therapy. Am. J. Cancer Res. 2015;5:1580–1593. [PMC free article] [PubMed] [Google Scholar]
  • Crowell, P.L., and Gould, M.N., 1994. Chemoprevention and therapy of cancer by d-limonene. Crit. Rev. Oncog. 5:1–22. doi: 10.1615/CritRevOncog.v5.i1.10.
  • Demir, E., Kocaoglu, S., Cetin H, et al. 2009. Antigenotoxic effects of citrus aurentium l. fruit peel oil on mutagenicity of two alkylating agents and two metals in the drosophila wing spot test. Environ Mol Mutagen, 50: 483-8
  • Erhan M.K., and Bölükbaşı Ş.C., 2017. Citrus Peel Oils Supplementation in Broiler Diet: Effects on Performance, Jejunum Microflora and Jejunum Morphology; Rev. Bras. Cienc. Avic. vol.19 no.spe Campinas Jan./Mar. http://dx.doi.org/10.1590/1806-9061-2016-0274
  • Erhan, M.K., and Bölükbaşı Aktaş Ş.C., 2017. [Effects of Citrus Peel Oils on Tissue Fatty Acid Composition and Shelf Life in Broilers. Atatürk Üniversitesi Vet. Bil. Derg. 12(2): 157-166 DOI:10.17094/ataunivbd.347682
  • Fidrianny, I., Harnovi, M., Insanu, M., 2014. Evaluation Of Antioxidant Activities From Various Extracts Of Sweet Orange Peels Using Dpph, Frap Assays And Correlation With Phenolic, Flavonoid, Carotenoid Content. Asian J Pharm Clin Res, 7(3):186-190.
  • Fisher, K., Phillips, C., 2008. Potential Antimicrobial Uses of Essential Oils in Food: Is Citrus the Answer? Trends Food Sci Technol. 19: 156. https://doi.org/10.1016/j.tifs.2007.11.006
  • Giil, C., 1999. Herbs and plant extracts as growth enhancers. Feed Int. (April) 20-23.
  • Giil, C., 1999. Herbs and plant extracts as growth enhancers. Feed Int. (April) 20-23.
  • Güler, T., Ertaş, O.N., Çiftçi, M., and Dalkılıç, B., 2005. The effect of coriander Sativum L. seeds on performance in Japanese quail. South African Vet and Anim Sci. 35(4): 260-266
  • Hamdan, D., Ashour, M.L., Mulyaningsih, S., et al., 2013. Chemical composition of the essential oils of variegated pink-fleshed lemon (Citrus x limon L. Burm. f.) and their anti-inammatory and antimicrobial activities. Z Naturforsch C, 68: 275-84
  • Hosseinimehr, S.J., and Karami, M., 2005. Citrus extract modulates genotoxicity induced by cyclophosphamide in mice bone marrow cells. J Pharm Pharmacol, 57: 505-9.
  • Im, S.J., Kim, J.H., and Kim, M.Y., 2014. Evaluation of bioactive components and antioxidant and anticancer properties of citrus wastes generated during bioethanol production. Nat Prod Commun, 9: 483-6
  • Janati, S. S. F., Beheshti, H. R., Feizy, J., Fahim, N. K., 2012. Chemical Composition Of Lemon (Citrus Limon) And Peels Its Considerations As Animal Food. Gıda 37 (5): 267-271.
  • Jayaprakasha G.K., Murthy K.N.C., Uckoo R.M., Patil B.S. Chemical composition of volatile oil from Citrus limettioides and their inhibition of colon cancer cell proliferation. Ind. Crop. Prod. 2013;45:200–207. doi: 10.1016/j.indcrop.2012.12.020. [CrossRef] [Google Scholar]
  • Jia S.S., Xi G.P., Zhang M., Chen Y.B., Lei B., Dong X.S., Yang Y.M. Induction of apoptosis by d-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells. Oncol. Rep. 2013;29:349–354. [PubMed] [Google Scholar]
  • Kafa, G., Tuzcu, Ö., and Yeşiloğlu, T., 2009. Determination of yield, quality, and some plant characteristics of some orange types obtained by selection under Adana conditions. Alatarım, 8(1): 21-29.
  • Kamel, C,. 2001. Tracing modes of action and the role of plant extracts in non-ruminants. In: Garnsworthy PC, Wiseman J, editors. Recent advances in animal nutrition. Nottingham: University Press; 135-150.
  • Kutlu, H.R., and Görgülü, M., 2001. Alternatives for Antibiotics and Growth Factors Used as Feed Additives in Poultry Feed. Yem Magazin Dergisi. 27: 45-62.
  • Lai, C.S., Li, S., Miyauchi, Y., et al., 2013. Potent anti-cancer effects of citrus peel flavonoids in human prostate xenograft tumors. Food Funct, 4: 944-9
  • Lashkari, S., and Taghizadeh, A., (2013). Nutrient digestibility and evaluation of protein and carbohydrate fractionation of citrus by-products. J Anim Physiol Anim Nutr (Berl), 97, 701-9.
  • Lesgards, J.F., Baldovini, N., Vidal, N., and Pietri, S., 2014. Anticancer activities of essential oils constituents and synergy with conventional therapies: A review. Phytother. Res. 28:1423–1446. doi: 10.1002/ptr.5165
  • Mauro, M., Catanzaro, I., Naselli, F., Sciandrello, G., and Caradonna, F., 2013. Abnormal mitotic spindle assembly and cytokinesis induced by d-limonene in cultured mammalian cells. Mutagenesis. 28:631–635. doi: 10.1093/mutage/get040
  • Min-Hsiung, P., 2009. Chemopreventive effects of natural dietary compounds on cancer development. Second Symposium on FranceTaiwan Frontiers of Science Tentative Program.
  • Mitsch, P., Zitterl-Eglseer, K., Köhler, B., Gabler, C., Losa, R., and Zimpernik, I., 2004. The effect of two different blends of essential oil components on the proliferation of clostridium perfringens in the intestines of broiler chickens. Poultry Science 83(4): 669-675.
  • Murthy K.N.C., Jayaprakasha G.K., Patil B.S. d-Limonene rich volatile oil from blood oranges inhibits angiogenesis, metastasis and cell death in human colon cancer cells. Life Sci. 2012;91:429–439. doi: 10.1016/j.lfs.2012.08.016. [PubMed] [CrossRef] [Google Scholar]
  • Nir, İ., and Şenköylü, N., 2000. Feed Additives Supporting Digestion in Poultry Trakya Üniversitesi,Tekirdağ Ziraat Fakültesi, Tekirdağ
  • Oboh, G., Ademosun, A.O., 2012. Characterization of the antioxidant properties of phenolic extracts from some citrus peels. J Food Sci Technol 49(6): 729–736.
  • Roberto, D., Micucci, P., Sebastian, T., Graciela, F., and Anesini, C., 2010. Antioxidant activity of limonene on normal murinelymphocytes: relation to H2O2 modulation and cell proliferation. Basic Clin Pharmacol. Toxicol. 106. 38-44.
  • Steuer, B., Schulz, H., and Läger, E. 2001. Classification and analysis of citrus oils by NIR spectroscopy Food Chem., 72: 113. https://doi.org/10.1016/S0308-8146(00)00209-0
  • Stone, W.L., Krishnan, K., Campbell, S.E., and Palau, V.E., 2014. The role of antioxidants and pro-oxidants in colon cancer. World J. Gastrointest. Oncol. 6:55–66.
  • Sultana, S., Asif, H.M., Nazar, H.M., et al., 2014. Medicinal plants combating against cancer--a green anticancer approach. Asian Pac J Cancer Prev, 15: 4385-94
  • Suttirak, W., and Manurakchinakorn S., 2014. In vitro antioxidant properties of mangosteen peel extract. J. Food Sci. Technol. 51: 3546–3558. doi: 10.1007/s13197-012-0887-5.
  • Turhan, İ., Tetik, N., Karhan, M., 2006. [Obtaining citrus shell oils and their use in food industry]. Gıda Teknolojileri Elektronik Dergisi, 3:71-77.
  • Vigushin, D.M., Poon, G.K., Boddy, A., English, J., Halbert, G.W., Pagonis, C., Jarman, M., and Coombes, R.C., 1998. Cancer Research Campaign Phase I/II Clinical Trials Committee Phase I and pharmacokinetic study of d-limonene in patients with advanced cancer. Cancer Chemother. Pharmacol. 42:111–117. doi: 10.1007/s002800050793
  • Wang, Y.C., Chuang, Y.C., Hsu, H.W., 2008. The flavonoid, carotenoid and pectin content in peels of citrus cultivated in Taiwan. Food Chem., 106: 277–284.
  • Wilkins, M.R., Widmer, W.W., Grohmann, K., 2007. Simultaneous saccharification and fermentation of citrus peel waste by Saccharomyces cerevisiae to produce ethanol. Process Biochemistry 42: 1614–1619.
  • Yapo, B. M., 2009. Biochemical Characteristics and Gelling Capacity of Pectin from Yellow Passion Fruit Rind as Affected by Acid Extractant Nature. J. Agric. Food Chem., 57: 1572–1578.
  • Yavuz, H.M., 2001. Basic Principles of Nutrition of Farm Animals and Some Scientific Approaches in Feed Production. Farmavet Publishing, Istanbul.

The Potential of Orange Peel Oil as a Suppressor of Cell Proliferation in Animal Feed and Human Nutrition: An Experimental Study

Yıl 2020, Cilt: 35 Sayı: 1, 44 - 49, 30.06.2020
https://doi.org/10.28955/alinterizbd.740928

Öz

This study aimed to investigate the in vitro cytotoxic activities of orange peel oil on HaCaT cell lines by using an MTT cytotoxicity assay after administering orange peel oil at different doses and time-points. Our objective was to assess the in vitro cytotoxic activities of orange peel oil on HaCaT cell lines.‎ Cell viability was determined with the MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide] assays. The HaCaT cells (100 µL) were cultured in plates and treated with different concentrations of orange peel oil (25 µM, 50 µM, 100 µM, 150 µM and 200 µM) for durations of 24 and 48 hours. Cell death was determined by collecting and staining with 0.4% Trypan blue for 5 minutes at room temperature, followed by microscopic examination. There was a significant difference between the doses concerning ‎both time zones (p <0.05). There was a significant (p<0.05) difference between the control group and all other doses, including 200 µl/mL and 25 µl/mL, 50 µl/mL, 100 ‎µl/mL, and 20% DMSO. Orange peel oil showed toxic effects at all dose levels and time points when compared with the control group. According to the results of our research, and in light of previous investigations, it can be said that orange shell oil may have protective effects such as anti-cancer, anti-microbial, and antioxidant properties, and thus, may be used in human and animal nutrition.

Kaynakça

  • Al-Saadi, N.H.M., Ahmad, N.S., Saeed, S.E., 2009. Determination of some chemical compounds and the effect of oil extract from orange peel on some pathogens. Journal of Kerbala University, 7(2):33-39.
  • Bampidis, V.A., and Robinson, P.H., 2006. Citrus by-products as ruminant feeds: a review. Animal Feed Sci Technol, 128: 175-217.
  • Bauer, K., Garbe, D., and Surburg, H.. 2001. "Common Fragrance and Flavor Materials", 4th Ed, Wiley VCH, ISBN 3-527-30364-2. 189.
  • Bölükbasi, S.C., Kaynar, Ö., Erhan, M.K., and Ürüsan, H., 2009. The effect of feeding nigella sativa oil on laying hen performance, cholesterol and some proteins ratio of egg yolk and escherichia coli count in feces. Archive für Geflügelkunde 73(3): 167-172.
  • Bölükbasi S.C., and Erhan M.K., 2007. Effect of dietary thyme (Thymus vulgaris) on laying hens performance and escherichia coli (E. Coli)_concentration in feces. International Journal Natural and Engineering Science 1(2): 55-58.
  • Bruggeman, G., Deschepper, K., and Molly, K,. 2002. Plant antibacterials suit modern production. Feed Mix Magazine 10:18.
  • Canan, İ., Gündoğdu, M., Seday, U., Oluk, C.A., Karaşahin, Z., Eroğlu, Ç.E., Yazıcı, E., Ünlü, M., 2016. Determination of antioxidant, total phenolic, total carotenoid, lycopene, ascorbic acid and sugar contents of Citrus species and mandarin hybrids. Turkish Journal of Agriculture and Forestry, 40: 894-899.
  • Chaudhary, S.C., Siddiqui, M.S., Athar, M., and Alam, M.S., 2012. d-Limonene modulates inflammation, oxidative stress and Ras-ERK pathway to inhibit murine skin tumorigenesis. Hum. Exp. Toxicol. 31:798–811. doi: 10.1177/0960327111434948.
  • Chen T.C., Fonseca C.O., Schönthal A.H. Preclinical development and clinical use of perillyl alcohol for chemoprevention and cancer therapy. Am. J. Cancer Res. 2015;5:1580–1593. [PMC free article] [PubMed] [Google Scholar]
  • Crowell, P.L., and Gould, M.N., 1994. Chemoprevention and therapy of cancer by d-limonene. Crit. Rev. Oncog. 5:1–22. doi: 10.1615/CritRevOncog.v5.i1.10.
  • Demir, E., Kocaoglu, S., Cetin H, et al. 2009. Antigenotoxic effects of citrus aurentium l. fruit peel oil on mutagenicity of two alkylating agents and two metals in the drosophila wing spot test. Environ Mol Mutagen, 50: 483-8
  • Erhan M.K., and Bölükbaşı Ş.C., 2017. Citrus Peel Oils Supplementation in Broiler Diet: Effects on Performance, Jejunum Microflora and Jejunum Morphology; Rev. Bras. Cienc. Avic. vol.19 no.spe Campinas Jan./Mar. http://dx.doi.org/10.1590/1806-9061-2016-0274
  • Erhan, M.K., and Bölükbaşı Aktaş Ş.C., 2017. [Effects of Citrus Peel Oils on Tissue Fatty Acid Composition and Shelf Life in Broilers. Atatürk Üniversitesi Vet. Bil. Derg. 12(2): 157-166 DOI:10.17094/ataunivbd.347682
  • Fidrianny, I., Harnovi, M., Insanu, M., 2014. Evaluation Of Antioxidant Activities From Various Extracts Of Sweet Orange Peels Using Dpph, Frap Assays And Correlation With Phenolic, Flavonoid, Carotenoid Content. Asian J Pharm Clin Res, 7(3):186-190.
  • Fisher, K., Phillips, C., 2008. Potential Antimicrobial Uses of Essential Oils in Food: Is Citrus the Answer? Trends Food Sci Technol. 19: 156. https://doi.org/10.1016/j.tifs.2007.11.006
  • Giil, C., 1999. Herbs and plant extracts as growth enhancers. Feed Int. (April) 20-23.
  • Giil, C., 1999. Herbs and plant extracts as growth enhancers. Feed Int. (April) 20-23.
  • Güler, T., Ertaş, O.N., Çiftçi, M., and Dalkılıç, B., 2005. The effect of coriander Sativum L. seeds on performance in Japanese quail. South African Vet and Anim Sci. 35(4): 260-266
  • Hamdan, D., Ashour, M.L., Mulyaningsih, S., et al., 2013. Chemical composition of the essential oils of variegated pink-fleshed lemon (Citrus x limon L. Burm. f.) and their anti-inammatory and antimicrobial activities. Z Naturforsch C, 68: 275-84
  • Hosseinimehr, S.J., and Karami, M., 2005. Citrus extract modulates genotoxicity induced by cyclophosphamide in mice bone marrow cells. J Pharm Pharmacol, 57: 505-9.
  • Im, S.J., Kim, J.H., and Kim, M.Y., 2014. Evaluation of bioactive components and antioxidant and anticancer properties of citrus wastes generated during bioethanol production. Nat Prod Commun, 9: 483-6
  • Janati, S. S. F., Beheshti, H. R., Feizy, J., Fahim, N. K., 2012. Chemical Composition Of Lemon (Citrus Limon) And Peels Its Considerations As Animal Food. Gıda 37 (5): 267-271.
  • Jayaprakasha G.K., Murthy K.N.C., Uckoo R.M., Patil B.S. Chemical composition of volatile oil from Citrus limettioides and their inhibition of colon cancer cell proliferation. Ind. Crop. Prod. 2013;45:200–207. doi: 10.1016/j.indcrop.2012.12.020. [CrossRef] [Google Scholar]
  • Jia S.S., Xi G.P., Zhang M., Chen Y.B., Lei B., Dong X.S., Yang Y.M. Induction of apoptosis by d-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells. Oncol. Rep. 2013;29:349–354. [PubMed] [Google Scholar]
  • Kafa, G., Tuzcu, Ö., and Yeşiloğlu, T., 2009. Determination of yield, quality, and some plant characteristics of some orange types obtained by selection under Adana conditions. Alatarım, 8(1): 21-29.
  • Kamel, C,. 2001. Tracing modes of action and the role of plant extracts in non-ruminants. In: Garnsworthy PC, Wiseman J, editors. Recent advances in animal nutrition. Nottingham: University Press; 135-150.
  • Kutlu, H.R., and Görgülü, M., 2001. Alternatives for Antibiotics and Growth Factors Used as Feed Additives in Poultry Feed. Yem Magazin Dergisi. 27: 45-62.
  • Lai, C.S., Li, S., Miyauchi, Y., et al., 2013. Potent anti-cancer effects of citrus peel flavonoids in human prostate xenograft tumors. Food Funct, 4: 944-9
  • Lashkari, S., and Taghizadeh, A., (2013). Nutrient digestibility and evaluation of protein and carbohydrate fractionation of citrus by-products. J Anim Physiol Anim Nutr (Berl), 97, 701-9.
  • Lesgards, J.F., Baldovini, N., Vidal, N., and Pietri, S., 2014. Anticancer activities of essential oils constituents and synergy with conventional therapies: A review. Phytother. Res. 28:1423–1446. doi: 10.1002/ptr.5165
  • Mauro, M., Catanzaro, I., Naselli, F., Sciandrello, G., and Caradonna, F., 2013. Abnormal mitotic spindle assembly and cytokinesis induced by d-limonene in cultured mammalian cells. Mutagenesis. 28:631–635. doi: 10.1093/mutage/get040
  • Min-Hsiung, P., 2009. Chemopreventive effects of natural dietary compounds on cancer development. Second Symposium on FranceTaiwan Frontiers of Science Tentative Program.
  • Mitsch, P., Zitterl-Eglseer, K., Köhler, B., Gabler, C., Losa, R., and Zimpernik, I., 2004. The effect of two different blends of essential oil components on the proliferation of clostridium perfringens in the intestines of broiler chickens. Poultry Science 83(4): 669-675.
  • Murthy K.N.C., Jayaprakasha G.K., Patil B.S. d-Limonene rich volatile oil from blood oranges inhibits angiogenesis, metastasis and cell death in human colon cancer cells. Life Sci. 2012;91:429–439. doi: 10.1016/j.lfs.2012.08.016. [PubMed] [CrossRef] [Google Scholar]
  • Nir, İ., and Şenköylü, N., 2000. Feed Additives Supporting Digestion in Poultry Trakya Üniversitesi,Tekirdağ Ziraat Fakültesi, Tekirdağ
  • Oboh, G., Ademosun, A.O., 2012. Characterization of the antioxidant properties of phenolic extracts from some citrus peels. J Food Sci Technol 49(6): 729–736.
  • Roberto, D., Micucci, P., Sebastian, T., Graciela, F., and Anesini, C., 2010. Antioxidant activity of limonene on normal murinelymphocytes: relation to H2O2 modulation and cell proliferation. Basic Clin Pharmacol. Toxicol. 106. 38-44.
  • Steuer, B., Schulz, H., and Läger, E. 2001. Classification and analysis of citrus oils by NIR spectroscopy Food Chem., 72: 113. https://doi.org/10.1016/S0308-8146(00)00209-0
  • Stone, W.L., Krishnan, K., Campbell, S.E., and Palau, V.E., 2014. The role of antioxidants and pro-oxidants in colon cancer. World J. Gastrointest. Oncol. 6:55–66.
  • Sultana, S., Asif, H.M., Nazar, H.M., et al., 2014. Medicinal plants combating against cancer--a green anticancer approach. Asian Pac J Cancer Prev, 15: 4385-94
  • Suttirak, W., and Manurakchinakorn S., 2014. In vitro antioxidant properties of mangosteen peel extract. J. Food Sci. Technol. 51: 3546–3558. doi: 10.1007/s13197-012-0887-5.
  • Turhan, İ., Tetik, N., Karhan, M., 2006. [Obtaining citrus shell oils and their use in food industry]. Gıda Teknolojileri Elektronik Dergisi, 3:71-77.
  • Vigushin, D.M., Poon, G.K., Boddy, A., English, J., Halbert, G.W., Pagonis, C., Jarman, M., and Coombes, R.C., 1998. Cancer Research Campaign Phase I/II Clinical Trials Committee Phase I and pharmacokinetic study of d-limonene in patients with advanced cancer. Cancer Chemother. Pharmacol. 42:111–117. doi: 10.1007/s002800050793
  • Wang, Y.C., Chuang, Y.C., Hsu, H.W., 2008. The flavonoid, carotenoid and pectin content in peels of citrus cultivated in Taiwan. Food Chem., 106: 277–284.
  • Wilkins, M.R., Widmer, W.W., Grohmann, K., 2007. Simultaneous saccharification and fermentation of citrus peel waste by Saccharomyces cerevisiae to produce ethanol. Process Biochemistry 42: 1614–1619.
  • Yapo, B. M., 2009. Biochemical Characteristics and Gelling Capacity of Pectin from Yellow Passion Fruit Rind as Affected by Acid Extractant Nature. J. Agric. Food Chem., 57: 1572–1578.
  • Yavuz, H.M., 2001. Basic Principles of Nutrition of Farm Animals and Some Scientific Approaches in Feed Production. Farmavet Publishing, Istanbul.
Toplam 47 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Ziraat, Veterinerlik ve Gıda Bilimleri
Bölüm Araştırma Makaleleri
Yazarlar

Muhammet Kuddusi Erhan Bu kişi benim 0000-0003-4115-8747

Yayımlanma Tarihi 30 Haziran 2020
Kabul Tarihi 3 Mart 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 35 Sayı: 1

Kaynak Göster

APA Erhan, M. K. (2020). The Potential of Orange Peel Oil as a Suppressor of Cell Proliferation in Animal Feed and Human Nutrition: An Experimental Study. Alinteri Journal of Agriculture Science, 35(1), 44-49. https://doi.org/10.28955/alinterizbd.740928
AMA Erhan MK. The Potential of Orange Peel Oil as a Suppressor of Cell Proliferation in Animal Feed and Human Nutrition: An Experimental Study. Alinteri Journal of Agriculture Science. Haziran 2020;35(1):44-49. doi:10.28955/alinterizbd.740928
Chicago Erhan, Muhammet Kuddusi. “The Potential of Orange Peel Oil As a Suppressor of Cell Proliferation in Animal Feed and Human Nutrition: An Experimental Study”. Alinteri Journal of Agriculture Science 35, sy. 1 (Haziran 2020): 44-49. https://doi.org/10.28955/alinterizbd.740928.
EndNote Erhan MK (01 Haziran 2020) The Potential of Orange Peel Oil as a Suppressor of Cell Proliferation in Animal Feed and Human Nutrition: An Experimental Study. Alinteri Journal of Agriculture Science 35 1 44–49.
IEEE M. K. Erhan, “The Potential of Orange Peel Oil as a Suppressor of Cell Proliferation in Animal Feed and Human Nutrition: An Experimental Study”, Alinteri Journal of Agriculture Science, c. 35, sy. 1, ss. 44–49, 2020, doi: 10.28955/alinterizbd.740928.
ISNAD Erhan, Muhammet Kuddusi. “The Potential of Orange Peel Oil As a Suppressor of Cell Proliferation in Animal Feed and Human Nutrition: An Experimental Study”. Alinteri Journal of Agriculture Science 35/1 (Haziran 2020), 44-49. https://doi.org/10.28955/alinterizbd.740928.
JAMA Erhan MK. The Potential of Orange Peel Oil as a Suppressor of Cell Proliferation in Animal Feed and Human Nutrition: An Experimental Study. Alinteri Journal of Agriculture Science. 2020;35:44–49.
MLA Erhan, Muhammet Kuddusi. “The Potential of Orange Peel Oil As a Suppressor of Cell Proliferation in Animal Feed and Human Nutrition: An Experimental Study”. Alinteri Journal of Agriculture Science, c. 35, sy. 1, 2020, ss. 44-49, doi:10.28955/alinterizbd.740928.
Vancouver Erhan MK. The Potential of Orange Peel Oil as a Suppressor of Cell Proliferation in Animal Feed and Human Nutrition: An Experimental Study. Alinteri Journal of Agriculture Science. 2020;35(1):44-9.