Status of Reaching LDL Goals In Diabetic Patıents And Frequency Of Statin Treatment Compliance

Yıl 2012, Cilt: 12 Sayı: 3, 122 - 123, 01.03.2012

Ahmet Keskin

https://izlik.org/JA46RA47PU

Öz

Aim: Our aim was to evaluate the frequency of patients

with diabetes mellitus which reached the LDL cholesterol

goals and their competence with the statin treatment.

Method: LDL cholesterol levels were evaluated and reasons which effect the reaching the LDL goals were asked.

Results: 106 diabetic patients were included to the study.

Only %28.3 of such patients were at the LDL goal. Most

of these patients were not compatible with their statin

treatment and were effected with the statin arguments

in media.

Discussion: Statin treatment is important for the cardiovascular treatment. So that patients must be questioned

about their compliance to their treatment.

Anahtar Kelimeler

Diabetes Mellitus , cholesterol , statin

Diyabetes Mellitus Hastalarında Hedef LDL Kolesterol Düzeylerine Ulaşma Durumu ve Statin Tedavisine Uyum Sıklığı

https://izlik.org/JA46RA47PU

Öz

Amaç: 

Diyabetes Mellitus (DM) hastalarında hedef LDL kolesterol düzeylerine ulaşma oranı ve statin tedavisine uyum ile ilişkisini araştırmak.

Metod:

Çalışmaya katılan hastaların LDL kolesterol düzeylerine bakıldı ve hedef değerlere ulaşamama nedenleri sorgulandı.

Sonuçlar:

Çalışmaya 106 DM hastası dahil edildi. Hastaların %28,3’ü hedef LDL değerlerine sahipti. Hastaların büyük bir çoğunluğu statin tedavisine uyumsuzdu ve medyadaki statin tartışmalarından da etkilenmişti.

Tartışma: 

Statinlerin kardiyovasküler korumada önemlidir. Bu yüzden bu hastaların tedaviye uyumları açısından da değerlendirilmesi gereklidir.

Anahtar Kelimeler

Diabetes mellitus , kolesterol , statin

Kaynakça

• 1. American Diabetes Association. Et al. Standards of medical care in diabetes--2012. Diabetes Care. 2012 Jan;35 Suppl 1:S11-63.
• 2. Türk Endokrinoloji ve Metabolizma Derneği Diabetes Mellitus ve Komplikasyonlarının Tanı, Tedavi ve İzlem Klavuzu 2011- http://www. turkendokrin.org/files/pdf/diabetes_klvz2011_web.pdf (05.08.12)
• 3. Sattar N, Preiss D. Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet. 2010 Feb 27;375(9716):735-742.
• 4. Liao JK, Is Statin Discontinuation an Option in Patients Who Have Had a Stroke? Nat Clin Pract Neurol. 2008;4(1):18-19.
• 5. Blanco M, Nombela F. Statin treatment withdrawal in ischemic stroke: a controlled randomized study. Neurology. 2007; Aug 28;69(9):904-910.
• 6. Luigi X. Cubeddu. Statin Withdrawal: Clinical Implications and Molecular Mechanisms. Pharmacotherapy. 2006;26(9):1288-1296.
• 7. C-Reactive Protein, Statins and the Risk of Vascular Events: A Better Understanding Behnood Bikdeli B.Cardiovascular Drugs and Therapy DOI: 10.1007/s10557-011-6323-7
• 8. Sever PS, Dahlöf B Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the AngloScandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet 2003;361:1149-1158.
• 9. Gurm HS, Hoogwerf B. The Heart Protection Study: High-risk patients benefit from statins regardless of LDL-C level. Clevaland Clinical Journal of Medicine. 2003;70(11): 991-997
• 10.Bilge U. Statinlere Farklı Yaklaşımlar. Turkish Family Physician 2012 Vol:2 (3);1-5