The Medicinal Use of Thyme

Abstract

Thyme, which is used widely in phytotherapy is grown commonly in Turkey. The major potent components of thyme are thymol and carvacrol. Thymol and carvacrol are observed in high rates in the varieties found in Turkey. In this review, the characteristics and usage areas of thyme are covered.

Keywords

• Phytotherapy,thymus plant,Turkey

Kekiğin Tıbbi Kullanımı

Öz

Fitoterapide geniş kullanım alanı bulan kekik Türkiye’de yaygın olarak yetişmektedir. Kekiğin major etkili bileşenleri timol ve karvakrol’dür. Kekiğin Türkiye’de bulunan çeşitlerinde timol ve karvakrol yüksek oranlardadır. Bu derlemede kekiğin özellikleri ve kullanımı ele alınmaktadır.

Anahtar Kelimeler

• Fitoterapi,kekik bitkisi,Türkiye

Kaynakça

1. 1. Uğurlu M, Üstü Y, Dağcıoğlu B.F. Fitoterapide Soğan (Bulbus Allii Cepae) ve Sarımsak (Bulbus Allii Sativi) Kullanımı. Ankara Med J 2016,16(1):119‐22.
2. 2. Üstü Y, Uğurlu M. Aloe Vera and Centella Asiatica. Ankara Med J 2017;(2):127‐31.
3. 3. Üstü Y, Uğurlu M. Fitoterapide Bitkisel Çaylar. Ankara Med J 2018;(1):137‐40.
4. 4. Knöss W. Pflanzliche Arzneimittel, Monographien als Richtschnur, https://www.pharmazeutische-zeitung.de/index.php?id=51461, Erişim tarihi: 30.05.2018.
5. 5. WHO monographs on selected medicinal plants, Volume 1, Geneva: World Health Organization Library Cataloguing in Publication Data; 1999:5‐32.
6. 6. Süzgeç Selçuk S, Eyisan S. Türkiye’deki eczanelerde bulunan bitkisel ilaçlar Marmara Pharm J 2012;16:164-80.
7. 7. European pharmacopoeia, https://www.edqm.eu/en/european‐pharmacopoeia‐ph‐eur‐9th‐ edition, Erişim tarihi: 20.01.2018.
8. 8. Zeybek U, Haksel M. Kekik (Thymus vulgaris, Thymus zygis). Türkiye’de ve Dünyada önemli Tıbbi Bitkiler ve Kullanımları. İzmir: Meta Basım; 2010:112-5.

9. 9. Meriçli F. Solunum Yolları Hastalıklarında Önemli Fitoterapötikler. Fitomed, 2010; 18(3)özel:21-2.
10. 10. Directive 2001/83/Ec of The European Parliament and of The Council Of 6 November 2001, on The Community Code Relating To Medicinal Products for Human Use Official Journal L – 311, 28/11/2004, P. 67 –128. http://www.ema.europa.eu/docs/en_GB/document_library/Regulatory_and_procedural_guideline/2009/10/WC500004481.pdf, Erişim tarihi: 23.05.2018.
11. 11. Community herbal monograph on Thymus vulgaris L. and Thymus zygis L., herba Committee on Herbal Medicinal Products (HMPC), EMA/HMPC/342332/2013, http://www.ema.europa.eu/docs/en_GB/document_library/Herbal_-_Community_herbal_monograph/2014/06/WC500167812.pdf, Erişim tarihi: 23.05.2018.
12. 12. Dauqan EMA, Abdullah A. Medicinal and Functional Values of Thyme (Thymus vulgaris L.) Herb. Journal of Applied Biology & Biotechnology 2017;5(2):17-22.
13. 13. Saleh H, Azizollah JK, Ahmadreza H, Raham A. The Application of Thymus vulgaris in traditional and modern medicine: A Review. Global Journal of Pharmacology 2015;9(3):260-6.
14. 14. Azizan A, Blevins RD. Mutagenicity and antimutagenicity testing of six chemicals associated with the pungent properties of specific spices as revealed by the Ames Salmonella microsomal assay. Arch Environ Contam Toxicol 1995;28:248–8.
15. 15. Natake M, Kanazawa K, Mizuno M et al. Herb water-extracts markedly suppress the mutagenicity of Trp-P- 2. Agricultural and Biological Chemistry 1989;53:1423–5.
16. 16. Çekin MD. Zeytinburnu Tıbbi Bitkiler Bahçesi. İstanbul: Mega Basım; 2015:18-9.
17. 17. European Medicines Agency Post-authorisation Evaluation of Medicines for Human Use, EMEA/HMPC/CHMP/CVMP/287539/2005 Rev. 1, 2009. http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/WC500003283.pdf, Erişim tarihi: 23.05.2018.
18. 18. Van Hellemont J. Fytotherapeutisch compendium, 2nd ed. Bonn: Scheltema&Holkema; 1988:571-605.
19. 19. Czygan CF. Thymian, Thymi Herba. In: Wichtl M. (ed.) Teedrogen, 2nd ed. Stuttgart: Wissenschaftliche Verlagsgesellschaft; 1989:498–500.
20. 20. Gaebler H. Gesundheit durch Heilkraeuter. Deutsche Angestellten Krankenkasse, Wittingen: Neef&Stumme Rollenoffset; 2007:2.