Nitrate in All Respects: Metabolic Pathways, Sources, and Human Health

Öz

Nitrate is a naturally occurring form of nitrogen. It exists in the air, soil, water, and plants. It is also used as a food additive in foodstuffs such as cured meats and some cheese types. Ever since the nitrate was considered as a toxic contaminant of food and water with potentially harmful effects such as methemoglobinemia and cancer. More recently, it is reported that dietary nitrate has beneficial effects for the human body. In this review, it is discussed the dietary sources of nitrate and their affecting factors, and metabolism of nitrate in the human body, as well as its benefits on human health.

Anahtar Kelimeler

• Nitrate
• nitrite
• nitric oxide
• health

Her Yönüyle Nitrat: Metabolik Yolları, Kaynakları ve İnsan Sağlığına Etkileri

Öz

Nitrat, doğal olarak meydana gelen azot formudur. Hava, toprak, su ve bitkilerde bulunur. Aynı zamanda kür edilmiş et ürünleri ve peynir gibi gıdalarda gıda katkı maddesi olarak da kullanılır. Eskiden beri, methamoglobinemia ve kanser gibi potansiyel zararlı etkilere sahip, gıda ve su için toksik kirletici olarak kabul edilmiştir. Son zamanlarda, nitratın insan vücudu için potansiyel faydaları olduğu bildirilmektedir. Bu derlemede, nitrat kaynakları ve akümülasyonu üzerine etki eden faktörler, insan vücudunda metabolizması yanı sıra sağlık üzerine yararlı etkileri tartışılmaktadır.

Anahtar Kelimeler

• Nitrat
• nitrit
• nitrik oksit
• sağlık

Kaynakça

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