Vulva cancer constitutes 4-5% of all genital cancers and 1% of gynecological cancers. Recently, the incidence of vulvar cancer has been increasing. Significant advances in treatment and care for vulvar cancer will require new thinking and research methods about therapeutic options, especially for those with advanced disease. The purpose of this review is to describe the importance of early detection and evaluation of pre-defined post-surgical symptoms in vulvar cancer. In addition, the use of evidence-relieving interventions in vulvar cancer is to summarize the present for nursing care. It is to emphasize research on the biology of vulvar cancer and facilitate the development of better strategies for patient management.
1. DeSantis, C.E., Siegal, R., Ma, J., Zou, Z., & Jemal, A. (2018). Cancer treatment and survivorship statistics. American Cancer Society. CA Cancer J Clinic, 64, 252–27.
2. Taşkın, L. (ed.) (2016). Doğum ve Kadın Sağlığı Hemşireliği. Sistem Ofset Yayıncılık, Ankara.
3. Judson, P.L., Habermann, E.B., Baxter, N.N., Durham, S.B., & Virnig, B.A. (2006). Trends in the incidence of invasive and in situ vulvar carcinoma. Obstet Gynecol, 107(5), 1018e22
4. Zweizig, S., Korets, S., & Cain, J.M. (2014). Key concepts in management of vulvar cancer. Best Pract Res Clin Obstet Gynaecol, 28, 959-966.
5. Siegel R.L., Miller K.D., & Jemal A. (2017). Cancer Statistics. CA Cancer J Clin, 67:7-30.
6. Tan, A., Bieber, A.K., Stein, JA., & Pomeranz, M.K. (2019). Diagnosis and management of vulvar cancer: A review. Journal of the American Academy of Dermatology. doi:10.1016/j.jaad.2019.07.055
7. National Cancer Institute-Surveillance, Epidemiology and End Results. (2016). Cancer Stat Facts: Vulvar Cancer. https://seer.cancer.gov/statfacts/html/ovary.html. Erişim: 30.10.2019.
8. Hampl, M., Deckers-Figiel, S., Hampl, J.A., Rein, D., & Bender, H.G. (2008). New aspects of vulvar cancer: changes in localization and age of onset. Gynecol Oncol, 109(3), 340e5.
9. Shindo, M., Ueda, Y., Kimura, T., & Matsuo, K. (2017). Diagnosis and management of vulvar cancer, in: D. Shoupe (Ed.), Handbook of Gynecology, 1st edit, New York. pp. 789–806.
10. Francis, J.A., Eiriksson, L., Dean, E., Sebastianelli, A., Bahoric, B., & Salvador, S.(2019). Management of squamous cell cancer of the vulva. Journal of Obstetrics and Gynaecology Canada, 41(1), 102-115.
11. Van der Zee, A.G.J., Oonk, MH., De Hullu, J.A., Ansink, AC., Vergote, I., & Verheijen, RH. (2008). Sentinel node dissection is safe in the treatment of early-stage vulvar cancer. J Clin Oncol Off J Am Soc Clin Oncol, 26(6), 884e91.
12. Reade, C.J., Eiriksson, L.R., & Mackay, H. (2014). Systemic chemotherapy in squamous cell carcinoma of the vulva: Current status and future directions. Gynecol Oncol, 132, 780-789.
13. Covens, A., Vella, E.T., Kennedy, E.B., Reade, C.J., Jimenez, W., & Le, T. (2015). Sentinel lymph node biopsy in vulvar cancer: Systematic review, meta-analysis and
guideline recommendations. Gynecol Oncol, 137, 351-361.
14. Moore, D.H., Koh, W.J., Mc Guire, W.P., & Wilkinson, E.J. (2009). Chapter 20: vulva. In: Barakat, R.R., Markman, M., Randall, M.E., editors. Principles and Practice of
Gynecologic Oncology. Baltimore: Lippincott Williams & Wilkins;p. 555–90.
15. Kobleder, A., Raphaelis, S., Glaus, A., Fliedner, M., Mueller, M.D., Gafner, D., et al. (2016). Recommendations for symptom management in women with vulvar neoplasms
after surgical treatment: An evidence-based guideline. European Journal of Oncology Nursing, 25, 68–76. doi:10.1016/j.ejon.2016.10.003
16. Senn, B., Mueller, M.D., Hasenburg, A., Blankenstein, T., Kammermann, B., Hartmann, A., et al. (2012). Development of a postsurgical patient-reported outcome instrument
for women with vulvar neoplasia. Oncol. Nurs. 39 (6), E489eE498. http://dx.doi.org/10.1188/ 12.ONF.E489-E498.
17. Belhadj, H., Berek, J., Bermudez, A., Bhatla, N., Denny, L., Fujiwara, K., et al. (2014). FIGO staging for carcinoma of the vulva, cervix, and corpus uteri. Int. J. Gynaecol.
obstet. 125 (2), 97e98. http:// dx.doi.org/10.1016/j.ijgo.2014.02.003
18. Sheldon, L.K., Swanson, S., Dolce, A., Marsh, K., & Summers, J. (2008). Putting evidence into practice: evidence-based interventions for anxiety. Clin. J. Oncol. Nurs. 12
(5), 789e797. http://dx.doi.org/10.1188/08.CJON.789-797
19. Herrero, R., Hildesheim, A., Rodriguez, A.C, Wacholder, S., Bratti, C., Solomon, D., et al. (2008). Rationale and design of a community-based double-blind randomized
clinical trial of an HPV 16 and 18 vaccine in Guanacaste, Costa Rica Vaccine, 26, 4795-4808
20. Beatty, LJ., Koczwar,a B., Rice, J., & Wade, TD. (2010). A randomised controlled trial to evaluate the effects of a self-help workbook intervention on distress, coping and
quality of life after breast cancer diagnosis. Med. J. 193 (5), S68eS73.
21. Zhang, N., Fielding, R., Soong, I., Chan, KK., Tsang, J., Lee, V. et al. (2006). Illness perceptions among cancer survivors. Supportive Care in Cancer, 24(3), 1295-304.
22. Küçükkaya, B., & Erçel, Ö. (2019). Jinekolojik kanserli hastalarda hastalık algısının öz-bakım gücüne etkisi. Ege üniversitesi hemşirelik fakültesi dergisi. 35(3), 137-145.
23. Süt, H.K. (2017). Jinekolojik Cerrahi Operasyon Öncesi Hastaların Hastalık Algıları Üzerine Etkili Faktörler. Bakırköy Tıp Dergisi, 13, 83-90.
24. Green, M.S., Naumann, RW., Elliot, M., Hall, J.B., Higgins, R.V., & Grigsby. J.H. (2000). Sexual dysfunction following vulvectomy. Gynecol Oncol, 77, 73-7.
25. Thuesen, B., Andreasson, B., & Bock, J.E. (1992). Sexual function and somatopsychic reactions after local excision of vulvar intra-epithelial neoplasia. Acta Obstet Gynecol
Scand, 71, 126-8.
26. Jensen, P.T. (2007). Gynaecological cancer and sexual functioning: Does treatment modality have an impact? Sexologies, 16(4), 279–285. doi:10.1016/j.sexol.2007.06.010
27. Chow, K.M., Chan, C.W.H., & Chan, J.C.Y. (2012). Effects of psychoeducational interventions on sexual functioning, quality of life and psychological outcomes in patients
with gynaecologcal cancer. JBL libraryof systematic reviews. 10(58), 4077-4164.
28. Southard, N.Z., & Keller, J. (2009). The importance of assessing sexuality: A patient perspective. Clin J Oncol Nurs, 13(2), 213-7.
29. Köse, F., & Karabük, E. (2017). Surgical management of vulvar carcinoma. Turkiye Klinikleri J Gynecol Obst-Special Topics, 10(2), 203-9.
30. Şirin, A., Kavlak, O. (ed.) (2015). Kadın Sağlığı, Nobel Yayıncılık, İstanbul.
31. Uzun, O., Ucuzal, M., & İnan, G. (2011). Post-Discharge Learning Needs of General Surgery Patients. Pak J Med Sci, 27(3), 634-637.
32. Beck, S. L., Brant, J. M., Donohue, R., Smith, E. M. L., Towsley, G. L., Berry, P. H., et al. (2016). Oncology nursing certification: relation to nurses' knowledge and attitudes
about pain, patient-reported pain care quality, and pain outcomes. Oncol Nurs Forum, 43 (1), 67-76.
Vulva Kanseri ve Vulvektomi Sonrası Hemşirelik Yaklaşımları
Vulva kanseri tüm genital kanserlerin %4-5’ini, jinekolojik kanserlerin de %1’ini oluşturur. Son yıllarda vulva kanseri insidansı artış göstermektedir. Vulva kanseri için tedavi ve bakımdaki önemli gelişmeler, özellikle ileri evre hastalığı olanlar için terapötik seçenekler hakkında yeni düşünme ve araştırma yöntemleri gerektirecektir. Bu derlemenin amacı, vulva kanserinde önceden tanımlanmış cerrahi sonrası semptomların erken saptanmasını ve değerlendirilmesinin önemi anlatılmaktadır. Ayrıca vulva kanserinde kanıta dayalı semptom giderici müdahalelerin kullanımıyla hemşirelik bakımına yönelik mevcut kanıtları özetlemektir. Vulva kanserinin biyolojisi hakkındaki en son araştırmaları vurgulamak ve hasta yönetimi için daha iyi stratejilerin geliştirilmesini kolaylaştırmaktır.
1. DeSantis, C.E., Siegal, R., Ma, J., Zou, Z., & Jemal, A. (2018). Cancer treatment and survivorship statistics. American Cancer Society. CA Cancer J Clinic, 64, 252–27.
2. Taşkın, L. (ed.) (2016). Doğum ve Kadın Sağlığı Hemşireliği. Sistem Ofset Yayıncılık, Ankara.
3. Judson, P.L., Habermann, E.B., Baxter, N.N., Durham, S.B., & Virnig, B.A. (2006). Trends in the incidence of invasive and in situ vulvar carcinoma. Obstet Gynecol, 107(5), 1018e22
4. Zweizig, S., Korets, S., & Cain, J.M. (2014). Key concepts in management of vulvar cancer. Best Pract Res Clin Obstet Gynaecol, 28, 959-966.
5. Siegel R.L., Miller K.D., & Jemal A. (2017). Cancer Statistics. CA Cancer J Clin, 67:7-30.
6. Tan, A., Bieber, A.K., Stein, JA., & Pomeranz, M.K. (2019). Diagnosis and management of vulvar cancer: A review. Journal of the American Academy of Dermatology. doi:10.1016/j.jaad.2019.07.055
7. National Cancer Institute-Surveillance, Epidemiology and End Results. (2016). Cancer Stat Facts: Vulvar Cancer. https://seer.cancer.gov/statfacts/html/ovary.html. Erişim: 30.10.2019.
8. Hampl, M., Deckers-Figiel, S., Hampl, J.A., Rein, D., & Bender, H.G. (2008). New aspects of vulvar cancer: changes in localization and age of onset. Gynecol Oncol, 109(3), 340e5.
9. Shindo, M., Ueda, Y., Kimura, T., & Matsuo, K. (2017). Diagnosis and management of vulvar cancer, in: D. Shoupe (Ed.), Handbook of Gynecology, 1st edit, New York. pp. 789–806.
10. Francis, J.A., Eiriksson, L., Dean, E., Sebastianelli, A., Bahoric, B., & Salvador, S.(2019). Management of squamous cell cancer of the vulva. Journal of Obstetrics and Gynaecology Canada, 41(1), 102-115.
11. Van der Zee, A.G.J., Oonk, MH., De Hullu, J.A., Ansink, AC., Vergote, I., & Verheijen, RH. (2008). Sentinel node dissection is safe in the treatment of early-stage vulvar cancer. J Clin Oncol Off J Am Soc Clin Oncol, 26(6), 884e91.
12. Reade, C.J., Eiriksson, L.R., & Mackay, H. (2014). Systemic chemotherapy in squamous cell carcinoma of the vulva: Current status and future directions. Gynecol Oncol, 132, 780-789.
13. Covens, A., Vella, E.T., Kennedy, E.B., Reade, C.J., Jimenez, W., & Le, T. (2015). Sentinel lymph node biopsy in vulvar cancer: Systematic review, meta-analysis and
guideline recommendations. Gynecol Oncol, 137, 351-361.
14. Moore, D.H., Koh, W.J., Mc Guire, W.P., & Wilkinson, E.J. (2009). Chapter 20: vulva. In: Barakat, R.R., Markman, M., Randall, M.E., editors. Principles and Practice of
Gynecologic Oncology. Baltimore: Lippincott Williams & Wilkins;p. 555–90.
15. Kobleder, A., Raphaelis, S., Glaus, A., Fliedner, M., Mueller, M.D., Gafner, D., et al. (2016). Recommendations for symptom management in women with vulvar neoplasms
after surgical treatment: An evidence-based guideline. European Journal of Oncology Nursing, 25, 68–76. doi:10.1016/j.ejon.2016.10.003
16. Senn, B., Mueller, M.D., Hasenburg, A., Blankenstein, T., Kammermann, B., Hartmann, A., et al. (2012). Development of a postsurgical patient-reported outcome instrument
for women with vulvar neoplasia. Oncol. Nurs. 39 (6), E489eE498. http://dx.doi.org/10.1188/ 12.ONF.E489-E498.
17. Belhadj, H., Berek, J., Bermudez, A., Bhatla, N., Denny, L., Fujiwara, K., et al. (2014). FIGO staging for carcinoma of the vulva, cervix, and corpus uteri. Int. J. Gynaecol.
obstet. 125 (2), 97e98. http:// dx.doi.org/10.1016/j.ijgo.2014.02.003
18. Sheldon, L.K., Swanson, S., Dolce, A., Marsh, K., & Summers, J. (2008). Putting evidence into practice: evidence-based interventions for anxiety. Clin. J. Oncol. Nurs. 12
(5), 789e797. http://dx.doi.org/10.1188/08.CJON.789-797
19. Herrero, R., Hildesheim, A., Rodriguez, A.C, Wacholder, S., Bratti, C., Solomon, D., et al. (2008). Rationale and design of a community-based double-blind randomized
clinical trial of an HPV 16 and 18 vaccine in Guanacaste, Costa Rica Vaccine, 26, 4795-4808
20. Beatty, LJ., Koczwar,a B., Rice, J., & Wade, TD. (2010). A randomised controlled trial to evaluate the effects of a self-help workbook intervention on distress, coping and
quality of life after breast cancer diagnosis. Med. J. 193 (5), S68eS73.
21. Zhang, N., Fielding, R., Soong, I., Chan, KK., Tsang, J., Lee, V. et al. (2006). Illness perceptions among cancer survivors. Supportive Care in Cancer, 24(3), 1295-304.
22. Küçükkaya, B., & Erçel, Ö. (2019). Jinekolojik kanserli hastalarda hastalık algısının öz-bakım gücüne etkisi. Ege üniversitesi hemşirelik fakültesi dergisi. 35(3), 137-145.
23. Süt, H.K. (2017). Jinekolojik Cerrahi Operasyon Öncesi Hastaların Hastalık Algıları Üzerine Etkili Faktörler. Bakırköy Tıp Dergisi, 13, 83-90.
24. Green, M.S., Naumann, RW., Elliot, M., Hall, J.B., Higgins, R.V., & Grigsby. J.H. (2000). Sexual dysfunction following vulvectomy. Gynecol Oncol, 77, 73-7.
25. Thuesen, B., Andreasson, B., & Bock, J.E. (1992). Sexual function and somatopsychic reactions after local excision of vulvar intra-epithelial neoplasia. Acta Obstet Gynecol
Scand, 71, 126-8.
26. Jensen, P.T. (2007). Gynaecological cancer and sexual functioning: Does treatment modality have an impact? Sexologies, 16(4), 279–285. doi:10.1016/j.sexol.2007.06.010
27. Chow, K.M., Chan, C.W.H., & Chan, J.C.Y. (2012). Effects of psychoeducational interventions on sexual functioning, quality of life and psychological outcomes in patients
with gynaecologcal cancer. JBL libraryof systematic reviews. 10(58), 4077-4164.
28. Southard, N.Z., & Keller, J. (2009). The importance of assessing sexuality: A patient perspective. Clin J Oncol Nurs, 13(2), 213-7.
29. Köse, F., & Karabük, E. (2017). Surgical management of vulvar carcinoma. Turkiye Klinikleri J Gynecol Obst-Special Topics, 10(2), 203-9.
30. Şirin, A., Kavlak, O. (ed.) (2015). Kadın Sağlığı, Nobel Yayıncılık, İstanbul.
31. Uzun, O., Ucuzal, M., & İnan, G. (2011). Post-Discharge Learning Needs of General Surgery Patients. Pak J Med Sci, 27(3), 634-637.
32. Beck, S. L., Brant, J. M., Donohue, R., Smith, E. M. L., Towsley, G. L., Berry, P. H., et al. (2016). Oncology nursing certification: relation to nurses' knowledge and attitudes
about pain, patient-reported pain care quality, and pain outcomes. Oncol Nurs Forum, 43 (1), 67-76.
Keskin, H. G., & Tahta, T. (2021). Vulva Kanseri ve Vulvektomi Sonrası Hemşirelik Yaklaşımları. Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi, 5(1), 115-121. https://doi.org/10.46237/amusbfd.725542