Current Approach to Ketogenic Medical Nutrition Treatment with Adult Applications in Refractory Epilepsy

Yıl 2021, Cilt: 5 Sayı: 2, 431 - 441, 29.05.2021

Nurdan Şener , Gamze Akbulut

https://doi.org/10.46237/amusbfd.767163

Cited By: 1

Öz

Since epilepsy can occur at any age, has a long treatment period and requires follow up, it greatly affects the quality of life. It was first described as a ‘brain disorder’ by Hippocrates. In the treatment of epilepsy; drug therapy, surgical treatment, and ketogenic medical nutrition therapy can be used. Hunger is accepted as an epilepsy treatment since the Hippocrates period. High-fat, low-carbohydrate ketogenic medical nutrition treatment mimic the metabolic state of hunger and ensures that fat is used as the main source of energy in the body. The enzyme that is metabolises ketone bodies is more in infants and children in terms of quantity, and it decreases with the aging process. Before starting ketogenic medical nutrition therapy, detailed food consumption record from the individual, evaluation of growth in infants and children by considering various parameters, obesity, malnutrition and so on should be obtained as important to determine the situations and calculate the appropriate daily energy requirement accordingly. In this review, ketogenic nutrition treatment is discussed with the current approach and with the examples of ketogenic medical nutrition treatment calculation.

Anahtar Kelimeler

Epilepsy, Ketogenic medical nutrition therapy, Ketone bodies

Dirençli Epilepside Erişkin Uygulamaları ile Birlikte Ketojenik Tıbbi Beslenme Tedavisine Güncel Yaklaşım

Öz

Epilepsi her yaşta ortaya çıkabilen, tedavi süresi uzun olan ve izlem gerektiren bir hastalık olmakla beraber yaşam kalitesini büyük ölçüde etkilemektedir. İlk kez Hipokrat tarafından “beyin hastalığı” olarak ifade edilmiştir. Epilepsinin tedavisinde, ilaç tedavisi, cerrahi tedavi ve ketojenik tıbbi beslenme tedavisi kullanılabilmektedir. Açlık, Hipokrat döneminden itibaren epilepsinin tedavisi olarak kabul edilmiştir. Ketojenik tıbbi beslenme tedavisi, yüksek yağ ve düşük karbonhidrat içeriği ile açlığın metabolik durumunu taklit ederek yağların vücutta ilk enerji kaynağı olarak kullanılmasını sağlamaktadır. Keton cisimciklerini metabolize eden enzim, bebeklerde ve çocuklarda daha fazla bulunmaktadır ve artan yaş ile azalmaktadır. Bu nedenle bebeklerde ve küçük yaştaki çocuklarda daha etkin bir tıbbi beslenme tedavisidir. Ketojenik tıbbi beslenme tedavisine başlanmadan önce, bireyden ayrıntılı besin tüketim kaydının alınması, bebeklerde ve çocuklarda çeşitli parametreler göz önünde bulundurularak büyümenin değerlendirilmesi, obezite, malnütrisyon vb. durumların saptanması ve bu doğrultuda uygun günlük enerji gereksinimin hesaplanması önemlidir. Bu derlemede ketojenik tıbbi beslenme tedavisine güncel yaklaşımla birlikte ketojenik tıbbi beslenme tedavisi hesaplama örneklerine de yer verilmiştir.

Anahtar Kelimeler

Epilepsi, keton cisimcikleri, ketojenik tıbbi beslenme tedavisi

Kaynakça

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