The Effect of Mediterranean Diet on Prevention and Treatment of Breast Cancer

Yıl 2021, Cilt: 5 Sayı: 2, 442 - 454, 29.05.2021

Burcu Deniz Güneş Nilüfer Acar Tek

https://doi.org/10.46237/amusbfd.879374

Öz

Breast cancer is one of the most common and fatal carcinomas worldwide and poses a serious threat to women's health. Lifestyle factors such as malnutrition, obesity, and lack of physical activity are known to be associated with a higher risk of breast cancer. The Mediterranean diet is considered one of the healthiest eating patterns worldwide, mainly due to its rich content of antioxidants and anti-inflammatory foods. It has been suggested that the combination of dietary components plays a common role in reducing inflammation and oxidative stress, thereby preventing the progression of various malignancies, including cardiovascular diseases and cancer. Considering its protective effects in reducing the oxidative and inflammatory processes of cells and preventing deoxyribo nucleic acid damage, cell proliferation and survival, angiogenesis, inflammation and metastases, the Mediterranean diet is thought to be an effective method in preventing breast cancer and in the treatment of breast cancer. This review is written to examine the potential effects of the Mediterranean diet on breast cancer prevention and breast cancer treatment.

Anahtar Kelimeler

Breast cancer, Mediterranean diet, Bioactive compounds

Meme Kanserinden Korunmada ve Meme Kanseri Tedavisinde Akdeniz Diyetinin Etkisi

Öz

Meme kanseri, dünya çapında en yaygın ve ölümcül karsinomlardan biridir ve kadın sağlığı için ciddi bir tehdit oluşturmaktadır. Kötü beslenme, obezite, fiziksel aktivite eksikliği gibi yaşam tarzı faktörlerinin daha yüksek meme kanseri riski ile ilişkili olduğu bilinmektedir. Akdeniz diyeti, temel olarak antioksidanlar ve antiinflamatuvar besinler açısından zengin içeriğe sahip olması nedeniyle dünya çapında en sağlıklı beslenme modellerinden biri olarak kabul edilmektedir. Diyet bileşenlerinin kombinasyonunun; inflamasyonu ve oksidatif stresi azaltmada ortak bir rol oynadığı, dolayısıyla kardiyovasküler hastalıklar ve kanser dahil olmak üzere çeşitli malignitelerin ilerlemesine engel olduğu öne sürülmüştür. Hücrelerin oksidatif ve inflamatuvar süreçlerini azaltmada ve deoksiribo nükleik asit hasarlarını, hücre proliferasyonunu ve hayatta kalmalarını, anjiyogenezleri, inflamasyonu ve metastazları önlemedeki koruyucu etkileri göz önüne alındığında, Akdeniz diyetinin meme kanserinden korunmada ve meme kanseri tedavisinde etkili bir yöntem olabileceği düşünülmektedir. Bu derleme, Akdeniz diyetinin meme kanserinden korunmadaki ve meme kanseri tedavisindeki potansiyel etkilerinin incelenmesi amacıyla yazılmıştır.

Anahtar Kelimeler

Meme kanseri, Akdeniz diyeti, biyoaktif bileşikler

Kaynakça

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