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Kalori Kısıtlaması ve Sağlığa Faydalı Etkilerine Bir Bakış

Yıl 2022, Cilt: 6 Sayı: 3, 544 - 553, 30.09.2022
https://doi.org/10.46237/amusbfd.1082140

Öz

Kalori kısıtlaması yıllardır araştırmalara ve çalışmalara konu olmuştur. Kalori kısıtlaması geniş bir tanım olması ile beraber kısıtlamanın uygulanma şekli, zamanı, miktarı ve hangi durumlarda yapılacağı oldukça önemlidir. Kısıtlama yapılırken karbonhidrat, yağ ve protein dengeleri iyi değerlendirilmelidir. Ancak bu kısıtlama, yetersiz beslenmeye sebep olmaksızın uygun koşullarda yapıldığı zaman çeşitli olumlu etkileri göstermektedir. Kalori kısıtlaması ile serbest radikallerin üretimi ve sebep oldukları oksidatif stres azaltılır. Yaygın olarak görülen kronik hastalıklarda uygulanan medikal tedavilere ek; alternatif bir yöntem olarak hastalığa özgü gerekli kalori kısıtlamaları ile yaşamsal fonksiyonlarda düzelmelerin meydana geldiği görülmektedir. Sağlığın yaşam boyu sürdürülmesi ancak dengeli beslenme, düzenli ve sürekli egzersiz programı ile birlikte mümkündür. Beslenme hayatın her döneminde dikkat edilmesi gereken bir konudur. Uzun ve sağlıklı bir yaşam sürmede en önemli kilit noktalardan birinin beslenme olduğu unutulmamalıdır. Bu nedenle bu derlemenin amacı; güncelliğini korumakta olan ve araştırmaları süren bir konu olarak kalori kısıtlamasının bazı faydalı etkilerine yapılan çalışmalardan örnekler ile değinerek dikkat çekmektir.

Kaynakça

  • 1. Hagopian, K., Ramsey, J. J., & Weindruch, R. (2005). Fructose metabolizing enzymes from mouse liver: influence of age and caloric restriction. Biochimica et Biophysica Acta (BBA)-General Subjects, 1721(1-3), 37-43.
  • 2. McCay, C. M., Crowell, M. F., & Maynard, L. A. (1935). The effect of retarded growth upon the length of life span and upon the ultimate body size: one figure. The Journal of Nutrition, 10(1), 63-79.
  • 3. Mohammadi, M., Ghaznavi, R., Keyhanmanesh, R., Sadeghipour, H. R., Naderi, R., & Mohammadi, H. (2014). Caloric restriction prevents lead-induced oxidative stress and inflammation in rat liver. The Scientific World Journal, 2014, 821524.
  • 4. Heilbronn, L. K., De Jonge, L., Frisard, M. I., DeLany, J. P., Larson-Meyer, D. E., Rood, J., et al. (2006). Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial. Jama, 295(13), 1539-1548.
  • 5. Nicoll, R., & Henein, M. Y. (2018). Caloric restriction and its effect on blood pressure, heart rate variability and arterial stiffness and dilatation: a review of the evidence. International Journal of Molecular Sciences, 19(3), 751.
  • 6. Demetrius, L. (2005). Of mice and men: when it comes to studying ageing and the means to slow it down, mice are not just small humans. EMBO reports, 6(S1), S39-S44.
  • 7. Dal-Pan, A., Pifferi, F., Marchal, J., Picq, J. L., Aujard, F., & Restrikal Consortium. (2011). Cognitive performances are selectively enhanced during chronic caloric restriction or resveratrol supplementation in a primate. PLoS ONE, 6(1), e16581.
  • 8. Maalouf, M., Rho, J. M., & Mattson, M. P. (2009). The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies. Brain Research Reviews, 59(2), 293-315.
  • 9. Arslan-Ergul, A., Ozdemir, A. T., & Adams, M. M. (2013). Aging, neurogenesis, and caloric restriction in different model organisms. Aging and Disease, 4(4), 221.
  • 10. Fontana, L. (2009). The scientific basis of caloric restriction leading to longer life. Current Opinion in Gastroenterology, 25(2), 144-150.
  • 11. Yin, Z., Raj, D. D., Schaafsma, W., Van der Heijden, R. A., Kooistra, S. M., Reijne, A. C., et al. (2018). Low-fat diet with caloric restriction reduces white matter microglia activation during aging. Frontiers in molecular neuroscience, 11, 65.
  • 12. Doğuç, D. K., Yılmaz, N., Vural, H., & Kara, Y. (2013). Sıçanlarda kalori kısıtlamasının lipid peroksidasyonu ve antioksidan enzimlere etkisi. Sakarya Tıp Dergisi, 3(1), 19-24.
  • 13. Li, J., Zhang, C. X., Liu, Y. M., Chen, K. L., & Chen, G. (2017). A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction. Oncotarget, 8(39), 65717.
  • 14. Zhang, Y., Liu, C., Zhao, Y., Zhang, X., Li, B., & Cui, R. (2015). The effects of calorie restriction in depression and potential mechanisms. Current Neuropharmacology, 13(4), 536-542.
  • 15. Manchishi, S. M., Cui, R. J., Zou, X. H., Cheng, Z. Q., & Li, B. J. (2018). Effect of caloric restriction on depression. Journal of Cellular and Molecular Medicine, 22(5), 2528-2535.
  • 16. Burkhalter, J., Fiumelli, H., Allaman, I., Chatton, J. Y., & Martin, J. L. (2003). Brain-derived neurotrophic factor stimulates energy metabolism in developing cortical neurons. Journal of Neuroscience, 23(23), 8212- 8220.
  • 17. Michalsen, A., Weidenhammer, W., Melchart, D., Langhorst, J., Saha, J., & Dobos, G. (2002). Kurzzeitiges therapeutisches Fasten in der Behandlung von chronischen Schmerz-und Erschöpfungssyndromen– Verträglichkeit und Nebenwirkungen mit und ohne begleitende Mineralstoffergänzung. Complementary Medicine Research, 9(4), 221-227. (Michalsen, A., Weidenhammer, W., Melchart, D., Langhorst, J., Saha, J., & Dobos, G. (2002). Short-term therapeutic fasting in the treatment of chronic pain and fatigue syndromes - tolerability and side effects with and without concomitant mineral supplements. Complementary Medicine Research, 9(4), 221-227.)
  • 18. Kartal K. (2019). Düşük kalorili diyet tedavisi uygulanan hafif şişman/şişman bireylerin depresyon derecesi ve yeme davranışının değerlendirilmesi. (Yayımlanmamış Yüksek Lisans Tezi). Hasan Kalyoncu Üniversitesi Sağlık Bilimleri Enstitüsü, GAZİANTEP
  • 19. Ungvari, Z., Parrado-Fernandez, C., Csiszar, A., & de Cabo, R. (2008). Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging. Circulation Research, 102(5), 519-528.
  • 20. Blumenthal, J. A., Babyak, M. A., Hinderliter, A., Watkins, L. L., Craighead, L., Lin, P. H., et al. (2010). Effects of the DASH diet alone and in combination with exercise and weight loss on blood pressure and cardiovascular biomarkers in men and women with high blood pressure: the ENCORE study. Archives of Internal Medicine, 170(2), 126-135.
  • 21. Çakıcı, Ö., & Kurtoğlu, F. (2017). Biochemical values of male mice fed with restricted calorie diet. Eurasian Journal of Veterinary Sciences, 33(3), 138-147.
  • 22. Macit, Ç. (2015). Yaşlanmada egzersizin ve kalori kısıtlamasının kardiyovasküler hemodinamiye, erektil fonksiyona ve antioksidan sistemlere etkisi. İstanbul, Türkiye.
  • 23. Barquissau, V., Léger, B., Beuzelin, D., Martins, F., Amri, E. Z., Pisani, D. F., et al. (2018). Caloric restriction and diet-induced weight loss do not induce browning of human subcutaneous white adipose tissue in women and men with obesity. Cell Reports, 22(4), 1079-1089.
  • 24. van Eyk, H. J., van Schinkel, L. D., Kantae, V., Dronkers, C. E., Westenberg, J. J., de Roos, A., et al. (2018). Caloric restriction lowers endocannabinoid tonus and improves cardiac function in type 2 diabetes. Nutrition & Diabetes, 8(1), 6.
  • 25. Bianchi, V. E. (2020). Impact of nutrition on cardiovascular function. Current Problems in Cardiology, 45(1), 100391.
  • 26. Ott, B., Skurk, T., Hastreiter, L., Lagkouvardos, I., Fischer, S., Büttner, J., et al. (2017). Effect of caloric restriction on gut permeability, inflammation markers, and fecal microbiota in obese women. Scientific Reports, 7(1), 1-10.
  • 27. Aksungar, F. B., Sarikaya, M., Coskun, A., Serteser, M., & Unsal, I. (2017). Comparison of intermittent fasting versus caloric restriction in obese subjects: A two year follow-up. The Journal of Nutrition, Health & Aging, 21(6), 681.
  • 28. Ibarra-Reynoso, L. D. R., López-Lemus, H. L., Garay-Sevilla, M. E., & Malacara, J. M. (2017). Effect of restriction of foods with high fructose corn syrup content on metabolic ındices and fatty liver in obese children. Obesity Facts, 10(4), 332-340.
  • 29. Ruiz-Hurtado, G., García-Prieto, C. F., Pulido-Olmo, H., Velasco-Martín, J. P., Villa-Valverde, P., Fernández-Valle, M. E., et al. (2017). Mild and short-term caloric restriction prevents obesity-induced cardiomyopathy in young Zucker rats without changing in metabolites and fatty acids cardiac profile. Frontiers in Physiology, 8, 42.
  • 30. Karan, M. A., & Tufan, F. (2010). Yaşlanma mekanizmaları. Ege Tıp Dergisi, 49(3), 11-18.

A Review of Calorie Restriction and Beneficial Health Effects

Yıl 2022, Cilt: 6 Sayı: 3, 544 - 553, 30.09.2022
https://doi.org/10.46237/amusbfd.1082140

Öz

Calorie restriction has been the subject of research and studies for years. Although calorie restriction is a broad definition; the way, time, amount and situations of restriction are very important. While restricting, carbohydrate, fat and protein balances should be well evaluated. However, this restriction shows various positive effects when done under suitable conditions without causing malnutrition. With calorie restriction, the production of free radicals and the oxidative stress they cause are reduced. In addition to medical treatments applied in common chronic diseases; as an alternative method, it is seen that improvements in vital functions occur with the necessary calorie restrictions specific to the disease. Maintaining health throughout life is only possible with a balanced diet, regular and continuous exercise program. Nutrition is an issue that needs attention in every period of life. It should not be forgotten that one of the most important key points in living a long and healthy life is nutrition. Therefore, the purpose of this review; is to draw attention to some beneficial effects of calorie restriction, as a topic that is still up-to-date and researches, by giving examples from studies.

Kaynakça

  • 1. Hagopian, K., Ramsey, J. J., & Weindruch, R. (2005). Fructose metabolizing enzymes from mouse liver: influence of age and caloric restriction. Biochimica et Biophysica Acta (BBA)-General Subjects, 1721(1-3), 37-43.
  • 2. McCay, C. M., Crowell, M. F., & Maynard, L. A. (1935). The effect of retarded growth upon the length of life span and upon the ultimate body size: one figure. The Journal of Nutrition, 10(1), 63-79.
  • 3. Mohammadi, M., Ghaznavi, R., Keyhanmanesh, R., Sadeghipour, H. R., Naderi, R., & Mohammadi, H. (2014). Caloric restriction prevents lead-induced oxidative stress and inflammation in rat liver. The Scientific World Journal, 2014, 821524.
  • 4. Heilbronn, L. K., De Jonge, L., Frisard, M. I., DeLany, J. P., Larson-Meyer, D. E., Rood, J., et al. (2006). Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial. Jama, 295(13), 1539-1548.
  • 5. Nicoll, R., & Henein, M. Y. (2018). Caloric restriction and its effect on blood pressure, heart rate variability and arterial stiffness and dilatation: a review of the evidence. International Journal of Molecular Sciences, 19(3), 751.
  • 6. Demetrius, L. (2005). Of mice and men: when it comes to studying ageing and the means to slow it down, mice are not just small humans. EMBO reports, 6(S1), S39-S44.
  • 7. Dal-Pan, A., Pifferi, F., Marchal, J., Picq, J. L., Aujard, F., & Restrikal Consortium. (2011). Cognitive performances are selectively enhanced during chronic caloric restriction or resveratrol supplementation in a primate. PLoS ONE, 6(1), e16581.
  • 8. Maalouf, M., Rho, J. M., & Mattson, M. P. (2009). The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies. Brain Research Reviews, 59(2), 293-315.
  • 9. Arslan-Ergul, A., Ozdemir, A. T., & Adams, M. M. (2013). Aging, neurogenesis, and caloric restriction in different model organisms. Aging and Disease, 4(4), 221.
  • 10. Fontana, L. (2009). The scientific basis of caloric restriction leading to longer life. Current Opinion in Gastroenterology, 25(2), 144-150.
  • 11. Yin, Z., Raj, D. D., Schaafsma, W., Van der Heijden, R. A., Kooistra, S. M., Reijne, A. C., et al. (2018). Low-fat diet with caloric restriction reduces white matter microglia activation during aging. Frontiers in molecular neuroscience, 11, 65.
  • 12. Doğuç, D. K., Yılmaz, N., Vural, H., & Kara, Y. (2013). Sıçanlarda kalori kısıtlamasının lipid peroksidasyonu ve antioksidan enzimlere etkisi. Sakarya Tıp Dergisi, 3(1), 19-24.
  • 13. Li, J., Zhang, C. X., Liu, Y. M., Chen, K. L., & Chen, G. (2017). A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction. Oncotarget, 8(39), 65717.
  • 14. Zhang, Y., Liu, C., Zhao, Y., Zhang, X., Li, B., & Cui, R. (2015). The effects of calorie restriction in depression and potential mechanisms. Current Neuropharmacology, 13(4), 536-542.
  • 15. Manchishi, S. M., Cui, R. J., Zou, X. H., Cheng, Z. Q., & Li, B. J. (2018). Effect of caloric restriction on depression. Journal of Cellular and Molecular Medicine, 22(5), 2528-2535.
  • 16. Burkhalter, J., Fiumelli, H., Allaman, I., Chatton, J. Y., & Martin, J. L. (2003). Brain-derived neurotrophic factor stimulates energy metabolism in developing cortical neurons. Journal of Neuroscience, 23(23), 8212- 8220.
  • 17. Michalsen, A., Weidenhammer, W., Melchart, D., Langhorst, J., Saha, J., & Dobos, G. (2002). Kurzzeitiges therapeutisches Fasten in der Behandlung von chronischen Schmerz-und Erschöpfungssyndromen– Verträglichkeit und Nebenwirkungen mit und ohne begleitende Mineralstoffergänzung. Complementary Medicine Research, 9(4), 221-227. (Michalsen, A., Weidenhammer, W., Melchart, D., Langhorst, J., Saha, J., & Dobos, G. (2002). Short-term therapeutic fasting in the treatment of chronic pain and fatigue syndromes - tolerability and side effects with and without concomitant mineral supplements. Complementary Medicine Research, 9(4), 221-227.)
  • 18. Kartal K. (2019). Düşük kalorili diyet tedavisi uygulanan hafif şişman/şişman bireylerin depresyon derecesi ve yeme davranışının değerlendirilmesi. (Yayımlanmamış Yüksek Lisans Tezi). Hasan Kalyoncu Üniversitesi Sağlık Bilimleri Enstitüsü, GAZİANTEP
  • 19. Ungvari, Z., Parrado-Fernandez, C., Csiszar, A., & de Cabo, R. (2008). Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging. Circulation Research, 102(5), 519-528.
  • 20. Blumenthal, J. A., Babyak, M. A., Hinderliter, A., Watkins, L. L., Craighead, L., Lin, P. H., et al. (2010). Effects of the DASH diet alone and in combination with exercise and weight loss on blood pressure and cardiovascular biomarkers in men and women with high blood pressure: the ENCORE study. Archives of Internal Medicine, 170(2), 126-135.
  • 21. Çakıcı, Ö., & Kurtoğlu, F. (2017). Biochemical values of male mice fed with restricted calorie diet. Eurasian Journal of Veterinary Sciences, 33(3), 138-147.
  • 22. Macit, Ç. (2015). Yaşlanmada egzersizin ve kalori kısıtlamasının kardiyovasküler hemodinamiye, erektil fonksiyona ve antioksidan sistemlere etkisi. İstanbul, Türkiye.
  • 23. Barquissau, V., Léger, B., Beuzelin, D., Martins, F., Amri, E. Z., Pisani, D. F., et al. (2018). Caloric restriction and diet-induced weight loss do not induce browning of human subcutaneous white adipose tissue in women and men with obesity. Cell Reports, 22(4), 1079-1089.
  • 24. van Eyk, H. J., van Schinkel, L. D., Kantae, V., Dronkers, C. E., Westenberg, J. J., de Roos, A., et al. (2018). Caloric restriction lowers endocannabinoid tonus and improves cardiac function in type 2 diabetes. Nutrition & Diabetes, 8(1), 6.
  • 25. Bianchi, V. E. (2020). Impact of nutrition on cardiovascular function. Current Problems in Cardiology, 45(1), 100391.
  • 26. Ott, B., Skurk, T., Hastreiter, L., Lagkouvardos, I., Fischer, S., Büttner, J., et al. (2017). Effect of caloric restriction on gut permeability, inflammation markers, and fecal microbiota in obese women. Scientific Reports, 7(1), 1-10.
  • 27. Aksungar, F. B., Sarikaya, M., Coskun, A., Serteser, M., & Unsal, I. (2017). Comparison of intermittent fasting versus caloric restriction in obese subjects: A two year follow-up. The Journal of Nutrition, Health & Aging, 21(6), 681.
  • 28. Ibarra-Reynoso, L. D. R., López-Lemus, H. L., Garay-Sevilla, M. E., & Malacara, J. M. (2017). Effect of restriction of foods with high fructose corn syrup content on metabolic ındices and fatty liver in obese children. Obesity Facts, 10(4), 332-340.
  • 29. Ruiz-Hurtado, G., García-Prieto, C. F., Pulido-Olmo, H., Velasco-Martín, J. P., Villa-Valverde, P., Fernández-Valle, M. E., et al. (2017). Mild and short-term caloric restriction prevents obesity-induced cardiomyopathy in young Zucker rats without changing in metabolites and fatty acids cardiac profile. Frontiers in Physiology, 8, 42.
  • 30. Karan, M. A., & Tufan, F. (2010). Yaşlanma mekanizmaları. Ege Tıp Dergisi, 49(3), 11-18.
Toplam 30 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Derleme Makaleler
Yazarlar

Fatma Nur Armağan 0000-0003-0089-8781

Sevde Evcim 0000-0002-1616-2421

Serdal Öğüt 0000-0001-8863-7249

Yayımlanma Tarihi 30 Eylül 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 6 Sayı: 3

Kaynak Göster

APA Armağan, F. N., Evcim, S., & Öğüt, S. (2022). A Review of Calorie Restriction and Beneficial Health Effects. Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi, 6(3), 544-553. https://doi.org/10.46237/amusbfd.1082140