Olgu Sunumu
BibTex RIS Kaynak Göster

A childhood secondary headache case associated with Langerhans cell histiocytosis

Yıl 2023, , 216 - 220, 23.05.2023
https://doi.org/10.21673/anadoluklin.1239361

Öz

Neurological involvement is very rare in patients with a diagnosis of Langerhans Cell Histiocytosis (LCH). During the course of the disease, headache can also be seen in addition to systemic effects. A 6 years old girl was admitted to the hospital with only a headache without any systemic symptoms and was diagnosed with LCH. Magnetic resonance imaging showed a solid mass extending from the sphenoid bone corpus to the left great wing of the sphenoid, left orbital apex, left posterior ethmoid cells, left cavernous sinus, and dural space. The correct decision for neuroimaging in patients with headaches is very important in terms of mortality and morbidity. We wanted to share our patient’s case who was diagnosed with LCH by presenting only with headache without any other systemic finding, to remind that LCH may be a secondary cause of headache.

Kaynakça

  • Kim S, Lee M, Shin HJ, Lee J, Suh YL. Coexistence of intracranial Langerhans cell histiocytosis and Erdheim-Chester disease in a pediatric patient: a case report. Childs Nerv Syst. 2016;32(5):893-6.
  • Grois N, Fahrner B, Arceci RJ, et al. Central nervous system disease in Langerhans cell histiocytosis. J Pediatr. 2010;156(6):873-881.e1.
  • Leung AKC, Lam JM, Leong KF. Childhood Langerhans cell histiocytosis: a disease with many faces. World J Pediatr. 2019;15(6):536-45.
  • Sagna Y, Courtillot C, Drabo JY, et al. Endocrine manifestations in a cohort of 63 adulthood and childhood onset patients with Langerhans cell histiocytosis. Eur J Endocrinol. 2019;181(3):275-85.
  • Nanduri VR, Lillywhite L, Chapman C, Parry L, Pritchard J, Vargha-Khadem F. Cognitive outcome of long-term survivors of multisystem langerhans cell histiocytosis: a single-institution, cross-sectional study. J Clin Oncol. 2003;21(15):2961-7.
  • Liang C, Liang Q, DU C, Zhang X, Guo S. Langerhans’ cell histiocytosis of the temporal fossa: A case report. Oncol Lett. 2016;11(4):2625-8.
  • Achour I, Kharrat I, Hbaieb Y, et al. Unusual Neurological Manifestation of Langerhans Cell Histiocytosis in an Adult. Ear Nose Throat J. 2022;1455613221106220.
  • Imashuku S, Ishida S, Koike K, et al. Cerebellar ataxia in pediatric patients with Langerhans cell histiocytosis. J Pediatr Hematol Oncol. 2004;26(11):735-9.
  • Algahtani H, Shirah B, Bajunaid M, Subahi A, Al-Maghraby H. Clinicoradiological Discrepancy in Multisystem Langerhans Cell Histiocytosis with Central Nervous System Involvement. Gulf J Oncolog. 2019;1(31):72-7.
  • Tommasino F, Cardamone C, Tortora V, Sabbatino F, Di Sarno C, Caputo A. Diagnosis of Langerhans cell histiocytosis on cytological examination of cerebrospinal fluid: Report of the first case. Diagn Cytopathol. 2022;50(12):E377-81.

Langerhans hücreli histiyositoz ile ilişkili bir çocukluk çağı sekonder baş ağrısı vakası

Yıl 2023, , 216 - 220, 23.05.2023
https://doi.org/10.21673/anadoluklin.1239361

Öz

Langerhans hücreli histiyositoz (LHH) tanılı hastalarda nörolojik tutulum oldukça nadirdir. Hastalığın seyri sırasında sistemik etkilere ek olarak baş ağrısı da görülebilir. 6 yaşında kız hasta herhangi bir sistemik semptomu olmaksızın sadece baş ağrısı şikayeti ile hastaneye başvurdu ve LHH tanısı aldı. Manyetik rezonans görüntülemede, sfenoid kemik korpusundan sfenoid kemiğin sol büyük kanadına, sol orbital apekse, sol posterior etmoid hücrelere, sol kavernöz sinüse ve dural boşluğa uzanan katı bir kitle olduğu tespit edildi. Baş ağrısı olan hastalarda nörogörüntüleme için doğru karar verilmesi mortalite ve morbidite açısından çok önemlidir. LHH’ nin sekonder bir baş ağrısı nedeni olabileceğinin göz ardı edilmemesi için başka bir sistemik bulgusu olmayan sadece baş ağrısı ile başvuran ve LHH tanısı konulan olgumuzu sunmaktayız.

Kaynakça

  • Kim S, Lee M, Shin HJ, Lee J, Suh YL. Coexistence of intracranial Langerhans cell histiocytosis and Erdheim-Chester disease in a pediatric patient: a case report. Childs Nerv Syst. 2016;32(5):893-6.
  • Grois N, Fahrner B, Arceci RJ, et al. Central nervous system disease in Langerhans cell histiocytosis. J Pediatr. 2010;156(6):873-881.e1.
  • Leung AKC, Lam JM, Leong KF. Childhood Langerhans cell histiocytosis: a disease with many faces. World J Pediatr. 2019;15(6):536-45.
  • Sagna Y, Courtillot C, Drabo JY, et al. Endocrine manifestations in a cohort of 63 adulthood and childhood onset patients with Langerhans cell histiocytosis. Eur J Endocrinol. 2019;181(3):275-85.
  • Nanduri VR, Lillywhite L, Chapman C, Parry L, Pritchard J, Vargha-Khadem F. Cognitive outcome of long-term survivors of multisystem langerhans cell histiocytosis: a single-institution, cross-sectional study. J Clin Oncol. 2003;21(15):2961-7.
  • Liang C, Liang Q, DU C, Zhang X, Guo S. Langerhans’ cell histiocytosis of the temporal fossa: A case report. Oncol Lett. 2016;11(4):2625-8.
  • Achour I, Kharrat I, Hbaieb Y, et al. Unusual Neurological Manifestation of Langerhans Cell Histiocytosis in an Adult. Ear Nose Throat J. 2022;1455613221106220.
  • Imashuku S, Ishida S, Koike K, et al. Cerebellar ataxia in pediatric patients with Langerhans cell histiocytosis. J Pediatr Hematol Oncol. 2004;26(11):735-9.
  • Algahtani H, Shirah B, Bajunaid M, Subahi A, Al-Maghraby H. Clinicoradiological Discrepancy in Multisystem Langerhans Cell Histiocytosis with Central Nervous System Involvement. Gulf J Oncolog. 2019;1(31):72-7.
  • Tommasino F, Cardamone C, Tortora V, Sabbatino F, Di Sarno C, Caputo A. Diagnosis of Langerhans cell histiocytosis on cytological examination of cerebrospinal fluid: Report of the first case. Diagn Cytopathol. 2022;50(12):E377-81.
Toplam 10 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm OLGU SUNUMU
Yazarlar

Yasemin Baranoğlu Kılınç 0000-0002-1795-5677

Ayşegül Danış 0000-0003-0962-2116

Sıddıka Halıcıoğlu 0000-0001-7091-5650

Yayımlanma Tarihi 23 Mayıs 2023
Kabul Tarihi 2 Mart 2023
Yayımlandığı Sayı Yıl 2023

Kaynak Göster

Vancouver Baranoğlu Kılınç Y, Danış A, Halıcıoğlu S. A childhood secondary headache case associated with Langerhans cell histiocytosis. Anadolu Klin. 2023;28(2):216-20.

13151 This Journal licensed under a CC BY-NC (Creative Commons Attribution-NonCommercial 4.0) International License.