Tip 2 Diyabette Koroner Arter Hastalığı Varlığı Serebrovasküler Hastalık İçin Bir Risk Faktörü müdür?

Yıl 2018, Cilt: 23 Sayı: 3, 173 - 176, 26.09.2018

Abdulhalim Şenyiğit

https://doi.org/10.21673/anadoluklin.403862

Öz

Amaç: Bu çalışmada, koroner arter hastalığı olan tip 2 diyabetik hastalar ile nefropatisi olan tip
2 diyabetik hastaları ana karotis intima–media kalınlığı açısından karşılaştırmak amaçlanmıştır.

Gereç ve Yöntemler: Çalışmaya koroner arter hastalığı olan tip 2 diyabetik hastalar (n=36) ve koroner
arter hastalığı olmayan, nefropati ile komplike tip 2 diyabetik hastalar (n=31) alındı. Sağ ve
sol ana karotis arter intima–media kalınlığı B-mod ultrasonografi ile değerlendirildi. Hastalarda
kardiyovasküler hastalık açısından diğer geleneksel risk faktörleri de değerlendirildi.

Bulgular: Koroner arter hastalığının eşlik ettiği diyabet hastalarında hem sağ hem de sol ana
karotis arter intima–media kalınlığı, sadece nefropatinin eşlik ettiği diyabet hastalarına göre anlamlı
derecede fazla bulundu (sağ ana karotis için 0,99 mm’ye 0,82 mm, sol ana karotis için 1,07
mm’ye 0,92 mm; her ikisi için de p<0,05). Hastalarda aterosklerotik diğer kardiyovasküler risk
faktörleri (LDL-kolesterol, HDL-kolesterol, sistolik ve diyastolik kan kan basıncı, diyabet yaşı) iki
grup arasında benzerdi (hepsi için p>0,05).

Tartışma ve Sonuç: Koroner arter hastalığı varlığı tip 2 diyabette eşlik eden serebrovasküler
hastalık için önemli bir göstergedir

Anahtar Kelimeler

Tip 2 diyabet, koroner arter hastalığı, karotis intima–media kalınlığı, serebrovasküler hastalık

Coronary Artery Disease in case of an already diagnosed Type 2 Diabetes, presents as an important risk factor for cerebrovascular disease.

Öz

Aim: This study aims to compare type 2 diabetic patients with coronary artery disease and type
2 diabetic patients with nephropathy in terms of common carotid artery intima–media thickness.

Materials and Methods: The study included type 2 diabetics with coronary artery disease
(n=36) and type 2 diabetics without coronary artery disease but with complicating nephropathy
(n=31). The right and left common carotid arteries were evaluated in terms of intima–media
thickness by using B-mode ultrasonography. Other traditional risk factors for cardiovascular
disease were also evaluated.

Results: Both right and left common carotid artery intima–media thicknesses were found to
be significantly greater for the diabetics with concomitant coronary artery disease than for the
diabetics with concomitant nephropathy only (0.99 mm vs 0.82 mm for the right and 1.07 mm
vs. 0.92 mm for the left common carotid artery; p<0.05 for both). Other atherosclerotic cardiovascular
risk factors (LDL-cholesterol, HDL-cholesterol, systolic and diastolic blood pressure,
diabetic age) were similar for both groups (p>0.05 for all).

Discussion and Conclusion: Presence of coronary artery disease is an important indicator for
concomitant cerebrovascular disease in type 2 diabetics

Anahtar Kelimeler

Type 2 diabetes, carotid artery intima-media thickness, coronary artery disease, cerebrovascular disease

Kaynakça

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