Effect of Reduced Meal Frequency During Ramadan Fasting on Retinal Vascular Caliper and Anterior Segment Parameters

Yıl 2020, Cilt: 25 Sayı: 1, 39 - 43, 15.01.2020

Mustafa Doğan , Mehmet Cem Sabaner , Mehmet Akif Erol

https://doi.org/10.21673/anadoluklin.578534

Öz

Aim: In
this study, we aimed to evaluate the effects of Ramadan fasting on retinal vascular
and anterior chamber parameters.

Materials and Methods: The study included 60 healthy eyes of 30 volunteers (15
males, 15 females) who visited our clinic between May and July 2017. We
performed measurements of intraocular pressure (IOP), anterior chamber volume (ACV),
central corneal thickness (CCT), central macular thickness (CMT), optic disc
retinal nerve fiber layer (OD-RNFL) and subfoveal choroidal thickness (SFCT) and
retinal vascular analysis (the central retinal artery equivalent [CRAE],
central retinal vein equivalent [CRVE], and artery-to-vein ratio [AVR]). The
measurements were repeated in the 4^th and 12^th hours of
the daily fasting period and 1^st postprandial hour on the last 5
days of the Ramadan month, and one month after the Ramadan month.

Results: The mean participant age was 29.30±8.12 years. The twelfth-hour SFCT, CRAE,
and CRVE measurements were statistically significantly lower than the values
measured one month after Ramadan (p=0.033, p=0.020, p=0.025, respectively). However,
no statistically significant difference was observed in the IOP, ACV, CCT, CMT,
OD-RNFL, and AVR measurements.

Discussion and Conclusion: We found that fasting for 12 hours or longer caused changes
in retinal vessel diameter and choroidal thickness.

Anahtar Kelimeler

choroidal thickness, spectral domain optical coherence tomography, Ramadan fasting, reduced meal frequency, retinal vascular parameters, spectral domain optical coherence tomography

Ramazan Orucunun Vasküler Retina ve Ön Kamara Parametrelerine Etkisi

Öz

 Amaç: Bu
çalışmada Ramazan orucunun vasküler retina ve ön kamara parametreleri üzerindeki
etkilerini değerlendirmek amaçlanmıştır

Gereç
ve Yöntemler: Mayıs—Temmuz 2017 döneminde kliniğimize gelen
30 gönüllünün (15 erkek, 15 kadın) 60 sağlıklı gözü çalışmaya alındı. Göz içi
basıncı (GİB), ön kamara hacmi (ÖKH), santral kornea kalınlığı (SSK), santral
makula kalınlığı (SMK), optik disk retina sinir lifi tabakası (OD-RSLT) ve
subfoveal koroit kalınlığı (SFKK) ölçümü ile retinal vasküler analiz (santral retinal arter damar değeri [SRAD],
santral retinal ven damar değeri [SRVD] ve arter/ven oranı [AVO])
gerçekleştirildi. Ölçümler Ramazan ayının son 5 gününde orucun 4. ve 12.
saatlerinde, iftardan 1 saat sonra ve Ramazan ayından 1 ay sonra tekrarlandı.

Bulgular: Katılımcı
yaş ortalaması 29,30±8,12 yıl idi. Orucun 12. saatindeki SFKK, SRAD ve SRVD
değerleri Ramazan ayından 1 ay sonra ölçülen değerlere kıyasla istatistiksel olarak
anlamlı şekilde daha düşüktü (sırasıyla p=0,033; p=0,020; p=0,025). Fakat GİB, ÖKH,
SSK, SMK, OD-RSLT ve AVO değerlerinde istatistiksel olarak anlamlı bir
değişiklik gözlenmedi.

Tartışma
ve Sonuç: On iki saat veya daha uzun süre oruç tutmanın retinal
damar değerlerinde ve koroit kalınlığında değişiklere yol açtığı saptanmıştır.

Anahtar Kelimeler

azaltılmış beslenme sıklığı, koroit kalınlığı, Ramazan orucu, retinal vasküler parametreler, spektral alan optik koherens tomografisi

Kaynakça

• 1. Brucculeri M, Hammel T, Harris A, et al. Regulation of intraocular pressure after water drinking. J Glaucoma 1999; 8:111-6.2. Dadeya S, Kamlesh, Shibal F, et al. Effect of religious fasting on intra-ocular pressure. Eye (Lond.) 2002;16:463–465.3. Kerimoglu H, Ozturk B, Gunduz K, et al. Effect of altered eating habits and periods during Ramadan fasting on intraocular pressure, tear secretion, corneal and anterior chamber parameters. Eye (Lond.) 2010;24:97–100.4.Selver ÖB, Palamar M, Gerceker K, et al.The Effects of Ramadan Fasting on Anterior Segment Parameters, Visual Acuity and Intraocular Pressures of the Eye. Open Ophthalmol J 2017;11:152–155.5.Larijani B, Zahedi F, Sanjari M, et al. The effect of Ramadan fasting on fasting serum glucose in healthy adults. Med J Malaysia 2003; 58:678-80.6.Azizi F. Research in Islamic fasting and health. Ann Saudi Med 2002;22:186-91.7.Al-Kaabi S, Bener A, Butt MT, et al. Effect of Ramadan fasting on peptic ulcer disease. Indian J Gastroenterol 2004;23:35.8.Al-Hadramy MS, Zawawi TH, Abdelwahab SM. Altered cortisol levels in relation to Ramadan.Eur J Clin Nutr 1988;42:359-62.9.Bogdan A, Bouchareb B, Touitou Y. Ramadan fasting alters endocrine and neuroendocrine circadian patterns. Meal-time as a synchronizer in humans? Life Sci 2001; 68:1607-15.10.Sarraf-Zadegan N, Atashi M, Naderi GA, et al. The effect of fasting in Ramadan on the values and interrelations between biochemical, coagulation and hematological factors. Ann Saudi Med 2000;20:377-81.11.Dadeya S, Kamlesh, Shibal F, et al. Effect of religious fasting on intra-ocular pressure. Eye (Lond) 2002;16:463-5.12.Knudtson MD, Lee KE, Hubbard LD, et al. Revised formulas for summarizing retinal vessel diameters. Curr Eye Res 2003;27:143–149.13.Burtis C.A., Ashwood E.R. Tietz. Textbook of Clinical Chemistry. 6th Edition. W.B. Saunders Company; 2007.14.Soleymani A, Rasoulinezhad S, Mahdipour E, et al. Effect of fasting on intraocular pressure (IOP) in normal individuals. J Babol Univ Med Sci 2009; 12:21.15.Kayikçioglu O, Güler C. Religious fasting and intraocular pressure. J. Glaucoma 2000;9:413–41416.Assadi M, Akrami A, Beikzadeh F, et al. Impact of Ramadan fasting on intraocular pressure, visual acuity and refractive errors. Singapore Med J 2011; 52:263-6.17.Vaajanen A, Luhtala S, Oksala O, et al. Does the renin-angiotensin system also regulate intra-ocular pressure? Ann Med 2008;40:418-27.