Bazı Karayosunu ve Ciğerotu Türlerinin Antimikrobiyal Aktivitesinin Belirlenmesi
Yıl 2021,
Cilt: 7 Sayı: 1, 1 - 7, 15.06.2021
Atakan Benek
,
Merve Şenturan
,
Özcan Şimşek
,
Kerem Canlı
,
Ergin Murat Altuner
Öz
Dünya üzerinde bulunan bitkilerin çoğunun hem yaraların iyileşme sürecini hızlandırmada hem de yaralanmaya bağlı enfeksiyonların tedavisinde etkili maddelere sahip oldukları bilinmektedir. Bilim insanları tarafından yapılan daha önceki çalışmalar, karayosunlarının ve ciğerotlarının da çeşitli bakteri ve mantarlara karşı antimikrobiyal ve antifungal aktiviteye sahip olduklarını göstermiştir. Bu çalışmada Philonotis seriata Mitt, Porella arboris-vitae (With.) Grolle, Porella platyphylla (L.) Pfeiff, Syntrichia calcicola J.J.Amann türlerinin etil alkol ekstraktlarının 8 gram pozitif, 9 gram negatif bakteri ve 1 maya olan toplam 18 suş üzerindeki antimikrobiyal aktivitelerinin analizi yapılmıştır. Yapılan analiz sonucunda tüm karayosunu ve ciğerotu örneklerinin birkaç suşa karşı antimikrobiyal aktiviteye sahip olduğu ve özellikle gram pozitif olan Staphylococcus aureus ve gram negatif olan Klebsiella pneumoniae üzerinde belirgin bir antimikrobiyal etki gösterdiği belirlenmiştir.
Kaynakça
- Altuner E.M. Çetin B. Çökmüş C. 2010. Tortella tortulosa (Hedw.) Limpr. Özütlerinin Antimikrobiyal Aktivitesi. Kastamonu University Journal of Forestry Faculty. 10:2, 111-116.
- Altuner E.M. Canlı K. Akata I. 2013. Antimicrobial Screening of Calliergonella cuspidata, Dicranum polysetum and Hypnum cupressiforme. Journal of Pure and Applied Microbiology. 1:8, 539-545.
- Altuner E.M. Canlı K. Akata I. 2014. In vitro Antimicrobial Screening of Hedwigia ciliata var. leucophaea and Determination of the Ethanol Extract Composition by Gas Chromatography/Mass Spectrometry (GC/MS). Journal of Pure and Applied Microbiology. 4:8, 2987-2998.
- Andrews J.M. 2003. BSAC standardized disc susceptibility testing method (version 6). Journal of Antimicrobial Chemotherapy, 60, 20-41.
- Asadollahi P. Farahani N.N. Mirzaii, M. Khoramrooz S.S. Van Belkum A. Asadollahi K. Darban-Sarokhalil D. 2018. Distribution of the most prevalent spa types among clinical isolates of methicillin-resistant and-susceptible Staphylococcus aureus around the world: a review. Frontiers in microbiology. 9, 163.
- Canlı K. Altuner E.M. Akata I. 2015. Antimicrobial screening of Mnium stellare. Bangladesh Journal of Pharmacology. 10, 321-325.
- Canlı K. Yetgin A. Akata I. Altuner E.M. 2016. In vitro Antimicrobial Screening of Aquilaria agallocha Roots. African Journal of Traditional, Complementary and Alternative medicines. 13:5, 178-181.
- Canlı K. Yetgin A. Benek A. Bozyel M. E. Altuner E.M. 2019. In Vitro Antimicrobial Activity Screening of Ethanol Extract of Lavandula stoechas and Investigation of Its Biochemical Composition. Advances in Pharmacological Sciences. Doi:10.1155/2019/3201458
- Core R Team. 2016. R: A language and environment for statistical computing. R Foundation for Statistical Computing. https://www.R-project.org/ [Erişim: 15 October 2020]
- Çolak E. Kara R. Ezer T. Çelik G.Y. Elibol B. 2011. Bazı Türk pleurokarpik yosunlarının antimikrobiyal aktivitesinin araştırılması. African Journal of Biotechnology. 10:60, 12905-12908.
- Duman R. Doğan H.H. Ali A.T.E.Ş. 2003. Morchella conica (Pers.) Boudier ve Suillus luteus (L.) SF Gray Makrofunguslarının Antimikrobiyal Aktiviteleri. Selçuk Üniversitesi Fen Fakültesi Fen Dergisi, 1:22, 19-24.
- Dülger B. Ceylan M. Alitsaous M. Uğurlu E. 1999. Artemisia absinthium L. (Pelin)’un antimikrobiyal aktivitesi. Turk. J. Biol. 23:3, 377-384.
- Dülger B. Hacioğlu N. Uyar G. 2009. Evaluation of antimicrobial activity of some mosses from Turkey. Asian J Chem. 21, 4093-4096.
- Lehman S. M. Mearns G. Rankin D. Cole R.A. Smrekar F. Branston S.D. Morales S. 2019. Design and preclinical development of a phage product for the treatment of antibiotic-resistant Staphylococcus aureus infections. Viruses. 11:1, 88.
- Oskay M. Aktaş K. Sarı D. Azeri C. 2007. Asphodelus aestivus (Liliaceae)’un antimikrobiyal etkisinin çukur ve disk difüzyon yöntemiyle karşılaştırmalı olarak belirlenmesi. Ekoloji. 62, 62-65.
- Savaroglu F. Ilhan S. Filik-Iscen C. 2011. An evaluation of the antimicrobial activity of some Turkish mosses. J Med Plants Res. 5, 3286-3292.
- Sevim E. Baş Y. Çelik G. Pınarbaşı M. Bozdeveci A. Özdemir T. Akpınar R. Yaylı N. Alpay Karaoğlu Ş. 2017. Antibacterial activity of bryophyte species against Paenibacillus larvae isolates Tukr J. Vet. Anım. Sci. 41, 521-531.
- Siu L.K. Yeh K.M. Lin J.C. Fung C.P. Chang F.Y. 2012. Klebsiella pneumoniae liver abscess: a new invasive syndrome. The Lancet infectious diseases. 12:11, 881-887.
- Uyar G. Doğru N. H. Ören M. Çavuş A. 2016. Determining Antibacterial Activity of Some Mosses (Cinclidotus riparius (Host ex Brid.) Arn., Calliergonella cuspidata (Hedw.) Loeske, Thamnobryum alopecurum (Hedw.) Gangulee, Leucobryum juniperoideum (Brid.) Müll. Hal., Cirriphyllum crassinervium (Taylor) Loeske & M. Fleisch.). Anatolian Bryology. 2:1-2, 1-8.
- Veljic M. Tarbuk M. Marin P.D. Ciric A. Sokovic M. Marin M. 2008. Antimicrobial Activity of Methanol Extracts of Mosses from Serbia. Pharmaceutical Biology. 46:12, 871-875.
- World Health Organization. 2014. Antimicrobial resistance: global report on surveillance. World Health Organization.
- Yetgin A. Şenturan M. Benek Efe E. Canlı K. 2017. Pterigynandrum filiforme Hedw. Türünün Antimikrobiyal Aktivitesinin Belirlenmesi. Anatolian Bryology. 3:1, 43-47.
- Zaidan M. R. Noor Rain A. Badrul A. R. Adlin A. Norazah A. Zakiah I. 2005. In vitro screening of five local medicinal plants for antibacterial activity using disc diffusion method. Trop biomed. 22:2, 165-170.
Determination of the Antimicrobial Activity of Some Moss and Liverwort Species
Yıl 2021,
Cilt: 7 Sayı: 1, 1 - 7, 15.06.2021
Atakan Benek
,
Merve Şenturan
,
Özcan Şimşek
,
Kerem Canlı
,
Ergin Murat Altuner
Öz
Most of the plants in the world are known to have effective substances both in accelerating the healing process of wounds and in the treatment of infections due to injury. Previous studies by scientists have shown that mosses and liverworts also have antimicrobial activity against various bacteria and fungi. In this study, the antimicrobial activities of ethyl alcohol extracts of Philonotis seriata Mitt, Porella arboris-vitae (With) Grolle, Porella platyphylla (L.) Pfeiff, Syntrichia calcicola J.J.Amann species were analyzed on a total of 18 strains, 8 gram positive, 9 gram negative bacteria and 1 yeast. As a result of the analysis, it was determined that all moss and liverwort samples have antimicrobial activity against a few strains and they have significant antimicrobial effects especially on gram-positive Staphylococcus aureus and gram-negative Klebsiella pneumoniae.
Kaynakça
- Altuner E.M. Çetin B. Çökmüş C. 2010. Tortella tortulosa (Hedw.) Limpr. Özütlerinin Antimikrobiyal Aktivitesi. Kastamonu University Journal of Forestry Faculty. 10:2, 111-116.
- Altuner E.M. Canlı K. Akata I. 2013. Antimicrobial Screening of Calliergonella cuspidata, Dicranum polysetum and Hypnum cupressiforme. Journal of Pure and Applied Microbiology. 1:8, 539-545.
- Altuner E.M. Canlı K. Akata I. 2014. In vitro Antimicrobial Screening of Hedwigia ciliata var. leucophaea and Determination of the Ethanol Extract Composition by Gas Chromatography/Mass Spectrometry (GC/MS). Journal of Pure and Applied Microbiology. 4:8, 2987-2998.
- Andrews J.M. 2003. BSAC standardized disc susceptibility testing method (version 6). Journal of Antimicrobial Chemotherapy, 60, 20-41.
- Asadollahi P. Farahani N.N. Mirzaii, M. Khoramrooz S.S. Van Belkum A. Asadollahi K. Darban-Sarokhalil D. 2018. Distribution of the most prevalent spa types among clinical isolates of methicillin-resistant and-susceptible Staphylococcus aureus around the world: a review. Frontiers in microbiology. 9, 163.
- Canlı K. Altuner E.M. Akata I. 2015. Antimicrobial screening of Mnium stellare. Bangladesh Journal of Pharmacology. 10, 321-325.
- Canlı K. Yetgin A. Akata I. Altuner E.M. 2016. In vitro Antimicrobial Screening of Aquilaria agallocha Roots. African Journal of Traditional, Complementary and Alternative medicines. 13:5, 178-181.
- Canlı K. Yetgin A. Benek A. Bozyel M. E. Altuner E.M. 2019. In Vitro Antimicrobial Activity Screening of Ethanol Extract of Lavandula stoechas and Investigation of Its Biochemical Composition. Advances in Pharmacological Sciences. Doi:10.1155/2019/3201458
- Core R Team. 2016. R: A language and environment for statistical computing. R Foundation for Statistical Computing. https://www.R-project.org/ [Erişim: 15 October 2020]
- Çolak E. Kara R. Ezer T. Çelik G.Y. Elibol B. 2011. Bazı Türk pleurokarpik yosunlarının antimikrobiyal aktivitesinin araştırılması. African Journal of Biotechnology. 10:60, 12905-12908.
- Duman R. Doğan H.H. Ali A.T.E.Ş. 2003. Morchella conica (Pers.) Boudier ve Suillus luteus (L.) SF Gray Makrofunguslarının Antimikrobiyal Aktiviteleri. Selçuk Üniversitesi Fen Fakültesi Fen Dergisi, 1:22, 19-24.
- Dülger B. Ceylan M. Alitsaous M. Uğurlu E. 1999. Artemisia absinthium L. (Pelin)’un antimikrobiyal aktivitesi. Turk. J. Biol. 23:3, 377-384.
- Dülger B. Hacioğlu N. Uyar G. 2009. Evaluation of antimicrobial activity of some mosses from Turkey. Asian J Chem. 21, 4093-4096.
- Lehman S. M. Mearns G. Rankin D. Cole R.A. Smrekar F. Branston S.D. Morales S. 2019. Design and preclinical development of a phage product for the treatment of antibiotic-resistant Staphylococcus aureus infections. Viruses. 11:1, 88.
- Oskay M. Aktaş K. Sarı D. Azeri C. 2007. Asphodelus aestivus (Liliaceae)’un antimikrobiyal etkisinin çukur ve disk difüzyon yöntemiyle karşılaştırmalı olarak belirlenmesi. Ekoloji. 62, 62-65.
- Savaroglu F. Ilhan S. Filik-Iscen C. 2011. An evaluation of the antimicrobial activity of some Turkish mosses. J Med Plants Res. 5, 3286-3292.
- Sevim E. Baş Y. Çelik G. Pınarbaşı M. Bozdeveci A. Özdemir T. Akpınar R. Yaylı N. Alpay Karaoğlu Ş. 2017. Antibacterial activity of bryophyte species against Paenibacillus larvae isolates Tukr J. Vet. Anım. Sci. 41, 521-531.
- Siu L.K. Yeh K.M. Lin J.C. Fung C.P. Chang F.Y. 2012. Klebsiella pneumoniae liver abscess: a new invasive syndrome. The Lancet infectious diseases. 12:11, 881-887.
- Uyar G. Doğru N. H. Ören M. Çavuş A. 2016. Determining Antibacterial Activity of Some Mosses (Cinclidotus riparius (Host ex Brid.) Arn., Calliergonella cuspidata (Hedw.) Loeske, Thamnobryum alopecurum (Hedw.) Gangulee, Leucobryum juniperoideum (Brid.) Müll. Hal., Cirriphyllum crassinervium (Taylor) Loeske & M. Fleisch.). Anatolian Bryology. 2:1-2, 1-8.
- Veljic M. Tarbuk M. Marin P.D. Ciric A. Sokovic M. Marin M. 2008. Antimicrobial Activity of Methanol Extracts of Mosses from Serbia. Pharmaceutical Biology. 46:12, 871-875.
- World Health Organization. 2014. Antimicrobial resistance: global report on surveillance. World Health Organization.
- Yetgin A. Şenturan M. Benek Efe E. Canlı K. 2017. Pterigynandrum filiforme Hedw. Türünün Antimikrobiyal Aktivitesinin Belirlenmesi. Anatolian Bryology. 3:1, 43-47.
- Zaidan M. R. Noor Rain A. Badrul A. R. Adlin A. Norazah A. Zakiah I. 2005. In vitro screening of five local medicinal plants for antibacterial activity using disc diffusion method. Trop biomed. 22:2, 165-170.