The effect of tolmetin on tendon healing (A biomechanical study on rabbits)

Cilt: 33 Sayı: 3 11 Eylül 2006
  • Gokhan Maralcan
  • Erol Gokturk
  • Akin Turgut
  • Nusret Kose
  • Sinan Seber
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The effect of tolmetin on tendon healing (A biomechanical study on rabbits)

Öz

Introduction: The use of NSAIDs are common after musculoskeletal injury or surgeries. The influence of NSAID on tendon healing is controversial. We evaluated the effect of tolmetin on tendon healing. Material and Method: 12 Male New Zealand rabbits randomly selected and tenotomy of the right achilles tendon and cast immobilization in flexion was performed. While 6 rabbits in experimental group receiving 25 mg/kg/day tolmetin via intraperitoneal injection other 6 rabbits consisted the control group and not given tolmetin. All the rabbits were sacrified and achilles tendons were resected at 14 th day. On material testing machine biomechanical evaluation was made. Average tensile force-to-failure was 33.81 newton (N) for the experimental group and 36.95 N for the control group. No statistically significant difference between the groups was found. Discussion: Because the first stage of tendon healing is inflammation, one may expect that while NSAIDs reducing pain and swelling thus providing clinical benefits on the other hand they may interfere with tendon healing. We found that tolmetin has no adverse effect on healing of conservatively treated achilles tendon rupture. Conclusion: During tendon healing tolmetin and probably other similar NSAIDs may be useful since these drugs can reduce adhesions caused by surgery to minimum and increase gliding function of tendon thus an optimum clinical result can be obtained.

Anahtar Kelimeler

Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

-

Yazarlar

Gokhan Maralcan Bu kişi benim

Erol Gokturk Bu kişi benim

Akin Turgut Bu kişi benim

Nusret Kose Bu kişi benim

Sinan Seber Bu kişi benim

Yayımlanma Tarihi

11 Eylül 2006

Gönderilme Tarihi

6 Mart 2014

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 1999 Cilt: 33 Sayı: 3

Kaynak Göster

APA
Maralcan, G., Gokturk, E., Turgut, A., Kose, N., & Seber, S. (2006). The effect of tolmetin on tendon healing (A biomechanical study on rabbits). Acta Orthopaedica et Traumatologica Turcica, 33(3), 216-220. https://doi.org/10.3944/aott.v33i3.2340
AMA
1.Maralcan G, Gokturk E, Turgut A, Kose N, Seber S. The effect of tolmetin on tendon healing (A biomechanical study on rabbits). Acta Orthopaedica et Traumatologica Turcica. 2006;33(3):216-220. doi:10.3944/aott.v33i3.2340
Chicago
Maralcan, Gokhan, Erol Gokturk, Akin Turgut, Nusret Kose, ve Sinan Seber. 2006. “The effect of tolmetin on tendon healing (A biomechanical study on rabbits)”. Acta Orthopaedica et Traumatologica Turcica 33 (3): 216-20. https://doi.org/10.3944/aott.v33i3.2340.
EndNote
Maralcan G, Gokturk E, Turgut A, Kose N, Seber S (01 Eylül 2006) The effect of tolmetin on tendon healing (A biomechanical study on rabbits). Acta Orthopaedica et Traumatologica Turcica 33 3 216–220.
IEEE
[1]G. Maralcan, E. Gokturk, A. Turgut, N. Kose, ve S. Seber, “The effect of tolmetin on tendon healing (A biomechanical study on rabbits)”, Acta Orthopaedica et Traumatologica Turcica, c. 33, sy 3, ss. 216–220, Eyl. 2006, doi: 10.3944/aott.v33i3.2340.
ISNAD
Maralcan, Gokhan - Gokturk, Erol - Turgut, Akin - Kose, Nusret - Seber, Sinan. “The effect of tolmetin on tendon healing (A biomechanical study on rabbits)”. Acta Orthopaedica et Traumatologica Turcica 33/3 (01 Eylül 2006): 216-220. https://doi.org/10.3944/aott.v33i3.2340.
JAMA
1.Maralcan G, Gokturk E, Turgut A, Kose N, Seber S. The effect of tolmetin on tendon healing (A biomechanical study on rabbits). Acta Orthopaedica et Traumatologica Turcica. 2006;33:216–220.
MLA
Maralcan, Gokhan, vd. “The effect of tolmetin on tendon healing (A biomechanical study on rabbits)”. Acta Orthopaedica et Traumatologica Turcica, c. 33, sy 3, Eylül 2006, ss. 216-20, doi:10.3944/aott.v33i3.2340.
Vancouver
1.Gokhan Maralcan, Erol Gokturk, Akin Turgut, Nusret Kose, Sinan Seber. The effect of tolmetin on tendon healing (A biomechanical study on rabbits). Acta Orthopaedica et Traumatologica Turcica. 01 Eylül 2006;33(3):216-20. doi:10.3944/aott.v33i3.2340